PENUAAN FIBROBLAS KELOID OLEH TRIAMSINOLON ASETONIDA ATAU MITOMISIN C
The defective induction of senescence may provoke keloid. Therapy that induces fibroblasts senescence can be used to prevent the keloid. Triamcinolon acetonide (TA) or Mitomycin C (MMC) can improve keloid by decreasing fibroblasts proliferation that is also the characteristic of cellular senescence....
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| Format: | Thesis |
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[Yogyakarta] : Universitas Gadjah Mada
2011
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| _version_ | 1826043815773863936 |
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| author | , dr. Marta Dwi Rifka , dr. Y. Widodo Wirohadidjojo, Sp.KK(K) |
| author_facet | , dr. Marta Dwi Rifka , dr. Y. Widodo Wirohadidjojo, Sp.KK(K) |
| author_sort | , dr. Marta Dwi Rifka |
| collection | UGM |
| description | The defective induction of senescence may provoke keloid. Therapy that
induces fibroblasts senescence can be used to prevent the keloid. Triamcinolon
acetonide (TA) or Mitomycin C (MMC) can improve keloid by decreasing
fibroblasts proliferation that is also the characteristic of cellular senescence.
We investigated the effect of TA or MMC on SA-βgal senescence-marker
expression of keloid fibroblasts, the optimum dose of TA or MMC and the
potential difference in increasing the expression between the use of TA and
MMC.
Passage III keloid fibroblasts culture was divided into 8 groups of
treatment: placebo, 150 µM H2O2 (as procedure control), TA (10, 20, 40 µM), and
MMC (0,015 |
| first_indexed | 2024-03-13T22:09:43Z |
| format | Thesis |
| id | oai:generic.eprints.org:90218 |
| institution | Universiti Gadjah Mada |
| last_indexed | 2024-03-13T22:09:43Z |
| publishDate | 2011 |
| publisher | [Yogyakarta] : Universitas Gadjah Mada |
| record_format | dspace |
| spelling | oai:generic.eprints.org:902182014-08-20T02:54:36Z https://repository.ugm.ac.id/90218/ PENUAAN FIBROBLAS KELOID OLEH TRIAMSINOLON ASETONIDA ATAU MITOMISIN C , dr. Marta Dwi Rifka , dr. Y. Widodo Wirohadidjojo, Sp.KK(K) ETD The defective induction of senescence may provoke keloid. Therapy that induces fibroblasts senescence can be used to prevent the keloid. Triamcinolon acetonide (TA) or Mitomycin C (MMC) can improve keloid by decreasing fibroblasts proliferation that is also the characteristic of cellular senescence. We investigated the effect of TA or MMC on SA-βgal senescence-marker expression of keloid fibroblasts, the optimum dose of TA or MMC and the potential difference in increasing the expression between the use of TA and MMC. Passage III keloid fibroblasts culture was divided into 8 groups of treatment: placebo, 150 µM H2O2 (as procedure control), TA (10, 20, 40 µM), and MMC (0,015 [Yogyakarta] : Universitas Gadjah Mada 2011 Thesis NonPeerReviewed , dr. Marta Dwi Rifka and , dr. Y. Widodo Wirohadidjojo, Sp.KK(K) (2011) PENUAAN FIBROBLAS KELOID OLEH TRIAMSINOLON ASETONIDA ATAU MITOMISIN C. UNSPECIFIED thesis, UNSPECIFIED. http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=51186 |
| spellingShingle | ETD , dr. Marta Dwi Rifka , dr. Y. Widodo Wirohadidjojo, Sp.KK(K) PENUAAN FIBROBLAS KELOID OLEH TRIAMSINOLON ASETONIDA ATAU MITOMISIN C |
| title | PENUAAN FIBROBLAS KELOID OLEH
TRIAMSINOLON ASETONIDA ATAU MITOMISIN C |
| title_full | PENUAAN FIBROBLAS KELOID OLEH
TRIAMSINOLON ASETONIDA ATAU MITOMISIN C |
| title_fullStr | PENUAAN FIBROBLAS KELOID OLEH
TRIAMSINOLON ASETONIDA ATAU MITOMISIN C |
| title_full_unstemmed | PENUAAN FIBROBLAS KELOID OLEH
TRIAMSINOLON ASETONIDA ATAU MITOMISIN C |
| title_short | PENUAAN FIBROBLAS KELOID OLEH
TRIAMSINOLON ASETONIDA ATAU MITOMISIN C |
| title_sort | penuaan fibroblas keloid oleh triamsinolon asetonida atau mitomisin c |
| topic | ETD |
| work_keys_str_mv | AT drmartadwirifka penuaanfibroblaskeloidolehtriamsinolonasetonidaataumitomisinc AT drywidodowirohadidjojospkkk penuaanfibroblaskeloidolehtriamsinolonasetonidaataumitomisinc |