β-Cyclodextrin conjugated magnetic, fluorescent silica core-shell nanoparticles for biomedical applications
We present synthesis of highly uniform magnetic nanocomposite material possessing an assortment of important functionalities: magnetism, luminescence, cell-targeting, and hydrophobic drug delivery. Magnetic particle Fe 3O4 is encapsulated within a shell of SiO2 that ensures biocompatibility of the n...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier Ltd.
2013
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/29307/1/shahab__%CE%B2-Cyclodextrin_1-s2.0-S0144861713001859-main.pdf |
| _version_ | 1825647189723971584 |
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| author | Md. Badruddoza , Abu Zayed Rahman , Md. Taifur Ghosh , Sudipa Hossain , Md. Zakir Shi , Jizhong Hidajat , Kus Uddin, Mohammad Shahab |
| author_facet | Md. Badruddoza , Abu Zayed Rahman , Md. Taifur Ghosh , Sudipa Hossain , Md. Zakir Shi , Jizhong Hidajat , Kus Uddin, Mohammad Shahab |
| author_sort | Md. Badruddoza , Abu Zayed |
| collection | IIUM |
| description | We present synthesis of highly uniform magnetic nanocomposite material possessing an assortment of important functionalities: magnetism, luminescence, cell-targeting, and hydrophobic drug delivery. Magnetic particle Fe 3O4 is encapsulated within a shell of SiO2 that ensures biocompatibility of the nanocomposite as well as act as a host for fluorescent dye (FITC), cancer-targeting ligand (folic acid), and a hydrophobic drug storage-delivering vehicle (β-cyclodextrin). Our preliminary results suggest that such core-shell nanocomposite can be a smart theranostic candidate for simultaneous fluorescence imaging, magnetic manipulation, cancer cell-targeting and hydrophobic drug delivery. |
| first_indexed | 2024-03-05T23:13:55Z |
| format | Article |
| id | oai:generic.eprints.org:29307 |
| institution | International Islamic University Malaysia |
| language | English |
| last_indexed | 2024-03-13T19:10:10Z |
| publishDate | 2013 |
| publisher | Elsevier Ltd. |
| record_format | dspace |
| spelling | oai:generic.eprints.org:293072014-02-14T03:05:31Z http://irep.iium.edu.my/29307/ β-Cyclodextrin conjugated magnetic, fluorescent silica core-shell nanoparticles for biomedical applications Md. Badruddoza , Abu Zayed Rahman , Md. Taifur Ghosh , Sudipa Hossain , Md. Zakir Shi , Jizhong Hidajat , Kus Uddin, Mohammad Shahab TP155 Chemical engineering TP248.13 Biotechnology We present synthesis of highly uniform magnetic nanocomposite material possessing an assortment of important functionalities: magnetism, luminescence, cell-targeting, and hydrophobic drug delivery. Magnetic particle Fe 3O4 is encapsulated within a shell of SiO2 that ensures biocompatibility of the nanocomposite as well as act as a host for fluorescent dye (FITC), cancer-targeting ligand (folic acid), and a hydrophobic drug storage-delivering vehicle (β-cyclodextrin). Our preliminary results suggest that such core-shell nanocomposite can be a smart theranostic candidate for simultaneous fluorescence imaging, magnetic manipulation, cancer cell-targeting and hydrophobic drug delivery. Elsevier Ltd. 2013-06-05 Article PeerReviewed application/pdf en http://irep.iium.edu.my/29307/1/shahab__%CE%B2-Cyclodextrin_1-s2.0-S0144861713001859-main.pdf Md. Badruddoza , Abu Zayed and Rahman , Md. Taifur and Ghosh , Sudipa and Hossain , Md. Zakir and Shi , Jizhong and Hidajat , Kus and Uddin, Mohammad Shahab (2013) β-Cyclodextrin conjugated magnetic, fluorescent silica core-shell nanoparticles for biomedical applications. Carbohydrate Polymers, 95 (1). pp. 449-457. ISSN 0144-8617 (O) 10.1016/j.carbpol.2013.02.046 |
| spellingShingle | TP155 Chemical engineering TP248.13 Biotechnology Md. Badruddoza , Abu Zayed Rahman , Md. Taifur Ghosh , Sudipa Hossain , Md. Zakir Shi , Jizhong Hidajat , Kus Uddin, Mohammad Shahab β-Cyclodextrin conjugated magnetic, fluorescent silica core-shell nanoparticles for biomedical applications |
| title | β-Cyclodextrin conjugated magnetic, fluorescent silica core-shell nanoparticles for biomedical applications
|
| title_full | β-Cyclodextrin conjugated magnetic, fluorescent silica core-shell nanoparticles for biomedical applications
|
| title_fullStr | β-Cyclodextrin conjugated magnetic, fluorescent silica core-shell nanoparticles for biomedical applications
|
| title_full_unstemmed | β-Cyclodextrin conjugated magnetic, fluorescent silica core-shell nanoparticles for biomedical applications
|
| title_short | β-Cyclodextrin conjugated magnetic, fluorescent silica core-shell nanoparticles for biomedical applications
|
| title_sort | β cyclodextrin conjugated magnetic fluorescent silica core shell nanoparticles for biomedical applications |
| topic | TP155 Chemical engineering TP248.13 Biotechnology |
| url | http://irep.iium.edu.my/29307/1/shahab__%CE%B2-Cyclodextrin_1-s2.0-S0144861713001859-main.pdf |
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