Non Hodgkin lymphoma presenting with adrenal insufficiency and bilateral huge adrenal masses
Adrenal involvement secondary to lymphoma is not commonly seen. We report a case of a 62-year old lady, with underlying hypertension on treatment, but otherwise healthy, presented with adrenal insufficiency with large bilateral adrenal masses, complicated with exudative left pleural effusion. Sh...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Malaysian Endocrine and Metabolic Society
2014
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/49068/1/PP-042.pdf |
| _version_ | 1825649485980631040 |
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| author | Huai, Heng Loh Sukor, Norlela AW, Norasyikin M, Norlaila O, Mohd Rahman R, Subashini Shahar, Mohammad Arif Omar, Ahmad Marzuki WS, Wan Juani D, Azura Ooi, CP K, Nor Azmi |
| author_facet | Huai, Heng Loh Sukor, Norlela AW, Norasyikin M, Norlaila O, Mohd Rahman R, Subashini Shahar, Mohammad Arif Omar, Ahmad Marzuki WS, Wan Juani D, Azura Ooi, CP K, Nor Azmi |
| author_sort | Huai, Heng Loh |
| collection | IIUM |
| description | Adrenal involvement secondary to lymphoma is not commonly seen.
We report a case of a 62-year old lady, with underlying hypertension on
treatment, but otherwise healthy, presented with adrenal insufficiency
with large bilateral adrenal masses, complicated with exudative left
pleural effusion. She responded to intravenous hydrocortisone of 50mg
tds. Computed tomography (CT) showed large heterogenous bilateral
suprarenal masses (Figure 1, Figure 2). There were areas of necrosis with
no calcification within the mass. Multiple lymphadenopathy in the abdominal
region and mediastinum were noted. Lactate dehydrogenase level was
elevated. Fungal and tuberculous cultures were negative. Trucut biopsy
of the lesion showed Diffuse Large B cell Lymphoma. She was started
on chemotherapy (Rituximab-CHOP). Secondary involvement of bilateral
adrenal glands due to widespread lymphoma is not common, with Diffuse
Large B cell Lymphoma being the most frequently seen. This is to highlight
lymphoma as a possible cause of patient presenting with large bilateral
adrenal masses and adrenal insufficiency. |
| first_indexed | 2024-03-05T23:48:16Z |
| format | Article |
| id | oai:generic.eprints.org:49068 |
| institution | International Islamic University Malaysia |
| language | English |
| last_indexed | 2024-03-05T23:48:16Z |
| publishDate | 2014 |
| publisher | Malaysian Endocrine and Metabolic Society |
| record_format | dspace |
| spelling | oai:generic.eprints.org:490682018-06-12T03:32:25Z http://irep.iium.edu.my/49068/ Non Hodgkin lymphoma presenting with adrenal insufficiency and bilateral huge adrenal masses Huai, Heng Loh Sukor, Norlela AW, Norasyikin M, Norlaila O, Mohd Rahman R, Subashini Shahar, Mohammad Arif Omar, Ahmad Marzuki WS, Wan Juani D, Azura Ooi, CP K, Nor Azmi RC Internal medicine Adrenal involvement secondary to lymphoma is not commonly seen. We report a case of a 62-year old lady, with underlying hypertension on treatment, but otherwise healthy, presented with adrenal insufficiency with large bilateral adrenal masses, complicated with exudative left pleural effusion. She responded to intravenous hydrocortisone of 50mg tds. Computed tomography (CT) showed large heterogenous bilateral suprarenal masses (Figure 1, Figure 2). There were areas of necrosis with no calcification within the mass. Multiple lymphadenopathy in the abdominal region and mediastinum were noted. Lactate dehydrogenase level was elevated. Fungal and tuberculous cultures were negative. Trucut biopsy of the lesion showed Diffuse Large B cell Lymphoma. She was started on chemotherapy (Rituximab-CHOP). Secondary involvement of bilateral adrenal glands due to widespread lymphoma is not common, with Diffuse Large B cell Lymphoma being the most frequently seen. This is to highlight lymphoma as a possible cause of patient presenting with large bilateral adrenal masses and adrenal insufficiency. Malaysian Endocrine and Metabolic Society 2014-05 Article PeerReviewed application/pdf en http://irep.iium.edu.my/49068/1/PP-042.pdf Huai, Heng Loh and Sukor, Norlela and AW, Norasyikin and M, Norlaila and O, Mohd Rahman and R, Subashini and Shahar, Mohammad Arif and Omar, Ahmad Marzuki and WS, Wan Juani and D, Azura and Ooi, CP and K, Nor Azmi (2014) Non Hodgkin lymphoma presenting with adrenal insufficiency and bilateral huge adrenal masses. Journal of Endocrinology and Metabolism, 4 (1(Sup)). p. 29. ISSN 2229-9572 http://www.jmems.org/index.php/jmems/issue/view/5 |
| spellingShingle | RC Internal medicine Huai, Heng Loh Sukor, Norlela AW, Norasyikin M, Norlaila O, Mohd Rahman R, Subashini Shahar, Mohammad Arif Omar, Ahmad Marzuki WS, Wan Juani D, Azura Ooi, CP K, Nor Azmi Non Hodgkin lymphoma presenting with adrenal insufficiency and bilateral huge adrenal masses |
| title | Non Hodgkin lymphoma presenting with adrenal
insufficiency and bilateral huge adrenal masses |
| title_full | Non Hodgkin lymphoma presenting with adrenal
insufficiency and bilateral huge adrenal masses |
| title_fullStr | Non Hodgkin lymphoma presenting with adrenal
insufficiency and bilateral huge adrenal masses |
| title_full_unstemmed | Non Hodgkin lymphoma presenting with adrenal
insufficiency and bilateral huge adrenal masses |
| title_short | Non Hodgkin lymphoma presenting with adrenal
insufficiency and bilateral huge adrenal masses |
| title_sort | non hodgkin lymphoma presenting with adrenal insufficiency and bilateral huge adrenal masses |
| topic | RC Internal medicine |
| url | http://irep.iium.edu.my/49068/1/PP-042.pdf |
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