Synthesise and 2-Deoxyribose Degradation Inhibition of Two Benzalacetone Derivatives

Two benzalacetones deivatives - Le. 3-hydroxyben/alacetone and 4-hydroxy-3-methoxybenzalacetone -have been synthesized and its antioxidant activity have also been tested. Synthesize were done through cross aldol condensation reaction under basic condition using ethanol as solvent. Re-crystailization...

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Main Authors: Handayani, Sri, Matsjeh, Sabirin, Anwar, Chairil, Atun, Sri
Format: Conference or Workshop Item
Language:English
Published: 2010
Subjects:
Online Access:https://repository.ugm.ac.id/32879/1/Synthesise_and_2-Deoxyribose_Degradation_Inhibition_of_Two_Benzalacetone_Derivatives.pdf
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author Handayani, Sri
Matsjeh, Sabirin
Anwar, Chairil
Atun, Sri
author_facet Handayani, Sri
Matsjeh, Sabirin
Anwar, Chairil
Atun, Sri
author_sort Handayani, Sri
collection UGM
description Two benzalacetones deivatives - Le. 3-hydroxyben/alacetone and 4-hydroxy-3-methoxybenzalacetone -have been synthesized and its antioxidant activity have also been tested. Synthesize were done through cross aldol condensation reaction under basic condition using ethanol as solvent. Re-crystailization using methanol was used to obtain pure material, which were yielding 50.62% of 3-hydroxybenzalacetone and 52.38% of 4-hydroxy-3-methoxvbenzalacetone. Resulting materials have been characterized by TLC, H1K, and NMR spectrometer. The activity tested performed with Deoxyibose assay. 3-hydroxibenzalacetone has higher antioxidant activity than 4-hydroxy-3-methoxybenzalacetone, which 3-hydroxybcnzalacetone more active inhibited 2-Deoxyribose degradation than 4-hydroxy-3-methoxybenzalacetone
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spelling oai:generic.eprints.org:328792014-03-07T05:53:40Z https://repository.ugm.ac.id/32879/ Synthesise and 2-Deoxyribose Degradation Inhibition of Two Benzalacetone Derivatives Handayani, Sri Matsjeh, Sabirin Anwar, Chairil Atun, Sri Makalah Seminar Two benzalacetones deivatives - Le. 3-hydroxyben/alacetone and 4-hydroxy-3-methoxybenzalacetone -have been synthesized and its antioxidant activity have also been tested. Synthesize were done through cross aldol condensation reaction under basic condition using ethanol as solvent. Re-crystailization using methanol was used to obtain pure material, which were yielding 50.62% of 3-hydroxybenzalacetone and 52.38% of 4-hydroxy-3-methoxvbenzalacetone. Resulting materials have been characterized by TLC, H1K, and NMR spectrometer. The activity tested performed with Deoxyibose assay. 3-hydroxibenzalacetone has higher antioxidant activity than 4-hydroxy-3-methoxybenzalacetone, which 3-hydroxybcnzalacetone more active inhibited 2-Deoxyribose degradation than 4-hydroxy-3-methoxybenzalacetone 2010 Conference or Workshop Item PeerReviewed application/pdf en https://repository.ugm.ac.id/32879/1/Synthesise_and_2-Deoxyribose_Degradation_Inhibition_of_Two_Benzalacetone_Derivatives.pdf Handayani, Sri and Matsjeh, Sabirin and Anwar, Chairil and Atun, Sri (2010) Synthesise and 2-Deoxyribose Degradation Inhibition of Two Benzalacetone Derivatives. In: The 4nd Indonesia Japan Joint Scientific Symposium 2010.
spellingShingle Makalah Seminar
Handayani, Sri
Matsjeh, Sabirin
Anwar, Chairil
Atun, Sri
Synthesise and 2-Deoxyribose Degradation Inhibition of Two Benzalacetone Derivatives
title Synthesise and 2-Deoxyribose Degradation Inhibition of Two Benzalacetone Derivatives
title_full Synthesise and 2-Deoxyribose Degradation Inhibition of Two Benzalacetone Derivatives
title_fullStr Synthesise and 2-Deoxyribose Degradation Inhibition of Two Benzalacetone Derivatives
title_full_unstemmed Synthesise and 2-Deoxyribose Degradation Inhibition of Two Benzalacetone Derivatives
title_short Synthesise and 2-Deoxyribose Degradation Inhibition of Two Benzalacetone Derivatives
title_sort synthesise and 2 deoxyribose degradation inhibition of two benzalacetone derivatives
topic Makalah Seminar
url https://repository.ugm.ac.id/32879/1/Synthesise_and_2-Deoxyribose_Degradation_Inhibition_of_Two_Benzalacetone_Derivatives.pdf
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