Recent progress on hydroxyapatite-based dense biomaterials for load bearing bone substitutes
Hydroxyapatite (HA) is the main mineral component of bone tissue, representing ca. 69 vol% in bone and up to 98 vol% in dental enamel. Its chemical composition close to the mineral phase of bone is the origin of its excellent biocompatibility to tissue bone. Hydroxyapatite has been applied in orthop...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Bentham Science
2011
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| Online Access: | http://irep.iium.edu.my/4589/1/MATS-4-1-Sopyan.pdf |
| _version_ | 1796875152105930752 |
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| author | Nawawi, Natasha A Alqap, Asep Sofwan F. Sopyan, Iis |
| author_facet | Nawawi, Natasha A Alqap, Asep Sofwan F. Sopyan, Iis |
| author_sort | Nawawi, Natasha A |
| collection | IIUM |
| description | Hydroxyapatite (HA) is the main mineral component of bone tissue, representing ca. 69 vol% in bone and up to 98 vol% in dental enamel. Its chemical composition close to the mineral phase of bone is the origin of its excellent biocompatibility to tissue bone. Hydroxyapatite has been applied in orthopaedics as block implants, porous, granules and coating material, either dense or porous. However, the application is restricted to non-load bearing application due to its brittleness and low toughness and flexural strength. With this, the development of bioactive dense HA is necessary as it has promising potential in application of load bearing bone implant. Few efforts have been made in developing many methods to produce dense HA. Some of the methods have been combined to prepare dense HA with improved properties.
This paper will be discussing the recent progress on efforts which have been done in improving mechanical properties of hydroxyapatite-based dense type biomaterials for load bearing bone substitutes applications. Some recent patents related to dense calcium phosphate are also reviewed. |
| first_indexed | 2024-03-05T22:34:39Z |
| format | Article |
| id | oai:generic.eprints.org:4589 |
| institution | International Islamic University Malaysia |
| language | English |
| last_indexed | 2024-03-05T22:34:39Z |
| publishDate | 2011 |
| publisher | Bentham Science |
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| spelling | oai:generic.eprints.org:45892011-09-26T03:37:34Z http://irep.iium.edu.my/4589/ Recent progress on hydroxyapatite-based dense biomaterials for load bearing bone substitutes Nawawi, Natasha A Alqap, Asep Sofwan F. Sopyan, Iis T Technology (General) Hydroxyapatite (HA) is the main mineral component of bone tissue, representing ca. 69 vol% in bone and up to 98 vol% in dental enamel. Its chemical composition close to the mineral phase of bone is the origin of its excellent biocompatibility to tissue bone. Hydroxyapatite has been applied in orthopaedics as block implants, porous, granules and coating material, either dense or porous. However, the application is restricted to non-load bearing application due to its brittleness and low toughness and flexural strength. With this, the development of bioactive dense HA is necessary as it has promising potential in application of load bearing bone implant. Few efforts have been made in developing many methods to produce dense HA. Some of the methods have been combined to prepare dense HA with improved properties. This paper will be discussing the recent progress on efforts which have been done in improving mechanical properties of hydroxyapatite-based dense type biomaterials for load bearing bone substitutes applications. Some recent patents related to dense calcium phosphate are also reviewed. Bentham Science 2011 Article PeerReviewed application/pdf en http://irep.iium.edu.my/4589/1/MATS-4-1-Sopyan.pdf Nawawi, Natasha A and Alqap, Asep Sofwan F. and Sopyan, Iis (2011) Recent progress on hydroxyapatite-based dense biomaterials for load bearing bone substitutes. Recent Patents on Materials Science, 4. pp. 63-80. ISSN 1874-4656 http://www.benthamscience.com/mats/ |
| spellingShingle | T Technology (General) Nawawi, Natasha A Alqap, Asep Sofwan F. Sopyan, Iis Recent progress on hydroxyapatite-based dense biomaterials for load bearing bone substitutes |
| title | Recent progress on hydroxyapatite-based dense biomaterials for load bearing bone substitutes
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| title_full | Recent progress on hydroxyapatite-based dense biomaterials for load bearing bone substitutes
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| title_fullStr | Recent progress on hydroxyapatite-based dense biomaterials for load bearing bone substitutes
|
| title_full_unstemmed | Recent progress on hydroxyapatite-based dense biomaterials for load bearing bone substitutes
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| title_short | Recent progress on hydroxyapatite-based dense biomaterials for load bearing bone substitutes
|
| title_sort | recent progress on hydroxyapatite based dense biomaterials for load bearing bone substitutes |
| topic | T Technology (General) |
| url | http://irep.iium.edu.my/4589/1/MATS-4-1-Sopyan.pdf |
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