Assessment of cytotoxicity and toxicity for phosphonium-based deep eutectic solvents
In this work, the cytotoxicity and toxicity of phosphonium-based deep eutectic solvents (DESs) with three hydrogen bond donors, namely glycerine, ethylene glycol, and triethylene glycol were investigated. The cytotoxicity effect was tested using brine shrimp (Artemia salina). The toxicity was inve...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier Inc.
2013
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| Online Access: | http://irep.iium.edu.my/32301/1/Assessment_of_cytotoxicity.pdf |
| _version_ | 1796878237304881152 |
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| author | Hayyan, Maan Hashim, Mohd. Ali Al-Saadi, Mohammed A. Hayyan, Adeeb Alnashef, Inas Muen Mirghani, Mohamed Elwathig Saeed |
| author_facet | Hayyan, Maan Hashim, Mohd. Ali Al-Saadi, Mohammed A. Hayyan, Adeeb Alnashef, Inas Muen Mirghani, Mohamed Elwathig Saeed |
| author_sort | Hayyan, Maan |
| collection | IIUM |
| description | In this work, the cytotoxicity and toxicity of phosphonium-based deep eutectic solvents (DESs) with three
hydrogen bond donors, namely glycerine, ethylene glycol, and triethylene glycol were investigated. The
cytotoxicity effect was tested using brine shrimp (Artemia salina). The toxicity was investigated using the two Gram positive bacteria Bacillus subtilis and Staphylococcus aureus, and two Gram negative bacteria Escherichia coli and Pseudomonas aeruginosa. The cytotoxicity of tested DESs was much higher than that of their individual components, indicating their toxicological behavior was different. It was also found that there was toxic effect on the studied bacteria, indicating their potential application as anti-bacterial agents. To the best of our knowledge, this is the first time the cytotoxicity and toxicity of phosphoniumbased DESs were studied. |
| first_indexed | 2024-03-05T23:18:38Z |
| format | Article |
| id | oai:generic.eprints.org:32301 |
| institution | International Islamic University Malaysia |
| language | English |
| last_indexed | 2024-03-05T23:18:38Z |
| publishDate | 2013 |
| publisher | Elsevier Inc. |
| record_format | dspace |
| spelling | oai:generic.eprints.org:323012015-03-16T02:29:43Z http://irep.iium.edu.my/32301/ Assessment of cytotoxicity and toxicity for phosphonium-based deep eutectic solvents Hayyan, Maan Hashim, Mohd. Ali Al-Saadi, Mohammed A. Hayyan, Adeeb Alnashef, Inas Muen Mirghani, Mohamed Elwathig Saeed T Technology (General) In this work, the cytotoxicity and toxicity of phosphonium-based deep eutectic solvents (DESs) with three hydrogen bond donors, namely glycerine, ethylene glycol, and triethylene glycol were investigated. The cytotoxicity effect was tested using brine shrimp (Artemia salina). The toxicity was investigated using the two Gram positive bacteria Bacillus subtilis and Staphylococcus aureus, and two Gram negative bacteria Escherichia coli and Pseudomonas aeruginosa. The cytotoxicity of tested DESs was much higher than that of their individual components, indicating their toxicological behavior was different. It was also found that there was toxic effect on the studied bacteria, indicating their potential application as anti-bacterial agents. To the best of our knowledge, this is the first time the cytotoxicity and toxicity of phosphoniumbased DESs were studied. Elsevier Inc. 2013-09-02 Article PeerReviewed application/pdf en http://irep.iium.edu.my/32301/1/Assessment_of_cytotoxicity.pdf Hayyan, Maan and Hashim, Mohd. Ali and Al-Saadi, Mohammed A. and Hayyan, Adeeb and Alnashef, Inas Muen and Mirghani, Mohamed Elwathig Saeed (2013) Assessment of cytotoxicity and toxicity for phosphonium-based deep eutectic solvents. Chemosphere, 93 (2). pp. 455-459. ISSN 0045-6535 http://www.sciencedirect.com/science/article/pii/S0045653513007480# 10.1016/j.chemosphere.2013.05.013 |
| spellingShingle | T Technology (General) Hayyan, Maan Hashim, Mohd. Ali Al-Saadi, Mohammed A. Hayyan, Adeeb Alnashef, Inas Muen Mirghani, Mohamed Elwathig Saeed Assessment of cytotoxicity and toxicity for phosphonium-based deep eutectic solvents |
| title | Assessment of cytotoxicity and toxicity for phosphonium-based deep eutectic solvents |
| title_full | Assessment of cytotoxicity and toxicity for phosphonium-based deep eutectic solvents |
| title_fullStr | Assessment of cytotoxicity and toxicity for phosphonium-based deep eutectic solvents |
| title_full_unstemmed | Assessment of cytotoxicity and toxicity for phosphonium-based deep eutectic solvents |
| title_short | Assessment of cytotoxicity and toxicity for phosphonium-based deep eutectic solvents |
| title_sort | assessment of cytotoxicity and toxicity for phosphonium based deep eutectic solvents |
| topic | T Technology (General) |
| url | http://irep.iium.edu.my/32301/1/Assessment_of_cytotoxicity.pdf |
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