| Summary: | Diarrhea is the cause of morbidity and mortality in children. Probiotics can
decrease the diarrhea frequency and shorten the duration of diarrhea. There are two
kind of probiotics, lived and tyndallized probiotics. Tyndallized probiotic is
sterilizated probiotic which can not produce the active metabolit but still can make
effect in human imunity. The aim of this study is to evaluate the effectiveness of
tyndallized probiotic on WHO standard therapy in children with acute watery
diarrhea.
Design of this study was prospective experimental research, with single blind
method in children age between 3-60 months which diagnosed as acute watery
diarrhea at RSU Gunungsitoli Nias, Sumatera Utara. Taking sample with simple
randomized method and parents interviews..
From 100 acute watery diarrhea cases which fulfill the inclusion and
exclusion criteria, devided into 2 groups : 50 cases with WHO standard therapy for
acute watery diarrhea only dan 50 cases added tyndallyzed probuotics in WHO
standard therapy. There is no significant difference between basic characteristics in
this two groups. Diarrhea duration for group which added tyndallized probiotics was
4,6 ± 2,3 days and 3,95 ± 1,3 days on group with WHO standard therapy only (p >
0,05). Diarrhea frequency in the fifth days for group which added tyndallized
probiotics was 1,56 ± 0,67 and on group with WHO standard therapy only was 1,90
± 0,99 (p > 0,05). There is no significant differences between added tyndallyzed
probiotics on WHO standard therapy and using WHO standard therapy only to
decrease duration and frequency of diarrhea
|
|---|