Clinacanthus nutans: a review of the medicinal uses, pharmacology and phytochemistry

Clinacanthus nutans Lindau is known as snake grass belonging to the Acanthaceae family. This plant has diverse and potential medicinal uses in traditional herbal medicine for treating skin rashes, insects and snake bites, lesions caused by herpes simplex virus, diabetes, and gout in Malaysia, Indone...

Full description

Bibliographic Details
Main Authors: Alam, Md Ariful, Ferdosh, Sahena, Ghafoor, Kashif, Hakim, Md Abdul, Juraimi, Abdul Shukor, Khatib, Alfi, Sarker, Md. Zaidul Islam
Format: Article
Language:English
English
Published: Elsevier (Singapore) Pte Ltd 2016
Subjects:
Online Access:http://irep.iium.edu.my/51511/1/1-s2.0-S1995764516300116-main.pdf
http://irep.iium.edu.my/51511/4/51511_Clinacanthus_nutans-_a_review_of_the_medicinal_WOS_and_SCOPUS.pdf
_version_ 1825649794956132352
author Alam, Md Ariful
Ferdosh, Sahena
Ghafoor, Kashif
Hakim, Md Abdul
Juraimi, Abdul Shukor
Khatib, Alfi
Sarker, Md. Zaidul Islam
author_facet Alam, Md Ariful
Ferdosh, Sahena
Ghafoor, Kashif
Hakim, Md Abdul
Juraimi, Abdul Shukor
Khatib, Alfi
Sarker, Md. Zaidul Islam
author_sort Alam, Md Ariful
collection IIUM
description Clinacanthus nutans Lindau is known as snake grass belonging to the Acanthaceae family. This plant has diverse and potential medicinal uses in traditional herbal medicine for treating skin rashes, insects and snake bites, lesions caused by herpes simplex virus, diabetes, and gout in Malaysia, Indonesia, Thailand and China. Phytochemical investigations documented the varied contents of bioactive compounds from this plant namely flavonoids, glycosides, glycoglycerolipids, cerebrosides and monoacylmonogalatosylglycerol. The pharmacological experiment proved that various types of extracts and pure compounds from this species exhibited a broad range of biological properties such as anti-inflammatory, antiviral, antioxidant, and anti-diabetic activities. The findings of toxicity study showed that extracts from this plant did not show any toxicity thus it can be used as strong therapeutic agents for specific diseased conditions. However, further experiments on chemical components and their mode of action showing biological activities are required to elucidate the complete phytochemical profile and assess to confirm their suitability for future drugs. This review summarizes the medicinal uses, phytochemistry and pharmacology of this plant in order to explore its therapeutic potential and gaps necessitating for prospected research work.
first_indexed 2024-03-05T23:52:51Z
format Article
id oai:generic.eprints.org:51511
institution International Islamic University Malaysia
language English
English
last_indexed 2024-03-05T23:52:51Z
publishDate 2016
publisher Elsevier (Singapore) Pte Ltd
record_format dspace
spelling oai:generic.eprints.org:515112017-04-05T03:33:45Z http://irep.iium.edu.my/51511/ Clinacanthus nutans: a review of the medicinal uses, pharmacology and phytochemistry Alam, Md Ariful Ferdosh, Sahena Ghafoor, Kashif Hakim, Md Abdul Juraimi, Abdul Shukor Khatib, Alfi Sarker, Md. Zaidul Islam Q Science (General) RS Pharmacy and materia medica Clinacanthus nutans Lindau is known as snake grass belonging to the Acanthaceae family. This plant has diverse and potential medicinal uses in traditional herbal medicine for treating skin rashes, insects and snake bites, lesions caused by herpes simplex virus, diabetes, and gout in Malaysia, Indonesia, Thailand and China. Phytochemical investigations documented the varied contents of bioactive compounds from this plant namely flavonoids, glycosides, glycoglycerolipids, cerebrosides and monoacylmonogalatosylglycerol. The pharmacological experiment proved that various types of extracts and pure compounds from this species exhibited a broad range of biological properties such as anti-inflammatory, antiviral, antioxidant, and anti-diabetic activities. The findings of toxicity study showed that extracts from this plant did not show any toxicity thus it can be used as strong therapeutic agents for specific diseased conditions. However, further experiments on chemical components and their mode of action showing biological activities are required to elucidate the complete phytochemical profile and assess to confirm their suitability for future drugs. This review summarizes the medicinal uses, phytochemistry and pharmacology of this plant in order to explore its therapeutic potential and gaps necessitating for prospected research work. Elsevier (Singapore) Pte Ltd 2016-04 Article PeerReviewed application/pdf en http://irep.iium.edu.my/51511/1/1-s2.0-S1995764516300116-main.pdf application/pdf en http://irep.iium.edu.my/51511/4/51511_Clinacanthus_nutans-_a_review_of_the_medicinal_WOS_and_SCOPUS.pdf Alam, Md Ariful and Ferdosh, Sahena and Ghafoor, Kashif and Hakim, Md Abdul and Juraimi, Abdul Shukor and Khatib, Alfi and Sarker, Md. Zaidul Islam (2016) Clinacanthus nutans: a review of the medicinal uses, pharmacology and phytochemistry. Asian Pacific Journal of Tropical Medicine, 9 (4). pp. 402-409. ISSN 1995-7645 http://www.sciencedirect.com/science/article/pii/S1995764516300116 10.1016/j.apjtm.2016.03.011
spellingShingle Q Science (General)
RS Pharmacy and materia medica
Alam, Md Ariful
Ferdosh, Sahena
Ghafoor, Kashif
Hakim, Md Abdul
Juraimi, Abdul Shukor
Khatib, Alfi
Sarker, Md. Zaidul Islam
Clinacanthus nutans: a review of the medicinal uses, pharmacology and phytochemistry
title Clinacanthus nutans: a review of the medicinal uses, pharmacology and phytochemistry
title_full Clinacanthus nutans: a review of the medicinal uses, pharmacology and phytochemistry
title_fullStr Clinacanthus nutans: a review of the medicinal uses, pharmacology and phytochemistry
title_full_unstemmed Clinacanthus nutans: a review of the medicinal uses, pharmacology and phytochemistry
title_short Clinacanthus nutans: a review of the medicinal uses, pharmacology and phytochemistry
title_sort clinacanthus nutans a review of the medicinal uses pharmacology and phytochemistry
topic Q Science (General)
RS Pharmacy and materia medica
url http://irep.iium.edu.my/51511/1/1-s2.0-S1995764516300116-main.pdf
http://irep.iium.edu.my/51511/4/51511_Clinacanthus_nutans-_a_review_of_the_medicinal_WOS_and_SCOPUS.pdf
work_keys_str_mv AT alammdariful clinacanthusnutansareviewofthemedicinalusespharmacologyandphytochemistry
AT ferdoshsahena clinacanthusnutansareviewofthemedicinalusespharmacologyandphytochemistry
AT ghafoorkashif clinacanthusnutansareviewofthemedicinalusespharmacologyandphytochemistry
AT hakimmdabdul clinacanthusnutansareviewofthemedicinalusespharmacologyandphytochemistry
AT juraimiabdulshukor clinacanthusnutansareviewofthemedicinalusespharmacologyandphytochemistry
AT khatibalfi clinacanthusnutansareviewofthemedicinalusespharmacologyandphytochemistry
AT sarkermdzaidulislam clinacanthusnutansareviewofthemedicinalusespharmacologyandphytochemistry