Chemical characterization and antioxidant activity of three medicinal Apiaceae species
tCentella asiatica (‘Pegaga’ = Malaysia) is well known plant that has been used as one of the ingredientsin pharmaceutical and cosmetic industries. Using liquid chromatography with diode array and elec-trospray ionization/mass spectrometry (LC–DAD–ESI/MS) analysis, chemical profiling of three differ...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English English |
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Elsevier
2014
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/36383/1/Maulidiani_et_al._2014.pdf http://irep.iium.edu.my/36383/4/36383_Chemical%20characterization%20and%20antioxidant_SCOPUS.pdf |
| _version_ | 1796878736443834368 |
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| author | ., Maulidiani Abas, Faridah Khatib, Alfi Shaari, Khozirah |
| author_facet | ., Maulidiani Abas, Faridah Khatib, Alfi Shaari, Khozirah |
| author_sort | ., Maulidiani |
| collection | IIUM |
| description | tCentella asiatica (‘Pegaga’ = Malaysia) is well known plant that has been used as one of the ingredientsin pharmaceutical and cosmetic industries. Using liquid chromatography with diode array and elec-trospray ionization/mass spectrometry (LC–DAD–ESI/MS) analysis, chemical profiling of three differentPegaga extracts (C. asiatica, H. bonariensis and H. sibthorpioides) revealed variations in their metabo-lite profile. Our findings showed that triterpenes of C. asiatica were characterized by the ursane-typetriterpenes (madecassoside, asiaticoside, madecassic acid, and asiatic acid), while the two Hydrocotylespecies consisted of oleanane-type triterpenes (barrigenol derivatives). Other variations are due tothe difference in phenolic and flavonoid constituents. The three Pegaga extracts were also evalu-ated for their total phenolic content (TPC), 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radicals, andxanthine oxidase inhibition (XOI) activities. The results showed that C. asiatica has the most potentantioxidant activity (TPC = 72.09 mg/100 g DW; DPPH = 72.99 mikrog/ml; XOI = 87.68 mikrog/ml) as compared toH. bonariensis (TPC = 28.55 mg/100 g DW; DPPH = 22.43 mikrog/ml; XOI = 32.23 mikrog/ml) and H. sibthorpioides(TPC = 56.23 mg/100 g DW; DPPH = 37.86 mikrog/ml; XOI = 14.73. mikrog/ml). |
| first_indexed | 2024-03-05T23:25:46Z |
| format | Article |
| id | oai:generic.eprints.org:36383 |
| institution | International Islamic University Malaysia |
| language | English English |
| last_indexed | 2024-03-05T23:25:46Z |
| publishDate | 2014 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | oai:generic.eprints.org:363832017-09-19T08:27:59Z http://irep.iium.edu.my/36383/ Chemical characterization and antioxidant activity of three medicinal Apiaceae species ., Maulidiani Abas, Faridah Khatib, Alfi Shaari, Khozirah QD Chemistry tCentella asiatica (‘Pegaga’ = Malaysia) is well known plant that has been used as one of the ingredientsin pharmaceutical and cosmetic industries. Using liquid chromatography with diode array and elec-trospray ionization/mass spectrometry (LC–DAD–ESI/MS) analysis, chemical profiling of three differentPegaga extracts (C. asiatica, H. bonariensis and H. sibthorpioides) revealed variations in their metabo-lite profile. Our findings showed that triterpenes of C. asiatica were characterized by the ursane-typetriterpenes (madecassoside, asiaticoside, madecassic acid, and asiatic acid), while the two Hydrocotylespecies consisted of oleanane-type triterpenes (barrigenol derivatives). Other variations are due tothe difference in phenolic and flavonoid constituents. The three Pegaga extracts were also evalu-ated for their total phenolic content (TPC), 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radicals, andxanthine oxidase inhibition (XOI) activities. The results showed that C. asiatica has the most potentantioxidant activity (TPC = 72.09 mg/100 g DW; DPPH = 72.99 mikrog/ml; XOI = 87.68 mikrog/ml) as compared toH. bonariensis (TPC = 28.55 mg/100 g DW; DPPH = 22.43 mikrog/ml; XOI = 32.23 mikrog/ml) and H. sibthorpioides(TPC = 56.23 mg/100 g DW; DPPH = 37.86 mikrog/ml; XOI = 14.73. mikrog/ml). Elsevier 2014-03-15 Article PeerReviewed application/pdf en http://irep.iium.edu.my/36383/1/Maulidiani_et_al._2014.pdf application/pdf en http://irep.iium.edu.my/36383/4/36383_Chemical%20characterization%20and%20antioxidant_SCOPUS.pdf ., Maulidiani and Abas, Faridah and Khatib, Alfi and Shaari, Khozirah (2014) Chemical characterization and antioxidant activity of three medicinal Apiaceae species. Industrial Crops and Products, 55. pp. 238-247. ISSN 0926-6690 http://www.sciencedirect.com/science/article/pii/S0926669014000910# 10.1016/j.indcrop.2014.02.013 |
| spellingShingle | QD Chemistry ., Maulidiani Abas, Faridah Khatib, Alfi Shaari, Khozirah Chemical characterization and antioxidant activity of three medicinal Apiaceae species |
| title | Chemical characterization and antioxidant activity of three medicinal Apiaceae species |
| title_full | Chemical characterization and antioxidant activity of three medicinal Apiaceae species |
| title_fullStr | Chemical characterization and antioxidant activity of three medicinal Apiaceae species |
| title_full_unstemmed | Chemical characterization and antioxidant activity of three medicinal Apiaceae species |
| title_short | Chemical characterization and antioxidant activity of three medicinal Apiaceae species |
| title_sort | chemical characterization and antioxidant activity of three medicinal apiaceae species |
| topic | QD Chemistry |
| url | http://irep.iium.edu.my/36383/1/Maulidiani_et_al._2014.pdf http://irep.iium.edu.my/36383/4/36383_Chemical%20characterization%20and%20antioxidant_SCOPUS.pdf |
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