Halal issues in the mammalian cell culture for recombinant protein production

Awareness and interest in halal products has significantly increased among muslim and non-muslim countries. Biopharmaceutical products including recombinant therapeutic proteins contribute to a considerable percentage in the worth of the overall global halal industry, which is said to be US$ 2.3 tri...

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Main Author: Arief Ichwan, Solachuddin Jauhari
Format: Proceeding Paper
Language:English
Published: 2013
Subjects:
Online Access:http://irep.iium.edu.my/33811/1/CIA_Biotech_2013.pdf
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author Arief Ichwan, Solachuddin Jauhari
author_facet Arief Ichwan, Solachuddin Jauhari
author_sort Arief Ichwan, Solachuddin Jauhari
collection IIUM
description Awareness and interest in halal products has significantly increased among muslim and non-muslim countries. Biopharmaceutical products including recombinant therapeutic proteins contribute to a considerable percentage in the worth of the overall global halal industry, which is said to be US$ 2.3 trillion. The number and demand for approved biopharmaceutical products produced from mammalian cell culture methods such as vaccines, monoclonal antibodies, antibodies, hormones, and other therapeutic proteins are increasing worldwide. The mammalian cell culture technology has been known to be perfectly suited to the production of recombinant therapeutic proteins. Mammalian cell culture is a general term used for the isolation of the cells of a mammalian from specific tissues further cultured and reproduced in an artificial growth media. The overall process in the recombinant protein synthesis using mammalian cell culture involves the use ingredients or materials that may be questioned from the perspective of halal procedures that make the product cannot fulfill the requirements of halal pharmaceuticals. This review will discuss the application of mammalian cell culture bioprocesses in recombinant biopharmaceutical protein production with focus on the halal-compliance status of the materials and methods.
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spelling oai:generic.eprints.org:338112014-03-19T04:55:42Z http://irep.iium.edu.my/33811/ Halal issues in the mammalian cell culture for recombinant protein production Arief Ichwan, Solachuddin Jauhari T175 Industrial research. Research and development Awareness and interest in halal products has significantly increased among muslim and non-muslim countries. Biopharmaceutical products including recombinant therapeutic proteins contribute to a considerable percentage in the worth of the overall global halal industry, which is said to be US$ 2.3 trillion. The number and demand for approved biopharmaceutical products produced from mammalian cell culture methods such as vaccines, monoclonal antibodies, antibodies, hormones, and other therapeutic proteins are increasing worldwide. The mammalian cell culture technology has been known to be perfectly suited to the production of recombinant therapeutic proteins. Mammalian cell culture is a general term used for the isolation of the cells of a mammalian from specific tissues further cultured and reproduced in an artificial growth media. The overall process in the recombinant protein synthesis using mammalian cell culture involves the use ingredients or materials that may be questioned from the perspective of halal procedures that make the product cannot fulfill the requirements of halal pharmaceuticals. This review will discuss the application of mammalian cell culture bioprocesses in recombinant biopharmaceutical protein production with focus on the halal-compliance status of the materials and methods. 2013 Proceeding Paper PeerReviewed application/pdf en http://irep.iium.edu.my/33811/1/CIA_Biotech_2013.pdf Arief Ichwan, Solachuddin Jauhari (2013) Halal issues in the mammalian cell culture for recombinant protein production. In: National Conference on Industry-Academia Joint Initiatives in Biotechnology 2013, 5 - 7 December 2013, Equatorial Hotel, Cameron Highlands. (Unpublished) http://ciabiotech2013.com
spellingShingle T175 Industrial research. Research and development
Arief Ichwan, Solachuddin Jauhari
Halal issues in the mammalian cell culture for recombinant protein production
title Halal issues in the mammalian cell culture for recombinant protein production
title_full Halal issues in the mammalian cell culture for recombinant protein production
title_fullStr Halal issues in the mammalian cell culture for recombinant protein production
title_full_unstemmed Halal issues in the mammalian cell culture for recombinant protein production
title_short Halal issues in the mammalian cell culture for recombinant protein production
title_sort halal issues in the mammalian cell culture for recombinant protein production
topic T175 Industrial research. Research and development
url http://irep.iium.edu.my/33811/1/CIA_Biotech_2013.pdf
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