A scanning electron microscopic study on the transitional mucosa of the distal colorectal carcinoma
Colorectal cancer was ranked the most common cancer among males and second most common cancer among females in Peninsular Malaysia (Malaysian cancer statistics, 2006). The transitional mucosa (TM) was apparently normal in histological section but abnormal in mucin histochemistry of large intestina...
| Main Authors: | , , , |
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| Format: | Proceeding Paper |
| Language: | English English |
| Published: |
2013
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/29731/1/IRIE_2013_YT.pdf http://irep.iium.edu.my/29731/4/A_scanning_electron_microscopic_study_on_the_transitional.pdf |
| Summary: | Colorectal cancer was ranked the most common cancer among males and second most common cancer among
females in Peninsular Malaysia (Malaysian cancer statistics, 2006). The transitional mucosa (TM) was apparently
normal in histological section but abnormal in mucin histochemistry of large intestinal mucosa immediately adjacent
to colorectal adenocarcinoma (Filipe, 1969). The aim of this study was to determine the length of transitional
mucosa(cut-off score) in Malaysian with distal colorectal cancer. The distal colon comprises of the descending
colon, sigmoid colon and the rectum. The study group included ten normal control patients and ten patients with
rectosigmoid tumor. Three samples were taken from each resected rectosigmoid carcinoma specimen( 2, 5, and 10
cms from the proximal margin of the carcinoma). Forty specimen were processed and viewed the mucosal surface
under scanning electron microscope(SEM). The mean length of TM was 7.6cm. There was no statistically
significant association between age, gender, race, site of tumor, differentiation of tumor and clinical staging with
that of the TM changes(pvalue=> 0.05). In conclusion there was longer length of TM changes in this study. |
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