The effect of prenatal administration of lead acetate on the morphology of epididymal and testicular spermatozoa in offspring mature male mice
The aims of this study were to assess the differences in the percentages of abnormal morphology between the epididymal and testicular spermatozoa of mature male offspring mice whose mothers were injected with various doses of lead acetate during gestation. Seventy two healthy female mice were divide...
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| Format: | Proceeding Paper |
| Language: | English |
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2009
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| Online Access: | http://irep.iium.edu.my/33493/1/Binder1.pdf |
| _version_ | 1825647664765599744 |
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| author | Al-Ani, Imad Matloub Dally Al-Khafaji , Inaam N. Fakhridin, Mohamed M. Mangalo, Hanna H. Al-Obaidi, Salim Rasheed |
| author_facet | Al-Ani, Imad Matloub Dally Al-Khafaji , Inaam N. Fakhridin, Mohamed M. Mangalo, Hanna H. Al-Obaidi, Salim Rasheed |
| author_sort | Al-Ani, Imad Matloub Dally |
| collection | IIUM |
| description | The aims of this study were to assess the differences in the percentages of abnormal morphology between the epididymal and testicular spermatozoa of mature male offspring mice whose mothers were injected with various doses of lead acetate during gestation. Seventy two healthy female mice were divided into three major groups according to the number of injections involving 1, 2 or 3 injections at 8th day; 8th and 13th days; and 8th, 13th and 18th days of gestation period, respectively. Each major group was subdivided into four minor groups according to of the dosage of lead administration of (0, 25, 50 and 100) mg/Kg. The percentages of abnormal morphology of epididymal and testicular spermatozoa were studied and the data were statistically analyzed. The results of the present study proved that an increased number of injections and/or dose of lead acetate injected to the mothers during gestation cause an elevation in the percentage of abnormal morphology of both epididymal and testicular spermatozoa of the male mice offspring. In conclusion this study demonstrated that lead acetate when exposed prenatally have toxic effects on the sperm abnormal morphology in the offspring male mice most likely by interfering with the phase(s) of spermatogenesis and/or spermiogenesis.
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| first_indexed | 2024-03-05T23:20:57Z |
| format | Proceeding Paper |
| id | oai:generic.eprints.org:33493 |
| institution | International Islamic University Malaysia |
| language | English |
| last_indexed | 2024-03-05T23:20:57Z |
| publishDate | 2009 |
| record_format | dspace |
| spelling | oai:generic.eprints.org:334932013-12-30T01:08:28Z http://irep.iium.edu.my/33493/ The effect of prenatal administration of lead acetate on the morphology of epididymal and testicular spermatozoa in offspring mature male mice Al-Ani, Imad Matloub Dally Al-Khafaji , Inaam N. Fakhridin, Mohamed M. Mangalo, Hanna H. Al-Obaidi, Salim Rasheed QM Human anatomy QP Physiology RB Pathology The aims of this study were to assess the differences in the percentages of abnormal morphology between the epididymal and testicular spermatozoa of mature male offspring mice whose mothers were injected with various doses of lead acetate during gestation. Seventy two healthy female mice were divided into three major groups according to the number of injections involving 1, 2 or 3 injections at 8th day; 8th and 13th days; and 8th, 13th and 18th days of gestation period, respectively. Each major group was subdivided into four minor groups according to of the dosage of lead administration of (0, 25, 50 and 100) mg/Kg. The percentages of abnormal morphology of epididymal and testicular spermatozoa were studied and the data were statistically analyzed. The results of the present study proved that an increased number of injections and/or dose of lead acetate injected to the mothers during gestation cause an elevation in the percentage of abnormal morphology of both epididymal and testicular spermatozoa of the male mice offspring. In conclusion this study demonstrated that lead acetate when exposed prenatally have toxic effects on the sperm abnormal morphology in the offspring male mice most likely by interfering with the phase(s) of spermatogenesis and/or spermiogenesis. 2009 Proceeding Paper PeerReviewed application/pdf en http://irep.iium.edu.my/33493/1/Binder1.pdf Al-Ani, Imad Matloub Dally and Al-Khafaji , Inaam N. and Fakhridin, Mohamed M. and Mangalo, Hanna H. and Al-Obaidi, Salim Rasheed (2009) The effect of prenatal administration of lead acetate on the morphology of epididymal and testicular spermatozoa in offspring mature male mice. In: 21st Veterinary Association Malaysia Congress, 7th-9th August 2009, The Legend, Water Chalets, Port Dickson, Negeri Sembilan. |
| spellingShingle | QM Human anatomy QP Physiology RB Pathology Al-Ani, Imad Matloub Dally Al-Khafaji , Inaam N. Fakhridin, Mohamed M. Mangalo, Hanna H. Al-Obaidi, Salim Rasheed The effect of prenatal administration of lead acetate on the morphology of epididymal and testicular spermatozoa in offspring mature male mice |
| title | The effect of prenatal administration of lead acetate on the morphology of epididymal and testicular spermatozoa in offspring mature male mice |
| title_full | The effect of prenatal administration of lead acetate on the morphology of epididymal and testicular spermatozoa in offspring mature male mice |
| title_fullStr | The effect of prenatal administration of lead acetate on the morphology of epididymal and testicular spermatozoa in offspring mature male mice |
| title_full_unstemmed | The effect of prenatal administration of lead acetate on the morphology of epididymal and testicular spermatozoa in offspring mature male mice |
| title_short | The effect of prenatal administration of lead acetate on the morphology of epididymal and testicular spermatozoa in offspring mature male mice |
| title_sort | effect of prenatal administration of lead acetate on the morphology of epididymal and testicular spermatozoa in offspring mature male mice |
| topic | QM Human anatomy QP Physiology RB Pathology |
| url | http://irep.iium.edu.my/33493/1/Binder1.pdf |
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