Pengaruh Koinduksi Anestesi Ketamin 0,4 mg/kgBB terhadap Hipotensi pada Induksi Anestesi dengan Propofol 2mg/kgBB
Induction anesthesia requirement for General Anesthesia. One of the drug option in induction is propofol, because in addition to the rapid onset also causes relaxation of airway muscles. However, propofol also caused a hipotension, especially if given quickly (15 seconds). So that require medication...
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Format: | Thesis |
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[Yogyakarta] : Universitas Gadjah Mada
2011
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author | , dr. Joko Purnomo , dr. Pandit Sarosa, Sp.An-K |
author_facet | , dr. Joko Purnomo , dr. Pandit Sarosa, Sp.An-K |
author_sort | , dr. Joko Purnomo |
collection | UGM |
description | Induction anesthesia requirement for General Anesthesia. One of the drug
option in induction is propofol, because in addition to the rapid onset also causes
relaxation of airway muscles. However, propofol also caused a hipotension,
especially if given quickly (15 seconds). So that require medication coinduction to
prevent these hemodynamic impairment. Ketamine is a drug that has
sympathomimetic effects which can inhibit the vasodilation of propofol. The aim
of this study is to test the hypothesis that coinduction with ketamine 0.4 mg / kg
create a more stable hemodynamic on propofol 2mg/kg induction than without
coinduction.
A prospective randomized double blind study will be perfomed in 114
healthy patients (ASA I or II) undergoing general anesthesia. Patients were
randomly allocated into two groups to recieve coinduction with ketamin 0.4mg/kg
as group K with subject of 57 patients and saline as group P with subject of 57
patients.Haemodynamic change afther induction will be compare between the
groups. The data analysis by t-test, and p<0,05 considered significantly different. |
first_indexed | 2024-03-13T22:07:24Z |
format | Thesis |
id | oai:generic.eprints.org:89474 |
institution | Universiti Gadjah Mada |
last_indexed | 2024-03-13T22:07:24Z |
publishDate | 2011 |
publisher | [Yogyakarta] : Universitas Gadjah Mada |
record_format | dspace |
spelling | oai:generic.eprints.org:894742014-08-20T02:54:36Z https://repository.ugm.ac.id/89474/ Pengaruh Koinduksi Anestesi Ketamin 0,4 mg/kgBB terhadap Hipotensi pada Induksi Anestesi dengan Propofol 2mg/kgBB , dr. Joko Purnomo , dr. Pandit Sarosa, Sp.An-K ETD Induction anesthesia requirement for General Anesthesia. One of the drug option in induction is propofol, because in addition to the rapid onset also causes relaxation of airway muscles. However, propofol also caused a hipotension, especially if given quickly (15 seconds). So that require medication coinduction to prevent these hemodynamic impairment. Ketamine is a drug that has sympathomimetic effects which can inhibit the vasodilation of propofol. The aim of this study is to test the hypothesis that coinduction with ketamine 0.4 mg / kg create a more stable hemodynamic on propofol 2mg/kg induction than without coinduction. A prospective randomized double blind study will be perfomed in 114 healthy patients (ASA I or II) undergoing general anesthesia. Patients were randomly allocated into two groups to recieve coinduction with ketamin 0.4mg/kg as group K with subject of 57 patients and saline as group P with subject of 57 patients.Haemodynamic change afther induction will be compare between the groups. The data analysis by t-test, and p<0,05 considered significantly different. [Yogyakarta] : Universitas Gadjah Mada 2011 Thesis NonPeerReviewed , dr. Joko Purnomo and , dr. Pandit Sarosa, Sp.An-K (2011) Pengaruh Koinduksi Anestesi Ketamin 0,4 mg/kgBB terhadap Hipotensi pada Induksi Anestesi dengan Propofol 2mg/kgBB. UNSPECIFIED thesis, UNSPECIFIED. http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=51985 |
spellingShingle | ETD , dr. Joko Purnomo , dr. Pandit Sarosa, Sp.An-K Pengaruh Koinduksi Anestesi Ketamin 0,4 mg/kgBB terhadap Hipotensi pada Induksi Anestesi dengan Propofol 2mg/kgBB |
title | Pengaruh Koinduksi Anestesi Ketamin 0,4 mg/kgBB terhadap Hipotensi
pada Induksi Anestesi dengan Propofol 2mg/kgBB |
title_full | Pengaruh Koinduksi Anestesi Ketamin 0,4 mg/kgBB terhadap Hipotensi
pada Induksi Anestesi dengan Propofol 2mg/kgBB |
title_fullStr | Pengaruh Koinduksi Anestesi Ketamin 0,4 mg/kgBB terhadap Hipotensi
pada Induksi Anestesi dengan Propofol 2mg/kgBB |
title_full_unstemmed | Pengaruh Koinduksi Anestesi Ketamin 0,4 mg/kgBB terhadap Hipotensi
pada Induksi Anestesi dengan Propofol 2mg/kgBB |
title_short | Pengaruh Koinduksi Anestesi Ketamin 0,4 mg/kgBB terhadap Hipotensi
pada Induksi Anestesi dengan Propofol 2mg/kgBB |
title_sort | pengaruh koinduksi anestesi ketamin 0 4 mg kgbb terhadap hipotensi pada induksi anestesi dengan propofol 2mg kgbb |
topic | ETD |
work_keys_str_mv | AT drjokopurnomo pengaruhkoinduksianestesiketamin04mgkgbbterhadaphipotensipadainduksianestesidenganpropofol2mgkgbb AT drpanditsarosaspank pengaruhkoinduksianestesiketamin04mgkgbbterhadaphipotensipadainduksianestesidenganpropofol2mgkgbb |