Synthesise and 2-Deoxyribose Degradation Inhibition of Two Benzalacetone Derivatives
Two benzalacetones deivatives - Le. 3-hydroxyben/alacetone and 4-hydroxy-3-methoxybenzalacetone -have been synthesized and its antioxidant activity have also been tested. Synthesize were done through cross aldol condensation reaction under basic condition using ethanol as solvent. Re-crystailization...
| Main Authors: | , , , |
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| Format: | Conference or Workshop Item |
| Language: | English |
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2010
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| Online Access: | https://repository.ugm.ac.id/32879/1/Synthesise_and_2-Deoxyribose_Degradation_Inhibition_of_Two_Benzalacetone_Derivatives.pdf |
| _version_ | 1826033489305141248 |
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| author | Handayani, Sri Matsjeh, Sabirin Anwar, Chairil Atun, Sri |
| author_facet | Handayani, Sri Matsjeh, Sabirin Anwar, Chairil Atun, Sri |
| author_sort | Handayani, Sri |
| collection | UGM |
| description | Two benzalacetones deivatives - Le. 3-hydroxyben/alacetone and 4-hydroxy-3-methoxybenzalacetone -have been synthesized and its antioxidant activity have also been tested. Synthesize were done through cross aldol condensation reaction under basic condition using ethanol as solvent. Re-crystailization using methanol was used to obtain pure material, which were yielding 50.62% of 3-hydroxybenzalacetone and 52.38% of 4-hydroxy-3-methoxvbenzalacetone. Resulting materials have been characterized by TLC, H1K, and NMR spectrometer. The activity tested performed with Deoxyibose assay. 3-hydroxibenzalacetone has higher antioxidant activity than 4-hydroxy-3-methoxybenzalacetone, which 3-hydroxybcnzalacetone more active inhibited 2-Deoxyribose degradation than 4-hydroxy-3-methoxybenzalacetone |
| first_indexed | 2024-03-05T23:19:44Z |
| format | Conference or Workshop Item |
| id | oai:generic.eprints.org:32879 |
| institution | Universiti Gadjah Mada |
| language | English |
| last_indexed | 2024-03-13T19:12:09Z |
| publishDate | 2010 |
| record_format | dspace |
| spelling | oai:generic.eprints.org:328792014-03-07T05:53:40Z https://repository.ugm.ac.id/32879/ Synthesise and 2-Deoxyribose Degradation Inhibition of Two Benzalacetone Derivatives Handayani, Sri Matsjeh, Sabirin Anwar, Chairil Atun, Sri Makalah Seminar Two benzalacetones deivatives - Le. 3-hydroxyben/alacetone and 4-hydroxy-3-methoxybenzalacetone -have been synthesized and its antioxidant activity have also been tested. Synthesize were done through cross aldol condensation reaction under basic condition using ethanol as solvent. Re-crystailization using methanol was used to obtain pure material, which were yielding 50.62% of 3-hydroxybenzalacetone and 52.38% of 4-hydroxy-3-methoxvbenzalacetone. Resulting materials have been characterized by TLC, H1K, and NMR spectrometer. The activity tested performed with Deoxyibose assay. 3-hydroxibenzalacetone has higher antioxidant activity than 4-hydroxy-3-methoxybenzalacetone, which 3-hydroxybcnzalacetone more active inhibited 2-Deoxyribose degradation than 4-hydroxy-3-methoxybenzalacetone 2010 Conference or Workshop Item PeerReviewed application/pdf en https://repository.ugm.ac.id/32879/1/Synthesise_and_2-Deoxyribose_Degradation_Inhibition_of_Two_Benzalacetone_Derivatives.pdf Handayani, Sri and Matsjeh, Sabirin and Anwar, Chairil and Atun, Sri (2010) Synthesise and 2-Deoxyribose Degradation Inhibition of Two Benzalacetone Derivatives. In: The 4nd Indonesia Japan Joint Scientific Symposium 2010. |
| spellingShingle | Makalah Seminar Handayani, Sri Matsjeh, Sabirin Anwar, Chairil Atun, Sri Synthesise and 2-Deoxyribose Degradation Inhibition of Two Benzalacetone Derivatives |
| title | Synthesise and 2-Deoxyribose Degradation Inhibition of Two Benzalacetone Derivatives |
| title_full | Synthesise and 2-Deoxyribose Degradation Inhibition of Two Benzalacetone Derivatives |
| title_fullStr | Synthesise and 2-Deoxyribose Degradation Inhibition of Two Benzalacetone Derivatives |
| title_full_unstemmed | Synthesise and 2-Deoxyribose Degradation Inhibition of Two Benzalacetone Derivatives |
| title_short | Synthesise and 2-Deoxyribose Degradation Inhibition of Two Benzalacetone Derivatives |
| title_sort | synthesise and 2 deoxyribose degradation inhibition of two benzalacetone derivatives |
| topic | Makalah Seminar |
| url | https://repository.ugm.ac.id/32879/1/Synthesise_and_2-Deoxyribose_Degradation_Inhibition_of_Two_Benzalacetone_Derivatives.pdf |
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