| Summary: | Background: Obesity in adolescents has become health problem. Central obesity
is associated with insulin resistance. Theoretically, insulin resistance will cause
impaired glucose tolerance (IGT), and it could develop into type 2 diabetes.
The aims of this study are to evaluate the difference in IGT prevalence in central
and non central obesity and to identify the risk factors associated with IGT.
Methods: We conducted a cross sectional study at 3 private secondary schools in
Yogyakarta, and recruited 62 obese female students aged 12-18 years. We
classified the subjects into central obesity (BMI > +2SD and waist circumference
> p90) and non central obesity based on anthropometric. Fasting glucose and 2
hours after loading were measured in all subjects. Differences in proportions
between the two groups was calculated using chi-square test and risk factors
associated with IGT were calculated using multivariate logistic regression with
95% confidence interval.
Results: Out of 62 subjects, 14 subjects revealed IGT and central obesity showed
significantly higher prevalence compared to non central obesity (11/31 vs 3/31 , P
= 0.03). We also found that central obesity is the only risk factor of IGT (OR =
4.6
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