| Summary: | Periodontitis is an infectious disease in the supporting tissues of teeth
caused by microorganisms causing progressive damage to the periodontal
ligament and alveolar bone, if not done proper care can lead to tooth loss.
Periodontitis treatment is to eliminate the periodontal pathogens with scaling root
planing (SRP), which eliminates the hard and soft deposits and bacteria attached
to the tooth surface and the subgingival, thus eliminating the bacteria. Cleaning of
periodontal pathogens and their products with the SRP is sometimes not optimal
because there are parts that can not be accessed by means of SRP, thus giving
local or systemic antimicrobials is recommended to improve the therapeutic
outcome SRP. Ciprofloxacin is a second generation derivative fluroquinolon,
active with a broad range of gram-negative and gram-positive facultative
periodontal pathogens. This study aims to determine the effectiveness of the
treatment difference between scaling root planing (SRP) without and with the
provision of oral ciprofloxacin in patients with periodontitis measured by the type
of leucocyte count parameters consist of neutrophils, basophils, eosinofi,
lymphocytes and monocytes in gingival crevicular fluid.
The study was conducted on 20 cases of chronic periodontitis pocket depth
> 5 mm, the subjects were divided into two groups of 10 patients with
periodontitis were scaling root planing (SRP) without ciprofloxacin and 10
patients with periodontitis with ciprofloxacin per oral administration. Capture and
measurement of leukocyte counts consisting of neutrophils, eosinophils,
basophils, monocytes and lymphocytes gingival crevicular fluid before SRP and 8
days after SRP.
Statistical analysis of non parametric Mann Whitney test showed no
significant differences (p> 0.05) on leucocyte counts of neutrophils, lymphocytes
and eosinophils. The number of neutrophils in the SRP without and with
ciprofloxacin showed an increase, the number of lymphocytes and eosinophils in
the SRP with and without ciprofloxacin has decreased, number of basophils and
monocytes 0 (zero) so it can not be calculated statistically. The conclusion this
study shows the results of treatment of scaling root planing (SRP) without oral
ciprofloxacin is as effective as SRP with the provision of oral ciprofloxacin in
patients with periodontitis measured by the type of leucocyte count parameters ie
the number of neutrophils, lymphocytes and eosonofil in gingival crevicular fluid.
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