Production of a panel of monoclonal antibodies against the nucleocapsid protein of heat resistant Newcastle disease virus
A panel of six monoclonal antibodies against the nucleocapsid protein (NP) of Newcastle disease virus (NDV) strain AF2240 was produced by immunization of Balb/c mice with purified NP. Isotyping test revealed three of the monoclonal (mAbs) were IgG1 and the others were IgG2a. All of the mAbs recog...
Main Authors: | , , , , , |
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Format: | Proceeding Paper |
Language: | English |
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2007
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Online Access: | http://irep.iium.edu.my/29278/1/ICBioE_Paper_raha1%27_2007.pdf |
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author | Ahmad Raus, Raha Ali, Abdul Manaf Tan, Wen Siang Mohd. Salleh, Hamzah Eshagi, Majid Yusoff, Khatijah |
author_facet | Ahmad Raus, Raha Ali, Abdul Manaf Tan, Wen Siang Mohd. Salleh, Hamzah Eshagi, Majid Yusoff, Khatijah |
author_sort | Ahmad Raus, Raha |
collection | IIUM |
description | A panel of six monoclonal antibodies against the nucleocapsid protein
(NP) of Newcastle disease virus (NDV) strain AF2240 was produced by immunization of
Balb/c mice with purified NP. Isotyping test revealed three of the monoclonal (mAbs)
were IgG1 and the others were IgG2a. All of the mAbs recognized linearized NP
epitopes. The reactivity of these mAbs with local isolates revealed that three mAbs
recognized conserved antigenic sites and the others bind to antigenic sites which
undergone considerable changes. |
first_indexed | 2024-03-05T23:13:51Z |
format | Proceeding Paper |
id | oai:generic.eprints.org:29278 |
institution | International Islamic University Malaysia |
language | English |
last_indexed | 2024-03-05T23:13:51Z |
publishDate | 2007 |
record_format | dspace |
spelling | oai:generic.eprints.org:292782021-06-18T02:43:33Z http://irep.iium.edu.my/29278/ Production of a panel of monoclonal antibodies against the nucleocapsid protein of heat resistant Newcastle disease virus Ahmad Raus, Raha Ali, Abdul Manaf Tan, Wen Siang Mohd. Salleh, Hamzah Eshagi, Majid Yusoff, Khatijah Q Science (General) QR355 Virology SF Animal culture A panel of six monoclonal antibodies against the nucleocapsid protein (NP) of Newcastle disease virus (NDV) strain AF2240 was produced by immunization of Balb/c mice with purified NP. Isotyping test revealed three of the monoclonal (mAbs) were IgG1 and the others were IgG2a. All of the mAbs recognized linearized NP epitopes. The reactivity of these mAbs with local isolates revealed that three mAbs recognized conserved antigenic sites and the others bind to antigenic sites which undergone considerable changes. 2007 Proceeding Paper PeerReviewed application/pdf en http://irep.iium.edu.my/29278/1/ICBioE_Paper_raha1%27_2007.pdf Ahmad Raus, Raha and Ali, Abdul Manaf and Tan, Wen Siang and Mohd. Salleh, Hamzah and Eshagi, Majid and Yusoff, Khatijah (2007) Production of a panel of monoclonal antibodies against the nucleocapsid protein of heat resistant Newcastle disease virus. In: International Conference on Biotechnology Engineering (ICBioE’07), 8 - 10 May 2007, Kuala Lumpur. |
spellingShingle | Q Science (General) QR355 Virology SF Animal culture Ahmad Raus, Raha Ali, Abdul Manaf Tan, Wen Siang Mohd. Salleh, Hamzah Eshagi, Majid Yusoff, Khatijah Production of a panel of monoclonal antibodies against the nucleocapsid protein of heat resistant Newcastle disease virus |
title | Production of a panel of monoclonal antibodies against the nucleocapsid protein of heat resistant Newcastle disease virus |
title_full | Production of a panel of monoclonal antibodies against the nucleocapsid protein of heat resistant Newcastle disease virus |
title_fullStr | Production of a panel of monoclonal antibodies against the nucleocapsid protein of heat resistant Newcastle disease virus |
title_full_unstemmed | Production of a panel of monoclonal antibodies against the nucleocapsid protein of heat resistant Newcastle disease virus |
title_short | Production of a panel of monoclonal antibodies against the nucleocapsid protein of heat resistant Newcastle disease virus |
title_sort | production of a panel of monoclonal antibodies against the nucleocapsid protein of heat resistant newcastle disease virus |
topic | Q Science (General) QR355 Virology SF Animal culture |
url | http://irep.iium.edu.my/29278/1/ICBioE_Paper_raha1%27_2007.pdf |
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