Screening and Toxicity Assay of Bioactive Compounds from Ethyl Acetate Extract of Indonesian Marine Sponge Dysidia sp. from Hoga Island
Screening of the toxic active compounds from the ethyl acetate fraction of the sponge Dysidea sp. from Hoga Island, Wakatobi National Park has been conducted. Isolation was carried out by extraction method using methanol as solvent. Then the extract was partitioned using various solvents, such as n-...
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| Format: | Other |
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Materials Science Forum
2022
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| author | Ramadhan, Muhammad Fajri Astuti, Endang Swasono, Respati Tri |
| author_facet | Ramadhan, Muhammad Fajri Astuti, Endang Swasono, Respati Tri |
| author_sort | Ramadhan, Muhammad Fajri |
| collection | UGM |
| description | Screening of the toxic active compounds from the ethyl acetate fraction of the sponge Dysidea sp. from Hoga Island, Wakatobi National Park has been conducted. Isolation was carried out by extraction method using methanol as solvent. Then the extract was partitioned using various solvents, such as n-Hexane, dichloromethane, ethyl acetate, and acetone. The obtained fractions were then tested for toxicity using the Brine Shrimp Lethality Test (BSLT) and phytochemical test. The compounds with toxic properties were then identified using Liquid Chromatography-High Resolution Mass Spectrometry (LC-HRMS). The ethyl acetate fraction obtained was 1.5 g in a solid green paste. LC-HRMS analysis showed that the ethyl acetate fraction contained 3 reported compounds and 2 unreported compounds |
| first_indexed | 2024-03-14T00:10:29Z |
| format | Other |
| id | oai:generic.eprints.org:284481 |
| institution | Universiti Gadjah Mada |
| last_indexed | 2024-03-14T00:10:29Z |
| publishDate | 2022 |
| publisher | Materials Science Forum |
| record_format | dspace |
| spelling | oai:generic.eprints.org:2844812024-01-04T03:07:36Z https://repository.ugm.ac.id/284481/ Screening and Toxicity Assay of Bioactive Compounds from Ethyl Acetate Extract of Indonesian Marine Sponge Dysidia sp. from Hoga Island Ramadhan, Muhammad Fajri Astuti, Endang Swasono, Respati Tri Chemical Science Screening of the toxic active compounds from the ethyl acetate fraction of the sponge Dysidea sp. from Hoga Island, Wakatobi National Park has been conducted. Isolation was carried out by extraction method using methanol as solvent. Then the extract was partitioned using various solvents, such as n-Hexane, dichloromethane, ethyl acetate, and acetone. The obtained fractions were then tested for toxicity using the Brine Shrimp Lethality Test (BSLT) and phytochemical test. The compounds with toxic properties were then identified using Liquid Chromatography-High Resolution Mass Spectrometry (LC-HRMS). The ethyl acetate fraction obtained was 1.5 g in a solid green paste. LC-HRMS analysis showed that the ethyl acetate fraction contained 3 reported compounds and 2 unreported compounds Materials Science Forum 2022 Other NonPeerReviewed Ramadhan, Muhammad Fajri and Astuti, Endang and Swasono, Respati Tri (2022) Screening and Toxicity Assay of Bioactive Compounds from Ethyl Acetate Extract of Indonesian Marine Sponge Dysidia sp. from Hoga Island. Materials Science Forum. https://www.scientific.net/MSF.1061.165 10.4028/p-rg4242 |
| spellingShingle | Chemical Science Ramadhan, Muhammad Fajri Astuti, Endang Swasono, Respati Tri Screening and Toxicity Assay of Bioactive Compounds from Ethyl Acetate Extract of Indonesian Marine Sponge Dysidia sp. from Hoga Island |
| title | Screening and Toxicity Assay of Bioactive Compounds from Ethyl Acetate Extract of Indonesian Marine Sponge Dysidia sp. from Hoga Island |
| title_full | Screening and Toxicity Assay of Bioactive Compounds from Ethyl Acetate Extract of Indonesian Marine Sponge Dysidia sp. from Hoga Island |
| title_fullStr | Screening and Toxicity Assay of Bioactive Compounds from Ethyl Acetate Extract of Indonesian Marine Sponge Dysidia sp. from Hoga Island |
| title_full_unstemmed | Screening and Toxicity Assay of Bioactive Compounds from Ethyl Acetate Extract of Indonesian Marine Sponge Dysidia sp. from Hoga Island |
| title_short | Screening and Toxicity Assay of Bioactive Compounds from Ethyl Acetate Extract of Indonesian Marine Sponge Dysidia sp. from Hoga Island |
| title_sort | screening and toxicity assay of bioactive compounds from ethyl acetate extract of indonesian marine sponge dysidia sp from hoga island |
| topic | Chemical Science |
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