Discrimination of Alternanthera sessilis of different origins in Malaysia using FT-IR and two-dimensional infrared correlation spectroscopy and multivariate data analysis

Alternanthera sessilis is one of the herbal medicines used in Malaysia especially among Chinese race. The metabolite fingerprinting analysis of ethanolic extracts of leaves of A.sessilis was carried out using Fourier-transform infrared (FTIR) spectroscopy in combination with multivariate data analys...

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Main Authors: Razak , Siti Shahrul Nazifah, Abdaziz, Siti Mutheerah, Radu, Son, Abas, Faridah, Neto, Viktor, Khatib, Alfi
Format: Proceeding Paper
Language:English
English
English
Published: 2013
Subjects:
Online Access:http://irep.iium.edu.my/31368/1/242TOPROCJ.htm
http://irep.iium.edu.my/31368/3/proceeding1.pdf
http://irep.iium.edu.my/31368/4/Razak_et_al._1.pdf
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author Razak , Siti Shahrul Nazifah
Abdaziz, Siti Mutheerah
Radu, Son
Abas, Faridah
Neto, Viktor
Khatib, Alfi
author_facet Razak , Siti Shahrul Nazifah
Abdaziz, Siti Mutheerah
Radu, Son
Abas, Faridah
Neto, Viktor
Khatib, Alfi
author_sort Razak , Siti Shahrul Nazifah
collection IIUM
description Alternanthera sessilis is one of the herbal medicines used in Malaysia especially among Chinese race. The metabolite fingerprinting analysis of ethanolic extracts of leaves of A.sessilis was carried out using Fourier-transform infrared (FTIR) spectroscopy in combination with multivariate data analysis to differentiate between four different origins of plant harvested. Principle component analysis (PCA) of the infrared spectra showed an obvious cluster between origin 1(from Putrajaya) and origin 3 (from Rantau Panjang), meanwhile, origin 2 (from Serdang) and 4 (from Ampang) is almost closer by PC1 and PC2 (99.2% and 0.4% total variance, respectively) score plots. The results of PLS-DA similar with the PCA result. The samples were further analyzed using two-dimensional infrared correlation spectroscopy and the results showed remarkable differences between samples of different origins.
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spelling oai:generic.eprints.org:313682013-12-16T04:36:30Z http://irep.iium.edu.my/31368/ Discrimination of Alternanthera sessilis of different origins in Malaysia using FT-IR and two-dimensional infrared correlation spectroscopy and multivariate data analysis Razak , Siti Shahrul Nazifah Abdaziz, Siti Mutheerah Radu, Son Abas, Faridah Neto, Viktor Khatib, Alfi QD Chemistry Alternanthera sessilis is one of the herbal medicines used in Malaysia especially among Chinese race. The metabolite fingerprinting analysis of ethanolic extracts of leaves of A.sessilis was carried out using Fourier-transform infrared (FTIR) spectroscopy in combination with multivariate data analysis to differentiate between four different origins of plant harvested. Principle component analysis (PCA) of the infrared spectra showed an obvious cluster between origin 1(from Putrajaya) and origin 3 (from Rantau Panjang), meanwhile, origin 2 (from Serdang) and 4 (from Ampang) is almost closer by PC1 and PC2 (99.2% and 0.4% total variance, respectively) score plots. The results of PLS-DA similar with the PCA result. The samples were further analyzed using two-dimensional infrared correlation spectroscopy and the results showed remarkable differences between samples of different origins. 2013-03-06 Proceeding Paper PeerReviewed application/pdf en http://irep.iium.edu.my/31368/1/242TOPROCJ.htm application/pdf en http://irep.iium.edu.my/31368/3/proceeding1.pdf application/pdf en http://irep.iium.edu.my/31368/4/Razak_et_al._1.pdf Razak , Siti Shahrul Nazifah and Abdaziz, Siti Mutheerah and Radu, Son and Abas, Faridah and Neto, Viktor and Khatib, Alfi (2013) Discrimination of Alternanthera sessilis of different origins in Malaysia using FT-IR and two-dimensional infrared correlation spectroscopy and multivariate data analysis. In: International Conference on Natural Products 2013 (ICNP 2013), 4-6 Mar 2013, Shah Alam. http://www.benthamscience.com/open/toprocj/articles/V004/242TOPROCJ.htm
spellingShingle QD Chemistry
Razak , Siti Shahrul Nazifah
Abdaziz, Siti Mutheerah
Radu, Son
Abas, Faridah
Neto, Viktor
Khatib, Alfi
Discrimination of Alternanthera sessilis of different origins in Malaysia using FT-IR and two-dimensional infrared correlation spectroscopy and multivariate data analysis
title Discrimination of Alternanthera sessilis of different origins in Malaysia using FT-IR and two-dimensional infrared correlation spectroscopy and multivariate data analysis
title_full Discrimination of Alternanthera sessilis of different origins in Malaysia using FT-IR and two-dimensional infrared correlation spectroscopy and multivariate data analysis
title_fullStr Discrimination of Alternanthera sessilis of different origins in Malaysia using FT-IR and two-dimensional infrared correlation spectroscopy and multivariate data analysis
title_full_unstemmed Discrimination of Alternanthera sessilis of different origins in Malaysia using FT-IR and two-dimensional infrared correlation spectroscopy and multivariate data analysis
title_short Discrimination of Alternanthera sessilis of different origins in Malaysia using FT-IR and two-dimensional infrared correlation spectroscopy and multivariate data analysis
title_sort discrimination of alternanthera sessilis of different origins in malaysia using ft ir and two dimensional infrared correlation spectroscopy and multivariate data analysis
topic QD Chemistry
url http://irep.iium.edu.my/31368/1/242TOPROCJ.htm
http://irep.iium.edu.my/31368/3/proceeding1.pdf
http://irep.iium.edu.my/31368/4/Razak_et_al._1.pdf
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