Relation between f3-carotene and ferritinupon malondialdehyde in Javanese male smoker

Smoking of cigarette can cause additional free radicals. Oxidative damage is resulted from the accumulation of free radicals in the body. Malondialdehyde (MDA) is the end product of free radicals, a marker of oxidative damage. B-carotene is pro-vitamin A, an antioxidant known to quench singlet oxyge...

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Bibliographic Details
Main Author: Perpustakaan UGM, i-lib
Format: Article
Published: [Yogyakarta] : Universitas Gadjah Mada 2011
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Summary:Smoking of cigarette can cause additional free radicals. Oxidative damage is resulted from the accumulation of free radicals in the body. Malondialdehyde (MDA) is the end product of free radicals, a marker of oxidative damage. B-carotene is pro-vitamin A, an antioxidant known to quench singlet oxygen. Ferritin is thought to release excessive iron in smokers, thereby increasing the oxidative stress. The aim of the study is to evaluate the relation between b-carotene and ferritin toward MDA level in Javanese smokers. This study was carried out in a case-control, cross sectional design nested with cluster sampling. Participants were Javanese smokers and non-smokers in Purworejo district, Central Java. Samples and data were obtained secondarily. The results were analyzed using independent samples t-test and linear regression. The results showed that there was very weak negative corelation between B-carotene with MDA (Rsquare= 0.013