The impact of intrapartum pethidine on the neonatal outcome: a perspective review

Objective: To study the effect of intrapartum pethidine administration on the fetal heart rate pattern and neonatal outcome. Method: This is a prospective observational study done on forty low risk uncomplicated pregnancy at term in the first stage of labour. The study was done in the labour suite...

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Main Authors: Husin, Roziah, Abdulwahab, Dalia F, BR, Rukaiah, Ismail, Rozihan
Format: Proceeding Paper
Language:English
English
Published: 2012
Subjects:
Online Access:http://irep.iium.edu.my/32077/2/rcog_pethidine_poster_%281%29.pdf
http://irep.iium.edu.my/32077/5/Dear_dr_roziah_%281%29_DrDalia.pdf
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author Husin, Roziah
Abdulwahab, Dalia F
BR, Rukaiah
Ismail, Rozihan
author_facet Husin, Roziah
Abdulwahab, Dalia F
BR, Rukaiah
Ismail, Rozihan
author_sort Husin, Roziah
collection IIUM
description Objective: To study the effect of intrapartum pethidine administration on the fetal heart rate pattern and neonatal outcome. Method: This is a prospective observational study done on forty low risk uncomplicated pregnancy at term in the first stage of labour. The study was done in the labour suite in Hospital Tengku Ampuan Afzan Kuantan, Malaysia. Intramuscular Pethidine 1mg/kg was given as intrapartum analgesia to all consented patient with normal baseline fetal heart rate and clear liquor. Intrapartum fetal heart rate pattern and neonatal outcome were reviewed and analysed by SSPS 17.0. Results: Total of 40 patients recruited in this study with mean age of 27.9 ± 6.03 years and mean gestational age of 39.0 ± 0.81 weeks. The mean duration from pethidine administration to delivery is 285.5 ± 178.9 minutes (4 hours and 45 minutes). Out of 40 patients, 2 (5%) cases had suspicious CTG 1 hour post pethidine administration, first one with absence of acceleration and the second with early deceleration which lasted for 45 minutes and one hour respectively. All neonates delivered with good Apgar Score, 8 at 1 minute and 9 at 5 minute. A total of 9 (22.5%) cases were admitted to the Neonatal Intensive Care Unit (NICU). Seven (17.5%) cases were admitted for observation because of delivery less than 4 hours after pethidine administration, following the neonatal protocol at our centre. Two (5%) cases were admitted for G6PD. Neither required ventilation nor antidotes. All of them were discharged to mother after 24 hours apart from those admitted because of G6PD. Conclusion: Intrapartum pethidine is still an analgesic option which is simple, cheap and easily available without major effect to the fetal heart rate pattern and the neonatal outcome.
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spelling oai:generic.eprints.org:320772013-09-19T08:31:17Z http://irep.iium.edu.my/32077/ The impact of intrapartum pethidine on the neonatal outcome: a perspective review Husin, Roziah Abdulwahab, Dalia F BR, Rukaiah Ismail, Rozihan RG Gynecology and obstetrics Objective: To study the effect of intrapartum pethidine administration on the fetal heart rate pattern and neonatal outcome. Method: This is a prospective observational study done on forty low risk uncomplicated pregnancy at term in the first stage of labour. The study was done in the labour suite in Hospital Tengku Ampuan Afzan Kuantan, Malaysia. Intramuscular Pethidine 1mg/kg was given as intrapartum analgesia to all consented patient with normal baseline fetal heart rate and clear liquor. Intrapartum fetal heart rate pattern and neonatal outcome were reviewed and analysed by SSPS 17.0. Results: Total of 40 patients recruited in this study with mean age of 27.9 ± 6.03 years and mean gestational age of 39.0 ± 0.81 weeks. The mean duration from pethidine administration to delivery is 285.5 ± 178.9 minutes (4 hours and 45 minutes). Out of 40 patients, 2 (5%) cases had suspicious CTG 1 hour post pethidine administration, first one with absence of acceleration and the second with early deceleration which lasted for 45 minutes and one hour respectively. All neonates delivered with good Apgar Score, 8 at 1 minute and 9 at 5 minute. A total of 9 (22.5%) cases were admitted to the Neonatal Intensive Care Unit (NICU). Seven (17.5%) cases were admitted for observation because of delivery less than 4 hours after pethidine administration, following the neonatal protocol at our centre. Two (5%) cases were admitted for G6PD. Neither required ventilation nor antidotes. All of them were discharged to mother after 24 hours apart from those admitted because of G6PD. Conclusion: Intrapartum pethidine is still an analgesic option which is simple, cheap and easily available without major effect to the fetal heart rate pattern and the neonatal outcome. 2012-06 Proceeding Paper PeerReviewed application/pdf en http://irep.iium.edu.my/32077/2/rcog_pethidine_poster_%281%29.pdf application/pdf en http://irep.iium.edu.my/32077/5/Dear_dr_roziah_%281%29_DrDalia.pdf Husin, Roziah and Abdulwahab, Dalia F and BR, Rukaiah and Ismail, Rozihan (2012) The impact of intrapartum pethidine on the neonatal outcome: a perspective review. In: 10th International Scientific Congress of the Royal College of Obstetricians and Gynaecologists, 5-8th June 2012, Kuching, Sarawak.
spellingShingle RG Gynecology and obstetrics
Husin, Roziah
Abdulwahab, Dalia F
BR, Rukaiah
Ismail, Rozihan
The impact of intrapartum pethidine on the neonatal outcome: a perspective review
title The impact of intrapartum pethidine on the neonatal outcome: a perspective review
title_full The impact of intrapartum pethidine on the neonatal outcome: a perspective review
title_fullStr The impact of intrapartum pethidine on the neonatal outcome: a perspective review
title_full_unstemmed The impact of intrapartum pethidine on the neonatal outcome: a perspective review
title_short The impact of intrapartum pethidine on the neonatal outcome: a perspective review
title_sort impact of intrapartum pethidine on the neonatal outcome a perspective review
topic RG Gynecology and obstetrics
url http://irep.iium.edu.my/32077/2/rcog_pethidine_poster_%281%29.pdf
http://irep.iium.edu.my/32077/5/Dear_dr_roziah_%281%29_DrDalia.pdf
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