Hyaluronidase inhibitory activity of Pentacylic triterpenoids from Prismatomeris tetrandra (Roxb.) K. Schum: Isolation, synthesis and QSAR study
The mammalian hyaluronidase degrades hyaluronic acid by the cleavage of the β-1,4-glycosidic bond furnishing a tetrasaccharide molecule as the main product which is a highly angiogenic and potent inducer of inflammatory cytokines. Ursolic acid 1, isolated from Prismatomeris tetrandra, was identified...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI
2016
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/49229/1/ijms-17-00143.pdf |