Group-based quantitative structure-activity relationship (G-QSAR) analysis and molecular docking of B-cell lymphoma two (BCL-2) inhibitors

Group-based quantitative structure-activity relationship (G-QSAR) analysis and molecular docking of B-cell lymphoma two (BCL-2) inhibitors

Bcl-2 is the founding protein of Bcl-2 family and it is one of the inner mitochondrial membrane protein which acts as inhibitor of apoptosis, prolong cell survivals and regulate cell death negatively. Bcl-2 has been reported by previous study that it has significant percentage to be presented in man...

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Bibliographic Details
Main Authors: Abdul Samat, Nadia Hanis, Mohamed, Farahidah, Abdullahi , Abubakar
Format: Article
Language:English
Published: Akademi Sains Malaysia and Confederation of Scientific & Technological Association in Malaysia (COSTAM) 2013
Subjects:
QD Chemistry
RM Therapeutics. Pharmacology
RS Pharmacy and materia medica
Online Access:http://irep.iium.edu.my/49054/4/49054.pdf

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