SYDNONE DERIVATIVES A SYNTHONS FOR NOVEL MESOIONIC COMPOUNDS. SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL EVALUATION OF SOME 2-(4'-SUBSTITUTED ANILINOSYNDON-3'-Yl)-1, 3, 4-THIADIAZINO (6, 5-B) INDOLES
In the present study, a series of 2-(4'-Substitutedanilinosydnon-3'-yl)-1, 3, 4-thiadiazino (6, 5-b) indoles 7a-j have been synthesized. All the synthesized compounds have been characterized by elemental and spectral (I R, 1H-NMR and Mass) spectrometric analysis. Furthermore, above mention...
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[Yogyakarta] : Universitas Gadjah Mada
2011
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| _version_ | 1826033383295156224 |
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| author | Perpustakaan UGM, i-lib |
| author_facet | Perpustakaan UGM, i-lib |
| author_sort | Perpustakaan UGM, i-lib |
| collection | UGM |
| description | In the present study, a series of 2-(4'-Substitutedanilinosydnon-3'-yl)-1, 3, 4-thiadiazino (6, 5-b) indoles 7a-j have been synthesized. All the synthesized compounds have been characterized by elemental and spectral (I R, 1H-NMR and Mass) spectrometric analysis. Furthermore, above mentioned compounds were evaluated for their antibacterial and antifungal activities against selected panel of pathogenic strains. Ampicillin trihydrate, ofloxacin and fluconazole, griseofulvin were used as standard drugs for antibacterial and anifungal activity respectively. Compound was found the most potent one with lesser toxicity in the prepared indole derivatives. |
| first_indexed | 2024-03-05T23:13:47Z |
| format | Article |
| id | oai:generic.eprints.org:29245 |
| institution | Universiti Gadjah Mada |
| last_indexed | 2024-03-05T23:13:47Z |
| publishDate | 2011 |
| publisher | [Yogyakarta] : Universitas Gadjah Mada |
| record_format | dspace |
| spelling | oai:generic.eprints.org:292452014-06-18T00:23:45Z https://repository.ugm.ac.id/29245/ SYDNONE DERIVATIVES A SYNTHONS FOR NOVEL MESOIONIC COMPOUNDS. SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL EVALUATION OF SOME 2-(4'-SUBSTITUTED ANILINOSYNDON-3'-Yl)-1, 3, 4-THIADIAZINO (6, 5-B) INDOLES Perpustakaan UGM, i-lib Jurnal i-lib UGM In the present study, a series of 2-(4'-Substitutedanilinosydnon-3'-yl)-1, 3, 4-thiadiazino (6, 5-b) indoles 7a-j have been synthesized. All the synthesized compounds have been characterized by elemental and spectral (I R, 1H-NMR and Mass) spectrometric analysis. Furthermore, above mentioned compounds were evaluated for their antibacterial and antifungal activities against selected panel of pathogenic strains. Ampicillin trihydrate, ofloxacin and fluconazole, griseofulvin were used as standard drugs for antibacterial and anifungal activity respectively. Compound was found the most potent one with lesser toxicity in the prepared indole derivatives. [Yogyakarta] : Universitas Gadjah Mada 2011 Article NonPeerReviewed Perpustakaan UGM, i-lib (2011) SYDNONE DERIVATIVES A SYNTHONS FOR NOVEL MESOIONIC COMPOUNDS. SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL EVALUATION OF SOME 2-(4'-SUBSTITUTED ANILINOSYNDON-3'-Yl)-1, 3, 4-THIADIAZINO (6, 5-B) INDOLES. Jurnal i-lib UGM. http://i-lib.ugm.ac.id/jurnal/download.php?dataId=12308 |
| spellingShingle | Jurnal i-lib UGM Perpustakaan UGM, i-lib SYDNONE DERIVATIVES A SYNTHONS FOR NOVEL MESOIONIC COMPOUNDS. SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL EVALUATION OF SOME 2-(4'-SUBSTITUTED ANILINOSYNDON-3'-Yl)-1, 3, 4-THIADIAZINO (6, 5-B) INDOLES |
| title | SYDNONE DERIVATIVES A SYNTHONS FOR NOVEL MESOIONIC COMPOUNDS. SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL EVALUATION OF SOME 2-(4'-SUBSTITUTED ANILINOSYNDON-3'-Yl)-1, 3, 4-THIADIAZINO (6, 5-B) INDOLES |
| title_full | SYDNONE DERIVATIVES A SYNTHONS FOR NOVEL MESOIONIC COMPOUNDS. SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL EVALUATION OF SOME 2-(4'-SUBSTITUTED ANILINOSYNDON-3'-Yl)-1, 3, 4-THIADIAZINO (6, 5-B) INDOLES |
| title_fullStr | SYDNONE DERIVATIVES A SYNTHONS FOR NOVEL MESOIONIC COMPOUNDS. SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL EVALUATION OF SOME 2-(4'-SUBSTITUTED ANILINOSYNDON-3'-Yl)-1, 3, 4-THIADIAZINO (6, 5-B) INDOLES |
| title_full_unstemmed | SYDNONE DERIVATIVES A SYNTHONS FOR NOVEL MESOIONIC COMPOUNDS. SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL EVALUATION OF SOME 2-(4'-SUBSTITUTED ANILINOSYNDON-3'-Yl)-1, 3, 4-THIADIAZINO (6, 5-B) INDOLES |
| title_short | SYDNONE DERIVATIVES A SYNTHONS FOR NOVEL MESOIONIC COMPOUNDS. SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL EVALUATION OF SOME 2-(4'-SUBSTITUTED ANILINOSYNDON-3'-Yl)-1, 3, 4-THIADIAZINO (6, 5-B) INDOLES |
| title_sort | sydnone derivatives a synthons for novel mesoionic compounds synthesis characterization and antimicrobial evaluation of some 2 4 substituted anilinosyndon 3 yl 1 3 4 thiadiazino 6 5 b indoles |
| topic | Jurnal i-lib UGM |
| work_keys_str_mv | AT perpustakaanugmilib sydnonederivativesasynthonsfornovelmesoioniccompoundssynthesischaracterizationandantimicrobialevaluationofsome24substitutedanilinosyndon3yl134thiadiazino65bindoles |