| Summary: | Pneumonia is one of the infectious disease which often occurs in children
under five years old. At the time of infection, pro-inflammatory cytokines would be
released. It is tought that these pro-inflammatory cytokines causes changes in iron
homeostasis in the body. The objective of this study is to know the correlation
between CRP levels and serum iron levels in children with severe pneumonia.
An analytic cross sectional study was done on children aged 6 months-5 years
old with severe pneumonia at Sanglah Hospital Denpasar from April 2010-September
2010. The laboratoric examination includes testing the CRP levels and serum iron
levels. The correlation between CRP levels and serum iron levels are calculated using
a computer software.
From 69 children with severe pneumonia, 23 children fulfilled the inclusion
and exclusion criteria. In children with severe pneumonia, the average CRP level was
9,22 mg/L and serum iron level was 25,55 ug/dL. The coefficient correlation between
CRP level and serum iron level was -0,580 with p = 0,004. The determination
coefficient value is 31,6 %, which means the 31,6% decrease in serum iron is
influenced by the increase in CRP. In children with severe pneumonia, the CRP
levels correlates negatively with the serum iron levels.
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