UK-2A ANALOGUES: POTENTIAL INHIBITORS OF BCL-XL
<p>UK-2A is a novel antifungi from Streptomyces sp. 517-02, and its structure is similar to that of Antimycin A3. Antimycin A3 itself was found to induce apoptosis by inhibition of Bcl-xL, an anti-apoptotic enzyme in mitochondria.<br /> In our research, several open-chained analogues of...
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[Yogyakarta] : Fak. MIPA Universitas Gadjah Mada
2007
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