| Summary: | S Introduction : pinal anesthesia is increasingly popular in use, however, there are
any problems include onset and duration that can vary in accordance with local
anesthesi used. In addition to using local anesthesi, sometimes adjuvant to increase
the duration and quality of intraoperative analgesia. In addition to using opioid as
adjuvants, can also be used non-opioid drug among others with acethylcoline esterase
inhibotors
Method : Study design with Randomized Controlled Trial. Population were patients
who were scheduled for elective surgery under regional anesthesia with Subarachnoid
Block (SAB) in the Center of Surgery Building of Dr. Sardjito Hospital Yogyakarta.
This research consisted of sixty patient divided into two groups each consisting of 30
patients. Group F received hyperbaric Bupivacaine 0,5% 12,5 mg with adjuvant
Fentanyl 12,5 g and Group B received hyperbaric Bupivacaine 0,5% 12,5 mg with
adjuvant Neostigmin 50 The results g. were assessed about comparison between
onset and duration of both groups
was no statistically different Result : There between two group in the onset of
sensoric and motoric (p>0,05). The mean of sensoric onset from Fentanyl group was
9,50±2,813minutes compared with Neostigmin group 9,80±1,699minutes. In
addition, motoric onset of group F was 6,50±2,502 compared to group N which was
5,93±1,780minutes. The duration of sensoric block was defined as the regression to
S2 (F=153,67±12,313 vs N=216,67±16,844minutes), showed statistically significant
differece. While the duration of motoric block also statistically significant
(F=145,33±14,499 vs N=203±15,570minutes)
similar with onset
Conclusion : SAB with Bupivacaine 0,5% 12,5mg hyperbaric and adjuvant
Neostigmin 50µg provide longer duration compared to Bupivacaine 0,5% 12,5mg
hyperbaric with Fentanyl 12,5µg, between two group
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