| Summary: | Shivering is an unpleasant and frequent complication and it�s seen in 57% case after
spinal anesthesia. Numerous pharmacological interventions have been proposed, but their relative efficacy remains unclear. The efficacy of pethidin in prevention shivering after spinal anesthesia has been studied. The aim of this study is to compare effectivity of ketamine 0,25 mg/kgBW + midazolam 37µg/kgBW intravenous and pethidin 0,5 mg/kBW intravenous for prevention shivering after spinal anesthesia.
This is a randomized double blind controlled study. Subjects are 94 male and female,
ages 18-60 years old, physical status ASA I-II, who will undergo elective surgery in Dr. Sardjito General Hospital, Yogyakarta. The sample will be divided randomly into two groups. Group A will received pethidin 0,5 mg/kgBW iv and group B will received ketamine 0,25 mg/kgBW iv + midazolam 37 µg/kgBW iv to prevent shivering after spinal anesthesia. Sensory block level, blood pressure, incidence and intensity of shivering data will be collected, and the adverse effects of drugs will be recorded along spinal anesthesia. All data will be analysed by using Tindependent
and Chi-square test.
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