Timeliness of routine childhood vaccinations in Indonesian infants in the first year of life
Background: Vaccines have proven to be one of the most effective strategies to control infectious diseases and contributed to childhood survival. While high vaccine coverages provide individual's and herd immunity, age-appropriate vaccination or vaccine timeliness is important for maximum vacci...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier Ltd
2022
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| Online Access: | https://repository.ugm.ac.id/283219/1/30.pdf |
| _version_ | 1826050606346797056 |
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| author | Oktaria, Vicka Bines, Julie E Murni, Indah K Dinari, Rizka Indraswari, Bragmandita W Alvianita, Audesia Putri, Dwi AD Danchin, Margaret |
| author_facet | Oktaria, Vicka Bines, Julie E Murni, Indah K Dinari, Rizka Indraswari, Bragmandita W Alvianita, Audesia Putri, Dwi AD Danchin, Margaret |
| author_sort | Oktaria, Vicka |
| collection | UGM |
| description | Background: Vaccines have proven to be one of the most effective strategies to control infectious diseases and contributed to childhood survival. While high vaccine coverages provide individual's and herd immunity, age-appropriate vaccination or vaccine timeliness is important for maximum vaccine's protection, but often not evaluated. We aimed to describe the timeliness of childhood vaccination for Indonesian infants and identify risk factors associated with delayed vaccination. Methods: This study was a sub-study of the Indonesian Pneumonia and Vitamin D status (IPAD) study, a community-based cohort study to investigate pneumonia incidence in two districts in Yogyakarta province, Indonesia. Socio-demographic data were obtained from structured interviews and vaccine status was obtained from maternal and child health records. Timely vaccination was defined if the vaccine was received between four days or less before and within 28 days after the recommended age of vaccination. Results: 359 (85) out of 422 IPAD participants and their immunisation records were included. Between December 2015 and December 2017, vaccination coverage was high and ranged from 96.1 (Measles) to 100 (DTP-HepB-Hib 1). However, two thirds (67, 242/359) of all participants had received either early or late vaccines, with dose 2 IPV (40, 143/356), dose 3 IPV (56, 196/349) and dose 3 DTP-HepB-Hib (29, 103/354) most delayed, and only 1 received early doses. The main risk factors for untimely vaccination were if the infant was born in a private practice versus in a public health facility (AOR 1.90; 95 CI: 1.18–3.07) and rural residence (AOR 1.84; 95 CI: 1.15–2.94). Conclusions: Despite high vaccine coverage for Indonesian infants (>95), two thirds (67) of infants had untimely vaccinations, with dose 3 IPV (56) the most delayed. Future strategies should focus on coordination between government, health care providers, and carers to ensure timely access and vaccination of infants to ensure adherence to vaccination schedules. © 2022 Elsevier Ltd |
| first_indexed | 2024-03-14T00:07:03Z |
| format | Article |
| id | oai:generic.eprints.org:283219 |
| institution | Universiti Gadjah Mada |
| language | English |
| last_indexed | 2024-03-14T00:07:03Z |
| publishDate | 2022 |
| publisher | Elsevier Ltd |
| record_format | dspace |
| spelling | oai:generic.eprints.org:2832192023-11-21T01:10:38Z https://repository.ugm.ac.id/283219/ Timeliness of routine childhood vaccinations in Indonesian infants in the first year of life Oktaria, Vicka Bines, Julie E Murni, Indah K Dinari, Rizka Indraswari, Bragmandita W Alvianita, Audesia Putri, Dwi AD Danchin, Margaret Immunology not elsewhere classified Background: Vaccines have proven to be one of the most effective strategies to control infectious diseases and contributed to childhood survival. While high vaccine coverages provide individual's and herd immunity, age-appropriate vaccination or vaccine timeliness is important for maximum vaccine's protection, but often not evaluated. We aimed to describe the timeliness of childhood vaccination for Indonesian infants and identify risk factors associated with delayed vaccination. Methods: This study was a sub-study of the Indonesian Pneumonia and Vitamin D status (IPAD) study, a community-based cohort study to investigate pneumonia incidence in two districts in Yogyakarta province, Indonesia. Socio-demographic data were obtained from structured interviews and vaccine status was obtained from maternal and child health records. Timely vaccination was defined if the vaccine was received between four days or less before and within 28 days after the recommended age of vaccination. Results: 359 (85) out of 422 IPAD participants and their immunisation records were included. Between December 2015 and December 2017, vaccination coverage was high and ranged from 96.1 (Measles) to 100 (DTP-HepB-Hib 1). However, two thirds (67, 242/359) of all participants had received either early or late vaccines, with dose 2 IPV (40, 143/356), dose 3 IPV (56, 196/349) and dose 3 DTP-HepB-Hib (29, 103/354) most delayed, and only 1 received early doses. The main risk factors for untimely vaccination were if the infant was born in a private practice versus in a public health facility (AOR 1.90; 95 CI: 1.18–3.07) and rural residence (AOR 1.84; 95 CI: 1.15–2.94). Conclusions: Despite high vaccine coverage for Indonesian infants (>95), two thirds (67) of infants had untimely vaccinations, with dose 3 IPV (56) the most delayed. Future strategies should focus on coordination between government, health care providers, and carers to ensure timely access and vaccination of infants to ensure adherence to vaccination schedules. © 2022 Elsevier Ltd Elsevier Ltd 2022 Article PeerReviewed application/pdf en https://repository.ugm.ac.id/283219/1/30.pdf Oktaria, Vicka and Bines, Julie E and Murni, Indah K and Dinari, Rizka and Indraswari, Bragmandita W and Alvianita, Audesia and Putri, Dwi AD and Danchin, Margaret (2022) Timeliness of routine childhood vaccinations in Indonesian infants in the first year of life. Vaccine, 40 (21). 2925 -2932. ISSN 1873-2518 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85129400077&doi=10.1016%2fj.vaccine.2022.04.001&partnerID=40&md5=61513f7940743da6d4777f06adebb82a 10.1016/j.vaccine.2022.04.001 |
| spellingShingle | Immunology not elsewhere classified Oktaria, Vicka Bines, Julie E Murni, Indah K Dinari, Rizka Indraswari, Bragmandita W Alvianita, Audesia Putri, Dwi AD Danchin, Margaret Timeliness of routine childhood vaccinations in Indonesian infants in the first year of life |
| title | Timeliness of routine childhood vaccinations in Indonesian infants in the first year of life |
| title_full | Timeliness of routine childhood vaccinations in Indonesian infants in the first year of life |
| title_fullStr | Timeliness of routine childhood vaccinations in Indonesian infants in the first year of life |
| title_full_unstemmed | Timeliness of routine childhood vaccinations in Indonesian infants in the first year of life |
| title_short | Timeliness of routine childhood vaccinations in Indonesian infants in the first year of life |
| title_sort | timeliness of routine childhood vaccinations in indonesian infants in the first year of life |
| topic | Immunology not elsewhere classified |
| url | https://repository.ugm.ac.id/283219/1/30.pdf |
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