Outcome of surgical treatment of pelvic osteosarcoma : Hospital Universiti Sains Malaysia experience

We reviewed the surgical treatment and outcomes of 13 patients with pelvic osteosarcoma treated in our centre in the past decade. The study sample included 9 males and 4 females with a mean age of 28.1 years. Four patients had ileal lesions, five had acetabulum lesions, one had a ischiopubis lesion,...

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Main Authors: Sharifudin, Mohd Ariff, Wan, Zulmi, Wan Ismail, Wan Faisham Numan, Mat Zin, Nor Azman, Mohamed Amir, Nawaz Hussain
Format: Article
Language:English
Published: Malaysian Orthopaedic Association 2013
Subjects:
Online Access:http://irep.iium.edu.my/29811/1/pelvic-osteosarcoma.pdf
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author Sharifudin, Mohd Ariff
Wan, Zulmi
Wan Ismail, Wan Faisham Numan
Mat Zin, Nor Azman
Mohamed Amir, Nawaz Hussain
author_facet Sharifudin, Mohd Ariff
Wan, Zulmi
Wan Ismail, Wan Faisham Numan
Mat Zin, Nor Azman
Mohamed Amir, Nawaz Hussain
author_sort Sharifudin, Mohd Ariff
collection IIUM
description We reviewed the surgical treatment and outcomes of 13 patients with pelvic osteosarcoma treated in our centre in the past decade. The study sample included 9 males and 4 females with a mean age of 28.1 years. Four patients had ileal lesions, five had acetabulum lesions, one had a ischiopubis lesion, and three had involvement of the whole hemipelvis. Seven patients presented with distant metastases at diagnosis. Limb salvage was performed in 6 patients and amputation in 7. In 60% of cases in the limb salvage surgery group, we attempted wide resection with positive microscopic margin compared to only 16.7% in the amputation group. Local recurrence was higher in the limb salvage group. Overall survival was 18 months for mean follow up of 14.8 months. Median survival was 19 months in the limb salvage group compared to 9 months in amputation group. The outcome of surgical treatment of pelvic osteosarcoma remains poor despite advancements in musculoskeletal oncology treatment.
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spelling oai:generic.eprints.org:298112015-11-16T07:03:42Z http://irep.iium.edu.my/29811/ Outcome of surgical treatment of pelvic osteosarcoma : Hospital Universiti Sains Malaysia experience Sharifudin, Mohd Ariff Wan, Zulmi Wan Ismail, Wan Faisham Numan Mat Zin, Nor Azman Mohamed Amir, Nawaz Hussain RB Pathology RC254 Neoplasms. Tumors. Oncology (including Cancer) RD701 Orthopedics We reviewed the surgical treatment and outcomes of 13 patients with pelvic osteosarcoma treated in our centre in the past decade. The study sample included 9 males and 4 females with a mean age of 28.1 years. Four patients had ileal lesions, five had acetabulum lesions, one had a ischiopubis lesion, and three had involvement of the whole hemipelvis. Seven patients presented with distant metastases at diagnosis. Limb salvage was performed in 6 patients and amputation in 7. In 60% of cases in the limb salvage surgery group, we attempted wide resection with positive microscopic margin compared to only 16.7% in the amputation group. Local recurrence was higher in the limb salvage group. Overall survival was 18 months for mean follow up of 14.8 months. Median survival was 19 months in the limb salvage group compared to 9 months in amputation group. The outcome of surgical treatment of pelvic osteosarcoma remains poor despite advancements in musculoskeletal oncology treatment. Malaysian Orthopaedic Association 2013-03 Article PeerReviewed application/pdf en http://irep.iium.edu.my/29811/1/pelvic-osteosarcoma.pdf Sharifudin, Mohd Ariff and Wan, Zulmi and Wan Ismail, Wan Faisham Numan and Mat Zin, Nor Azman and Mohamed Amir, Nawaz Hussain (2013) Outcome of surgical treatment of pelvic osteosarcoma : Hospital Universiti Sains Malaysia experience. Malaysian Orthopaedic Journal, 7 (1). pp. 56-62. ISSN 1985-2533 http://www.morthoj.org/2013/v7n1/pelvic-osteosarcoma.pdf http://dx.doi.org/10.5704.MOJ.1303.018
spellingShingle RB Pathology
RC254 Neoplasms. Tumors. Oncology (including Cancer)
RD701 Orthopedics
Sharifudin, Mohd Ariff
Wan, Zulmi
Wan Ismail, Wan Faisham Numan
Mat Zin, Nor Azman
Mohamed Amir, Nawaz Hussain
Outcome of surgical treatment of pelvic osteosarcoma : Hospital Universiti Sains Malaysia experience
title Outcome of surgical treatment of pelvic osteosarcoma : Hospital Universiti Sains Malaysia experience
title_full Outcome of surgical treatment of pelvic osteosarcoma : Hospital Universiti Sains Malaysia experience
title_fullStr Outcome of surgical treatment of pelvic osteosarcoma : Hospital Universiti Sains Malaysia experience
title_full_unstemmed Outcome of surgical treatment of pelvic osteosarcoma : Hospital Universiti Sains Malaysia experience
title_short Outcome of surgical treatment of pelvic osteosarcoma : Hospital Universiti Sains Malaysia experience
title_sort outcome of surgical treatment of pelvic osteosarcoma hospital universiti sains malaysia experience
topic RB Pathology
RC254 Neoplasms. Tumors. Oncology (including Cancer)
RD701 Orthopedics
url http://irep.iium.edu.my/29811/1/pelvic-osteosarcoma.pdf
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