PERBANDINGAN KEEFEKTIFAN DAN KEAMANAN INDUKSI PERSALINAN MENGGUNAKAN MISOPROSTOL SUBLINGUAL 25 μg ANTARA INTERVAL 4 JAM DAN 6 JAM
Background: Misoprostol is widely used to induce labor. Different ways of administration provides difference result and side effects. Sublingual administration gives misoprostol acid peak blood levels faster than the other way, but gradually decrease after 2 hours and it is minimally detected after...
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| Format: | Thesis |
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[Yogyakarta] : Universitas Gadjah Mada
2012
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| author | , Erick Yuane , dr. H. Risanto Siswosudarmo, Sp.OG(K) |
| author_facet | , Erick Yuane , dr. H. Risanto Siswosudarmo, Sp.OG(K) |
| author_sort | , Erick Yuane |
| collection | UGM |
| description | Background: Misoprostol is widely used to induce labor. Different ways of
administration provides difference result and side effects. Sublingual
administration gives misoprostol acid peak blood levels faster than the
other way, but gradually decrease after 2 hours and it is minimally
detected after 4 hours.
Objective: To compare efficacy and safety of misoprostol 25 μg given
sublingually at intervals of 4 and 6 hours for the induction of labor.
Design: Non-blind randomized controlled trial.
Material and method: The study was conducted in three hospitals
(Sardjito hospital Yogyakarta, Muntilan hospital, Banjarnegara hospital),
and Mergangsan health center Yogyakarta from March to December 2010.
Subjects were pregnant women with an indication of induction of labor
who meet inclusion and exclusion criteria. Randomization is done by a
computer generated random number. The treated group received 25 μg
sublingual misoprostol at 4 hours intervals and control group at 6 hours
intervals. The results of the study is the success of induction, duration in
arriving to second stage since the last drug administration, and side
effects. Chi square and t-test was used for statistical analysis.
Results: 150 subjects consisted of 75 treated and 75 control met the
study criteria. The success rate was 78.7% in the treated group vs. 72% in
the controlled group (RR 1.09 |
| first_indexed | 2024-03-13T22:38:15Z |
| format | Thesis |
| id | oai:generic.eprints.org:99143 |
| institution | Universiti Gadjah Mada |
| last_indexed | 2024-03-13T22:38:15Z |
| publishDate | 2012 |
| publisher | [Yogyakarta] : Universitas Gadjah Mada |
| record_format | dspace |
| spelling | oai:generic.eprints.org:991432016-03-04T08:46:33Z https://repository.ugm.ac.id/99143/ PERBANDINGAN KEEFEKTIFAN DAN KEAMANAN INDUKSI PERSALINAN MENGGUNAKAN MISOPROSTOL SUBLINGUAL 25 μg ANTARA INTERVAL 4 JAM DAN 6 JAM , Erick Yuane , dr. H. Risanto Siswosudarmo, Sp.OG(K) ETD Background: Misoprostol is widely used to induce labor. Different ways of administration provides difference result and side effects. Sublingual administration gives misoprostol acid peak blood levels faster than the other way, but gradually decrease after 2 hours and it is minimally detected after 4 hours. Objective: To compare efficacy and safety of misoprostol 25 μg given sublingually at intervals of 4 and 6 hours for the induction of labor. Design: Non-blind randomized controlled trial. Material and method: The study was conducted in three hospitals (Sardjito hospital Yogyakarta, Muntilan hospital, Banjarnegara hospital), and Mergangsan health center Yogyakarta from March to December 2010. Subjects were pregnant women with an indication of induction of labor who meet inclusion and exclusion criteria. Randomization is done by a computer generated random number. The treated group received 25 μg sublingual misoprostol at 4 hours intervals and control group at 6 hours intervals. The results of the study is the success of induction, duration in arriving to second stage since the last drug administration, and side effects. Chi square and t-test was used for statistical analysis. Results: 150 subjects consisted of 75 treated and 75 control met the study criteria. The success rate was 78.7% in the treated group vs. 72% in the controlled group (RR 1.09 [Yogyakarta] : Universitas Gadjah Mada 2012 Thesis NonPeerReviewed , Erick Yuane and , dr. H. Risanto Siswosudarmo, Sp.OG(K) (2012) PERBANDINGAN KEEFEKTIFAN DAN KEAMANAN INDUKSI PERSALINAN MENGGUNAKAN MISOPROSTOL SUBLINGUAL 25 μg ANTARA INTERVAL 4 JAM DAN 6 JAM. UNSPECIFIED thesis, UNSPECIFIED. http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=54871 |
| spellingShingle | ETD , Erick Yuane , dr. H. Risanto Siswosudarmo, Sp.OG(K) PERBANDINGAN KEEFEKTIFAN DAN KEAMANAN INDUKSI PERSALINAN MENGGUNAKAN MISOPROSTOL SUBLINGUAL 25 μg ANTARA INTERVAL 4 JAM DAN 6 JAM |
| title | PERBANDINGAN KEEFEKTIFAN DAN KEAMANAN
INDUKSI PERSALINAN MENGGUNAKAN
MISOPROSTOL SUBLINGUAL 25 μg
ANTARA INTERVAL 4 JAM DAN 6 JAM |
| title_full | PERBANDINGAN KEEFEKTIFAN DAN KEAMANAN
INDUKSI PERSALINAN MENGGUNAKAN
MISOPROSTOL SUBLINGUAL 25 μg
ANTARA INTERVAL 4 JAM DAN 6 JAM |
| title_fullStr | PERBANDINGAN KEEFEKTIFAN DAN KEAMANAN
INDUKSI PERSALINAN MENGGUNAKAN
MISOPROSTOL SUBLINGUAL 25 μg
ANTARA INTERVAL 4 JAM DAN 6 JAM |
| title_full_unstemmed | PERBANDINGAN KEEFEKTIFAN DAN KEAMANAN
INDUKSI PERSALINAN MENGGUNAKAN
MISOPROSTOL SUBLINGUAL 25 μg
ANTARA INTERVAL 4 JAM DAN 6 JAM |
| title_short | PERBANDINGAN KEEFEKTIFAN DAN KEAMANAN
INDUKSI PERSALINAN MENGGUNAKAN
MISOPROSTOL SUBLINGUAL 25 μg
ANTARA INTERVAL 4 JAM DAN 6 JAM |
| title_sort | perbandingan keefektifan dan keamanan induksi persalinan menggunakan misoprostol sublingual 25 i 1 4g antara interval 4 jam dan 6 jam |
| topic | ETD |
| work_keys_str_mv | AT erickyuane perbandingankeefektifandankeamananinduksipersalinanmenggunakanmisoprostolsublingual25i1⁄4gantarainterval4jamdan6jam AT drhrisantosiswosudarmospogk perbandingankeefektifandankeamananinduksipersalinanmenggunakanmisoprostolsublingual25i1⁄4gantarainterval4jamdan6jam |