PENGARUH PEMBERIAN CAMPURAN MADU, JINTAN HITAM, PROPOLIS DAN ROYAL JELI TERHADAP SEL �-PANKREAS DAN KADAR MALONDIALDEHID PADA TIKUS WISTAR PASCA PAPARAN STREPTOZOTOCI

Research Background: Hyperglycemic chronic could cause free radical. Free radical caused an increasing of oxidative stress, reducing the antioxidant, and an increasing of peroxidative lipid, and the damage of β pancreas cell. The final product of peroxidative lipid was malondialdehid (MDA). The dam...

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Bibliographic Details
Main Authors: , Drs. H. Sunyoto, B.Sc, Apt., , dr. Setyo Purwono.,M.Kes.,Sp.PD
Format: Thesis
Published: [Yogyakarta] : Universitas Gadjah Mada 2011
Subjects:
ETD
Description
Summary:Research Background: Hyperglycemic chronic could cause free radical. Free radical caused an increasing of oxidative stress, reducing the antioxidant, and an increasing of peroxidative lipid, and the damage of β pancreas cell. The final product of peroxidative lipid was malondialdehid (MDA). The damage of β pancreas cell decreased the insulin production so that it caused hyperglycemia chronic. The anti-oxidant activities of honey, black dill, propolis, and prodigal broodinging were expected to reduce free radical, so that they could reduce the MDA level and the amount of β pancreas cell vacuole. Research Objectives: to indicate the influence of the mixture of 40% honey, 30% dill, 20% propolis, and 10% prodigal broodinging to the MDA level and the amount of β pancreas cell vacuole. Research Method: Thirty white male Wistar hyperglycemic rat intraperitonially inducted with STZ (Group 2 � 6) and six normal rats. Groups 4, 5, and 6 were treated with the mixture of honey, black dill, propolis, and prodigal broodinging with the dosage 0,6