PEMODELAN SISTEMINTERAKSI OBAT DENGANMENGGUNAKAN FUZZY INFERENCE SYSTEM DAN PARETO OPTIMALITY

Drug interactions is the interaction occurs between drugs that consumption simultaneously. Drug interactions can produce a good effect on patients, but not rarely produce adverse effects. Patients with diabetes and hypertension expected to control blood pressure and blood glucose levels to remain in...

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Main Authors: , Elena Yustina, S.T., , Prof. Drs. Subanar, Ph.D
Format: Thesis
Published: [Yogyakarta] : Universitas Gadjah Mada 2012
Subjects:
ETD
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author , Elena Yustina, S.T.
, Prof. Drs. Subanar, Ph.D
author_facet , Elena Yustina, S.T.
, Prof. Drs. Subanar, Ph.D
author_sort , Elena Yustina, S.T.
collection UGM
description Drug interactions is the interaction occurs between drugs that consumption simultaneously. Drug interactions can produce a good effect on patients, but not rarely produce adverse effects. Patients with diabetes and hypertension expected to control blood pressure and blood glucose levels to remain in normal circumstances, it is necessary to consider the use of medications for both diseases in order to produce effective therapies. Pareto optimality is a popular concept in the determination optimal solution of multiobjective problems. In determining the optimal solution of multiobjective problem should pay attention for each objective function, frequently conflicting objective functions. The interaction of two drugs has two objective function that is maximizing the positive effects and minimize negative effects. So its use is necessary to find optimal solutions to achieve the expected therapeutic. This research using Fuzzy Inference Sistem (FIS) to determine the appropriate medication to keep blood pressure and blood glucose levels of patients with hypertension and diabetes under control in normal and Pareto optimality to determine drug optimal solution. Fuzzy Inference System generates output choice of drug classes based on fuzzy rules in accordance with the patient's disease condition. Pareto optimality produces a pair solution for diabetes and hypertension drug that satisfy thresholds the Minimum Effective Concentration (MEC) and Maximum Toxic Concentration (MTC) of each drug.
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spelling oai:generic.eprints.org:994302016-03-04T08:46:29Z https://repository.ugm.ac.id/99430/ PEMODELAN SISTEMINTERAKSI OBAT DENGANMENGGUNAKAN FUZZY INFERENCE SYSTEM DAN PARETO OPTIMALITY , Elena Yustina, S.T. , Prof. Drs. Subanar, Ph.D ETD Drug interactions is the interaction occurs between drugs that consumption simultaneously. Drug interactions can produce a good effect on patients, but not rarely produce adverse effects. Patients with diabetes and hypertension expected to control blood pressure and blood glucose levels to remain in normal circumstances, it is necessary to consider the use of medications for both diseases in order to produce effective therapies. Pareto optimality is a popular concept in the determination optimal solution of multiobjective problems. In determining the optimal solution of multiobjective problem should pay attention for each objective function, frequently conflicting objective functions. The interaction of two drugs has two objective function that is maximizing the positive effects and minimize negative effects. So its use is necessary to find optimal solutions to achieve the expected therapeutic. This research using Fuzzy Inference Sistem (FIS) to determine the appropriate medication to keep blood pressure and blood glucose levels of patients with hypertension and diabetes under control in normal and Pareto optimality to determine drug optimal solution. Fuzzy Inference System generates output choice of drug classes based on fuzzy rules in accordance with the patient's disease condition. Pareto optimality produces a pair solution for diabetes and hypertension drug that satisfy thresholds the Minimum Effective Concentration (MEC) and Maximum Toxic Concentration (MTC) of each drug. [Yogyakarta] : Universitas Gadjah Mada 2012 Thesis NonPeerReviewed , Elena Yustina, S.T. and , Prof. Drs. Subanar, Ph.D (2012) PEMODELAN SISTEMINTERAKSI OBAT DENGANMENGGUNAKAN FUZZY INFERENCE SYSTEM DAN PARETO OPTIMALITY. UNSPECIFIED thesis, UNSPECIFIED. http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=55680
spellingShingle ETD
, Elena Yustina, S.T.
, Prof. Drs. Subanar, Ph.D
PEMODELAN SISTEMINTERAKSI OBAT DENGANMENGGUNAKAN FUZZY INFERENCE SYSTEM DAN PARETO OPTIMALITY
title PEMODELAN SISTEMINTERAKSI OBAT DENGANMENGGUNAKAN FUZZY INFERENCE SYSTEM DAN PARETO OPTIMALITY
title_full PEMODELAN SISTEMINTERAKSI OBAT DENGANMENGGUNAKAN FUZZY INFERENCE SYSTEM DAN PARETO OPTIMALITY
title_fullStr PEMODELAN SISTEMINTERAKSI OBAT DENGANMENGGUNAKAN FUZZY INFERENCE SYSTEM DAN PARETO OPTIMALITY
title_full_unstemmed PEMODELAN SISTEMINTERAKSI OBAT DENGANMENGGUNAKAN FUZZY INFERENCE SYSTEM DAN PARETO OPTIMALITY
title_short PEMODELAN SISTEMINTERAKSI OBAT DENGANMENGGUNAKAN FUZZY INFERENCE SYSTEM DAN PARETO OPTIMALITY
title_sort pemodelan sisteminteraksi obat denganmenggunakan fuzzy inference system dan pareto optimality
topic ETD
work_keys_str_mv AT elenayustinast pemodelansisteminteraksiobatdenganmenggunakanfuzzyinferencesystemdanparetooptimality
AT profdrssubanarphd pemodelansisteminteraksiobatdenganmenggunakanfuzzyinferencesystemdanparetooptimality