Symptom clusters change over time among patients with gynecological cancer receiving chemotherapy
Purpose: This study aimed to explore symptom clusters at different time points among patients with gynecological cancer undergoing chemotherapy. Methods: A longitudinal design was used to explore the patterns of symptom clusters four times: during prechemotherapy (T0), first (T1), second (T2), an...
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| Format: | Article |
| Language: | English |
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Elsevier
2022
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| Online Access: | https://repository.ugm.ac.id/283918/1/1-s2.0-S1462388922001016-main.pdf |
| _version_ | 1797037762948366336 |
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| author | Haryani, Haryani Hsu, Yu-Yun Wang, Shan-Tair |
| author_facet | Haryani, Haryani Hsu, Yu-Yun Wang, Shan-Tair |
| author_sort | Haryani, Haryani |
| collection | UGM |
| description | Purpose: This study aimed to explore symptom clusters at different time points among patients with gynecological cancer undergoing chemotherapy.
Methods: A longitudinal design was used to explore the patterns of symptom clusters four times: during prechemotherapy (T0), first (T1), second (T2), and third (T3) cycles of chemotherapy. The Memorial Symptom Assessment Scale was used to assess the dimension of symptoms. The study was conducted in Indonesia. Exploratory factor analysis was used to analyze the structures of symptom clusters across time.
Results: A total of 120 subjects provided baseline data, and 82 were retained at T3. Before chemotherapy, the most prevalent symptoms were pain and difficulty in sleeping. However, after starting chemotherapy, the patients suffered from chemotherapy-related side effects, including nausea, change in taste, lack of appetite, hair loss, fatigue, and feeling of “I don't look like myself.” Six symptom clusters were identified in patients with gynecological cancer across four time points during chemotherapy: pain-related, nutritional, emotional, hormonal-related, fatigue-related, and body-image symptom clusters. Nutrition and emotion symptom clusters occurred consistently from T0 to T3, fatigue-related clusters appeared after chemotherapy at T1 and T2, and body-image symptom clusters emerged at late T2 and T3.
Conclusion: The structures of symptom clusters in this study were dynamic and various. The nutrition and emotional-related symptoms constituted a cluster during chemotherapy. Oncology nurses should provide physical and psychosocial interventions to relieve these symptoms in patients with gynecological cancer undergoing chemotherapy. |
| first_indexed | 2024-03-14T00:08:55Z |
| format | Article |
| id | oai:generic.eprints.org:283918 |
| institution | Universiti Gadjah Mada |
| language | English |
| last_indexed | 2024-03-14T00:08:55Z |
| publishDate | 2022 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | oai:generic.eprints.org:2839182023-11-24T02:47:58Z https://repository.ugm.ac.id/283918/ Symptom clusters change over time among patients with gynecological cancer receiving chemotherapy Haryani, Haryani Hsu, Yu-Yun Wang, Shan-Tair Oncology and Carcinogenesis Chemotherapy Purpose: This study aimed to explore symptom clusters at different time points among patients with gynecological cancer undergoing chemotherapy. Methods: A longitudinal design was used to explore the patterns of symptom clusters four times: during prechemotherapy (T0), first (T1), second (T2), and third (T3) cycles of chemotherapy. The Memorial Symptom Assessment Scale was used to assess the dimension of symptoms. The study was conducted in Indonesia. Exploratory factor analysis was used to analyze the structures of symptom clusters across time. Results: A total of 120 subjects provided baseline data, and 82 were retained at T3. Before chemotherapy, the most prevalent symptoms were pain and difficulty in sleeping. However, after starting chemotherapy, the patients suffered from chemotherapy-related side effects, including nausea, change in taste, lack of appetite, hair loss, fatigue, and feeling of “I don't look like myself.” Six symptom clusters were identified in patients with gynecological cancer across four time points during chemotherapy: pain-related, nutritional, emotional, hormonal-related, fatigue-related, and body-image symptom clusters. Nutrition and emotion symptom clusters occurred consistently from T0 to T3, fatigue-related clusters appeared after chemotherapy at T1 and T2, and body-image symptom clusters emerged at late T2 and T3. Conclusion: The structures of symptom clusters in this study were dynamic and various. The nutrition and emotional-related symptoms constituted a cluster during chemotherapy. Oncology nurses should provide physical and psychosocial interventions to relieve these symptoms in patients with gynecological cancer undergoing chemotherapy. Elsevier 2022-08-18 Article PeerReviewed application/pdf en https://repository.ugm.ac.id/283918/1/1-s2.0-S1462388922001016-main.pdf Haryani, Haryani and Hsu, Yu-Yun and Wang, Shan-Tair (2022) Symptom clusters change over time among patients with gynecological cancer receiving chemotherapy. European Journal of Oncology Nursing, 60. ISSN 14623889 https://www.sciencedirect.com/science/article/pii/S1462388922001016 10.1016/j.ejon.2022.102193 |
| spellingShingle | Oncology and Carcinogenesis Chemotherapy Haryani, Haryani Hsu, Yu-Yun Wang, Shan-Tair Symptom clusters change over time among patients with gynecological cancer receiving chemotherapy |
| title | Symptom clusters change over time among patients with gynecological cancer receiving chemotherapy |
| title_full | Symptom clusters change over time among patients with gynecological cancer receiving chemotherapy |
| title_fullStr | Symptom clusters change over time among patients with gynecological cancer receiving chemotherapy |
| title_full_unstemmed | Symptom clusters change over time among patients with gynecological cancer receiving chemotherapy |
| title_short | Symptom clusters change over time among patients with gynecological cancer receiving chemotherapy |
| title_sort | symptom clusters change over time among patients with gynecological cancer receiving chemotherapy |
| topic | Oncology and Carcinogenesis Chemotherapy |
| url | https://repository.ugm.ac.id/283918/1/1-s2.0-S1462388922001016-main.pdf |
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