A rare case of acute psychosis as an isolated manifestation of extrapontine myelinolysis
Aims and Background: Central pontine myelinolysis (CPM) and extrapontine myelinolysis (EPM) are recognized as osmotic demyelination syndrome (ODS. ODS is pathologically characterized by non-inflammatory demyelination of several brain structures with sparing of axons. This condition is usually assoc...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SCIENCEDOMAIN international
2014
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/37950/1/20143174480.pdf |
| _version_ | 1796878957568589824 |
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| author | Wan Sulaiman, Wan Aliaa Fan , Kee Hoo Basri, Hamidon Hasan, Shariful Mohd Sazlly Lim, Sazlyna Yoke , Loong Foo Siew , Mooi Ching Ramachandran, Vasudevan Mohamed, Mohd Hazmi Hashim, Hasnur Zaman |
| author_facet | Wan Sulaiman, Wan Aliaa Fan , Kee Hoo Basri, Hamidon Hasan, Shariful Mohd Sazlly Lim, Sazlyna Yoke , Loong Foo Siew , Mooi Ching Ramachandran, Vasudevan Mohamed, Mohd Hazmi Hashim, Hasnur Zaman |
| author_sort | Wan Sulaiman, Wan Aliaa |
| collection | IIUM |
| description | Aims and Background:
Central pontine myelinolysis (CPM) and extrapontine myelinolysis (EPM) are recognized as osmotic demyelination syndrome (ODS. ODS is pathologically characterized by non-inflammatory demyelination of several brain structures with sparing of axons. This condition is usually associated with overzealous correction of hyponatraemia. Acute psychosis as the sole clinical manifestation is extremely rare.
Presentation of Case:
Hence, we report an interesting case of a middle-aged man who was diagnosed with EPM, following rapid correction of hyponatraemia and subsequently developed acute psychosis. He made a good recovery with supportive treatment alone.
Discussion and Conclusion:
The possibility of psychosis as a manifestation of ODS,
particularly in patients with recent correction of hyponatraemia. The rate of correction of plasma sodium level is the key point for preventing ODS and its complications. |
| first_indexed | 2024-03-05T23:28:45Z |
| format | Article |
| id | oai:generic.eprints.org:37950 |
| institution | International Islamic University Malaysia |
| language | English |
| last_indexed | 2024-03-05T23:28:45Z |
| publishDate | 2014 |
| publisher | SCIENCEDOMAIN international |
| record_format | dspace |
| spelling | oai:generic.eprints.org:379502014-11-27T08:49:54Z http://irep.iium.edu.my/37950/ A rare case of acute psychosis as an isolated manifestation of extrapontine myelinolysis Wan Sulaiman, Wan Aliaa Fan , Kee Hoo Basri, Hamidon Hasan, Shariful Mohd Sazlly Lim, Sazlyna Yoke , Loong Foo Siew , Mooi Ching Ramachandran, Vasudevan Mohamed, Mohd Hazmi Hashim, Hasnur Zaman R Medicine (General) RC Internal medicine Aims and Background: Central pontine myelinolysis (CPM) and extrapontine myelinolysis (EPM) are recognized as osmotic demyelination syndrome (ODS. ODS is pathologically characterized by non-inflammatory demyelination of several brain structures with sparing of axons. This condition is usually associated with overzealous correction of hyponatraemia. Acute psychosis as the sole clinical manifestation is extremely rare. Presentation of Case: Hence, we report an interesting case of a middle-aged man who was diagnosed with EPM, following rapid correction of hyponatraemia and subsequently developed acute psychosis. He made a good recovery with supportive treatment alone. Discussion and Conclusion: The possibility of psychosis as a manifestation of ODS, particularly in patients with recent correction of hyponatraemia. The rate of correction of plasma sodium level is the key point for preventing ODS and its complications. SCIENCEDOMAIN international 2014 Article PeerReviewed application/pdf en http://irep.iium.edu.my/37950/1/20143174480.pdf Wan Sulaiman, Wan Aliaa and Fan , Kee Hoo and Basri, Hamidon and Hasan, Shariful and Mohd Sazlly Lim, Sazlyna and Yoke , Loong Foo and Siew , Mooi Ching and Ramachandran, Vasudevan and Mohamed, Mohd Hazmi and Hashim, Hasnur Zaman (2014) A rare case of acute psychosis as an isolated manifestation of extrapontine myelinolysis. British Journal of Medicine & Medical Research, 4 (18). pp. 3555-3560. ISSN 3554 - 3560 http://www.sciencedomain.org/issue.php?iid=480&id=12 10.9734/BJMMR/2014/9615 |
| spellingShingle | R Medicine (General) RC Internal medicine Wan Sulaiman, Wan Aliaa Fan , Kee Hoo Basri, Hamidon Hasan, Shariful Mohd Sazlly Lim, Sazlyna Yoke , Loong Foo Siew , Mooi Ching Ramachandran, Vasudevan Mohamed, Mohd Hazmi Hashim, Hasnur Zaman A rare case of acute psychosis as an isolated manifestation of extrapontine myelinolysis |
| title | A rare case of acute psychosis as an isolated manifestation of extrapontine myelinolysis |
| title_full | A rare case of acute psychosis as an isolated manifestation of extrapontine myelinolysis |
| title_fullStr | A rare case of acute psychosis as an isolated manifestation of extrapontine myelinolysis |
| title_full_unstemmed | A rare case of acute psychosis as an isolated manifestation of extrapontine myelinolysis |
| title_short | A rare case of acute psychosis as an isolated manifestation of extrapontine myelinolysis |
| title_sort | rare case of acute psychosis as an isolated manifestation of extrapontine myelinolysis |
| topic | R Medicine (General) RC Internal medicine |
| url | http://irep.iium.edu.my/37950/1/20143174480.pdf |
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