Improvement of production of citric acid from oil palm empty fruit bunches: Optimization of media by statistical experimental designs
A sequential optimization based on statistical design and one-factor-at-a-time (OFAT) method was employed to optimize the media constituents for the improvement of citric acid production from oil palm empty fruit bunches (EFB) through solid state bioconversion using Aspergillus niger IBO-103MNB. The...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier Science
2009
|
| Subjects: | |
| Online Access: | http://irep.iium.edu.my/5059/1/Citric-acid-media-original-publisher.pdf |
| _version_ | 1825644624852549632 |
|---|---|
| author | Bari, Md. Niamul Alam, Md. Zahangir Muyibi, Suleyman Aremu Jamal, Parveen Al-Mamun, Abdullah |
| author_facet | Bari, Md. Niamul Alam, Md. Zahangir Muyibi, Suleyman Aremu Jamal, Parveen Al-Mamun, Abdullah |
| author_sort | Bari, Md. Niamul |
| collection | IIUM |
| description | A sequential optimization based on statistical design and one-factor-at-a-time (OFAT) method was employed to optimize the media constituents for the improvement of citric acid production from oil palm empty fruit bunches (EFB) through solid state bioconversion using Aspergillus niger IBO-103MNB. The results obtained from the Plackett–Burman design indicated that the co-substrate (sucrose), stimulator
(methanol) and minerals (Zn, Cu, Mn and Mg) were found to be the major factors for further optimization. Based on the OFAT method, the selected medium constituents and inoculum concentration were optimized by the central composite design (CCD) under the response surface methodology (RSM). The statistical analysis showed that the optimum media containing 6.4% (w/w) of sucrose, 9% (v/w) of minerals and
15.5% (v/w) of inoculum gave the maximum production of citric acid (337.94 g/kg of dry EFB). The analysis
showed that sucrose (p < 0.0011) and mineral solution (p < 0.0061) were more significant compared
to inoculum concentration (p < 0.0127) for the citric acid production. |
| first_indexed | 2024-03-05T22:35:32Z |
| format | Article |
| id | oai:generic.eprints.org:5059 |
| institution | International Islamic University Malaysia |
| language | English |
| last_indexed | 2024-03-05T22:35:32Z |
| publishDate | 2009 |
| publisher | Elsevier Science |
| record_format | dspace |
| spelling | oai:generic.eprints.org:50592021-02-11T03:57:52Z http://irep.iium.edu.my/5059/ Improvement of production of citric acid from oil palm empty fruit bunches: Optimization of media by statistical experimental designs Bari, Md. Niamul Alam, Md. Zahangir Muyibi, Suleyman Aremu Jamal, Parveen Al-Mamun, Abdullah TP Chemical technology TP248.13 Biotechnology A sequential optimization based on statistical design and one-factor-at-a-time (OFAT) method was employed to optimize the media constituents for the improvement of citric acid production from oil palm empty fruit bunches (EFB) through solid state bioconversion using Aspergillus niger IBO-103MNB. The results obtained from the Plackett–Burman design indicated that the co-substrate (sucrose), stimulator (methanol) and minerals (Zn, Cu, Mn and Mg) were found to be the major factors for further optimization. Based on the OFAT method, the selected medium constituents and inoculum concentration were optimized by the central composite design (CCD) under the response surface methodology (RSM). The statistical analysis showed that the optimum media containing 6.4% (w/w) of sucrose, 9% (v/w) of minerals and 15.5% (v/w) of inoculum gave the maximum production of citric acid (337.94 g/kg of dry EFB). The analysis showed that sucrose (p < 0.0011) and mineral solution (p < 0.0061) were more significant compared to inoculum concentration (p < 0.0127) for the citric acid production. Elsevier Science 2009 Article PeerReviewed application/pdf en http://irep.iium.edu.my/5059/1/Citric-acid-media-original-publisher.pdf Bari, Md. Niamul and Alam, Md. Zahangir and Muyibi, Suleyman Aremu and Jamal, Parveen and Al-Mamun, Abdullah (2009) Improvement of production of citric acid from oil palm empty fruit bunches: Optimization of media by statistical experimental designs. Bioresource Technology, 100 (12). pp. 3113-3120. ISSN 09608524 http://dx.doi.org/10.1016/j.biortech.2009.01.005 doi:10.1016/j.biortech.2009.01.005 |
| spellingShingle | TP Chemical technology TP248.13 Biotechnology Bari, Md. Niamul Alam, Md. Zahangir Muyibi, Suleyman Aremu Jamal, Parveen Al-Mamun, Abdullah Improvement of production of citric acid from oil palm empty fruit bunches: Optimization of media by statistical experimental designs |
| title | Improvement of production of citric acid from oil palm empty fruit bunches: Optimization of media by statistical experimental designs |
| title_full | Improvement of production of citric acid from oil palm empty fruit bunches: Optimization of media by statistical experimental designs |
| title_fullStr | Improvement of production of citric acid from oil palm empty fruit bunches: Optimization of media by statistical experimental designs |
| title_full_unstemmed | Improvement of production of citric acid from oil palm empty fruit bunches: Optimization of media by statistical experimental designs |
| title_short | Improvement of production of citric acid from oil palm empty fruit bunches: Optimization of media by statistical experimental designs |
| title_sort | improvement of production of citric acid from oil palm empty fruit bunches optimization of media by statistical experimental designs |
| topic | TP Chemical technology TP248.13 Biotechnology |
| url | http://irep.iium.edu.my/5059/1/Citric-acid-media-original-publisher.pdf |
| work_keys_str_mv | AT barimdniamul improvementofproductionofcitricacidfromoilpalmemptyfruitbunchesoptimizationofmediabystatisticalexperimentaldesigns AT alammdzahangir improvementofproductionofcitricacidfromoilpalmemptyfruitbunchesoptimizationofmediabystatisticalexperimentaldesigns AT muyibisuleymanaremu improvementofproductionofcitricacidfromoilpalmemptyfruitbunchesoptimizationofmediabystatisticalexperimentaldesigns AT jamalparveen improvementofproductionofcitricacidfromoilpalmemptyfruitbunchesoptimizationofmediabystatisticalexperimentaldesigns AT almamunabdullah improvementofproductionofcitricacidfromoilpalmemptyfruitbunchesoptimizationofmediabystatisticalexperimentaldesigns |