| Summary: | Recently, an increasingly high prevalence of genetic diseases, including
Thalassemia Beta. Increasingly better healthcare services result in the
enhancement of the life expectancy of patients with Thalassemia Beta.
Consequently, it increases the demand for cosmetic treatments, especially
orthodontic treatment of the patients. There is only a few data of the facial skeletal
profile of the patients with Thalassemia Beta in Indonesia. The aims of this study
is to investigate the facial skeletal profile of the patients with Thalassemia Beta
by examining maxillo-mandibular relationship, maxillary and cranial base
relationship and the position of mandible on the cranial base of the patients using
cephalometry analysis with Ramos and Martinelli method.
Thirteen patients with Thalassemia Beta who meet the inclusion criteria
and have routinely visited the pediatric health installation of Dr. Sardjito hospital
are included in the study. They consist of 5 males and 8 females of 12-23 years of
age. Subsequently, they undergo a lateral cephalography and the results are
analyzed in a cephalometry analysis using Ramos and Martinelli method. The
results of the analysis are statistically analyzed using one sample t- test.
The results of the study show that there is a significant difference (p<0.05)
between the normal values of SNB, ANB and convexity angles, and Wits�
appraisal of male group and differential unit measurement. There is not any
significant difference (p>0.05) between the SNA angle and the Wits� appraisal of
female group. Facial angle is classified into normal lower limit.
The facial skeletal profile of the patients with Thalassemia Beta is more
convex than normal, while the maxillo-mandibular relationship is skeletal class
II. The maxilla and cranial base relationship is normal, and the mandible position
on the cranial base is retrognation.
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