A hydrophobic barrier deep within the inner pore of the TWIK-1 K2P potassium channel
Recent X-ray crystal structures of the two-pore domain (K2P) family of potassium channels have revealed a unique structural architecture at the point where the cytoplasmic bundle-crossing gate is found in most other tetrameric K+ channels. However, despite the apparently open nature of the inner por...
Main Authors: | Aryal, Prafulla, Abd Wahab, Firdaus, Bucci, Giovanna, Sansom, Mark, Stephen, Tucker |
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Format: | Article |
Language: | English English |
Published: |
Nature Publishing Group
2014
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Subjects: | |
Online Access: | http://irep.iium.edu.my/47584/1/47584.pdf http://irep.iium.edu.my/47584/4/47584_A%20hydrophobic%20barrier%20deep_SCOPUS.pdf |
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