Mechanical loading response in trabecular bone is abrogated by sclerostin - A direct demonstration
Sclerostin is expressed almost exclusively by mature osteocytes in bone. Recent findings from this lab indicate that sclerostin targets pre-osteocytes and osteocytes to regulate bone mineralisation(1), osteoclast activity(2), and, potentially, osteocytic osteolysis(3). Sclerostin expression in vivo...
| Main Authors: | , , , , |
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| Format: | Proceeding Paper |
| Language: | English English English |
| Published: |
Australian Health and Medical Research Council
2012
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/29838/17/29838%20-abstract.PDF http://irep.iium.edu.my/29838/1/AHMRC_2012_Poster_Kamarul_Final.pdf http://irep.iium.edu.my/29838/2/AHMRC_2012_Kamarul_Final.pdf |