| Summary: | Psoriasis is a chronic inflammatory disease, characterized by erythematous
plaques covered with silvery white scale, lesions can be localized or generalized.
Psoriasis vulgaris can be provoked or exacerbated by infection and microorganism
colonization in the skin and mucous membrane that can lead to disease aggravation.
There was positive correlation between Candida sp colonization and disease severity,
therefore correlation between Candida sp colonization density and disease severity is not yet understood. The objective of the study was to determine the correlation between Candida sp colonization density and disease severity among psoriasis vulgaris patient. A crosssectional study were done among psoriasis vulgaris patient visiting outpatient Department of Dermatology and Venereology Clinic Dr Sardjito Hospital. The samples were collected by swab from perianal skin of the subject and cultured on Saboraoud agar medium. Candida sp colonies were identified by macroscopic assessment and count by manual system. Ordinal logistic regression test was used to analyze the data. They were eighty subjects consist of 43(53.8%) males and 37(46.3%) female, with a mean of age 45.01 ± 14.50 years and mean of PASI score 14.79 ± 12.92 were enrolled in the study. Of those eighty cultured samples observes as low growth density 57(71.25%), moderate growth 18(22.5%), and strong growth 5(6.25%) consecutively. Statistical analysis proved that no significant correlation between Candida sp colonization density and disease severity. Probability study indicate that the relative risk to suffer from severe psoriasis among its colonization growth rate were 54%, 62%, and 46% for low growth, moderate growth, and strong growth respectively. The study proved that the Candida sp colonization density in the perianal region of psoriasis vulgaris patients does not influence disease severity
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