Pengaruh Koinduksi Anestesi Ketamin 0,4 mg/kgBB terhadap Hipotensi pada Induksi Anestesi dengan Propofol 2mg/kgBB

Induction anesthesia requirement for General Anesthesia. One of the drug option in induction is propofol, because in addition to the rapid onset also causes relaxation of airway muscles. However, propofol also caused a hipotension, especially if given quickly (15 seconds). So that require medication...

Full description

Bibliographic Details
Main Authors: , dr. Joko Purnomo, , dr. Pandit Sarosa, Sp.An-K
Format: Thesis
Published: [Yogyakarta] : Universitas Gadjah Mada 2011
Subjects:
ETD
_version_ 1826043666467127296
author , dr. Joko Purnomo
, dr. Pandit Sarosa, Sp.An-K
author_facet , dr. Joko Purnomo
, dr. Pandit Sarosa, Sp.An-K
author_sort , dr. Joko Purnomo
collection UGM
description Induction anesthesia requirement for General Anesthesia. One of the drug option in induction is propofol, because in addition to the rapid onset also causes relaxation of airway muscles. However, propofol also caused a hipotension, especially if given quickly (15 seconds). So that require medication coinduction to prevent these hemodynamic impairment. Ketamine is a drug that has sympathomimetic effects which can inhibit the vasodilation of propofol. The aim of this study is to test the hypothesis that coinduction with ketamine 0.4 mg / kg create a more stable hemodynamic on propofol 2mg/kg induction than without coinduction. A prospective randomized double blind study will be perfomed in 114 healthy patients (ASA I or II) undergoing general anesthesia. Patients were randomly allocated into two groups to recieve coinduction with ketamin 0.4mg/kg as group K with subject of 57 patients and saline as group P with subject of 57 patients.Haemodynamic change afther induction will be compare between the groups. The data analysis by t-test, and p<0,05 considered significantly different.
first_indexed 2024-03-13T22:07:24Z
format Thesis
id oai:generic.eprints.org:89474
institution Universiti Gadjah Mada
last_indexed 2024-03-13T22:07:24Z
publishDate 2011
publisher [Yogyakarta] : Universitas Gadjah Mada
record_format dspace
spelling oai:generic.eprints.org:894742014-08-20T02:54:36Z https://repository.ugm.ac.id/89474/ Pengaruh Koinduksi Anestesi Ketamin 0,4 mg/kgBB terhadap Hipotensi pada Induksi Anestesi dengan Propofol 2mg/kgBB , dr. Joko Purnomo , dr. Pandit Sarosa, Sp.An-K ETD Induction anesthesia requirement for General Anesthesia. One of the drug option in induction is propofol, because in addition to the rapid onset also causes relaxation of airway muscles. However, propofol also caused a hipotension, especially if given quickly (15 seconds). So that require medication coinduction to prevent these hemodynamic impairment. Ketamine is a drug that has sympathomimetic effects which can inhibit the vasodilation of propofol. The aim of this study is to test the hypothesis that coinduction with ketamine 0.4 mg / kg create a more stable hemodynamic on propofol 2mg/kg induction than without coinduction. A prospective randomized double blind study will be perfomed in 114 healthy patients (ASA I or II) undergoing general anesthesia. Patients were randomly allocated into two groups to recieve coinduction with ketamin 0.4mg/kg as group K with subject of 57 patients and saline as group P with subject of 57 patients.Haemodynamic change afther induction will be compare between the groups. The data analysis by t-test, and p<0,05 considered significantly different. [Yogyakarta] : Universitas Gadjah Mada 2011 Thesis NonPeerReviewed , dr. Joko Purnomo and , dr. Pandit Sarosa, Sp.An-K (2011) Pengaruh Koinduksi Anestesi Ketamin 0,4 mg/kgBB terhadap Hipotensi pada Induksi Anestesi dengan Propofol 2mg/kgBB. UNSPECIFIED thesis, UNSPECIFIED. http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=51985
spellingShingle ETD
, dr. Joko Purnomo
, dr. Pandit Sarosa, Sp.An-K
Pengaruh Koinduksi Anestesi Ketamin 0,4 mg/kgBB terhadap Hipotensi pada Induksi Anestesi dengan Propofol 2mg/kgBB
title Pengaruh Koinduksi Anestesi Ketamin 0,4 mg/kgBB terhadap Hipotensi pada Induksi Anestesi dengan Propofol 2mg/kgBB
title_full Pengaruh Koinduksi Anestesi Ketamin 0,4 mg/kgBB terhadap Hipotensi pada Induksi Anestesi dengan Propofol 2mg/kgBB
title_fullStr Pengaruh Koinduksi Anestesi Ketamin 0,4 mg/kgBB terhadap Hipotensi pada Induksi Anestesi dengan Propofol 2mg/kgBB
title_full_unstemmed Pengaruh Koinduksi Anestesi Ketamin 0,4 mg/kgBB terhadap Hipotensi pada Induksi Anestesi dengan Propofol 2mg/kgBB
title_short Pengaruh Koinduksi Anestesi Ketamin 0,4 mg/kgBB terhadap Hipotensi pada Induksi Anestesi dengan Propofol 2mg/kgBB
title_sort pengaruh koinduksi anestesi ketamin 0 4 mg kgbb terhadap hipotensi pada induksi anestesi dengan propofol 2mg kgbb
topic ETD
work_keys_str_mv AT drjokopurnomo pengaruhkoinduksianestesiketamin04mgkgbbterhadaphipotensipadainduksianestesidenganpropofol2mgkgbb
AT drpanditsarosaspank pengaruhkoinduksianestesiketamin04mgkgbbterhadaphipotensipadainduksianestesidenganpropofol2mgkgbb