PERBANDINGAN PERUBAHAN HEMODINAMIK PASCAINTUBASI OROTRAKEA PADA PEMBERIAN LIDOKAIN 2% 5 cc INSTILASI OROFARINGEAL DENGAN LIDOKAIN 2% 1,5 mg/kgbb INTRAVENA

Background. Orotracheal intubation can cause increasing in hemodynamic responses which can increase morbidity and mortality. This study tested the hypothesis that oropharyngeal lidocaine instillation is better in decrease hemodynamic changes post orotracheal intubation compare with intravenous lidoc...

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Main Authors: , Asep Indah Wuddi Arief, , dr. Pandit Sarosa, Sp.An-K
Format: Thesis
Published: [Yogyakarta] : Universitas Gadjah Mada 2012
Subjects:
ETD
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author , Asep Indah Wuddi Arief
, dr. Pandit Sarosa, Sp.An-K
author_facet , Asep Indah Wuddi Arief
, dr. Pandit Sarosa, Sp.An-K
author_sort , Asep Indah Wuddi Arief
collection UGM
description Background. Orotracheal intubation can cause increasing in hemodynamic responses which can increase morbidity and mortality. This study tested the hypothesis that oropharyngeal lidocaine instillation is better in decrease hemodynamic changes post orotracheal intubation compare with intravenous lidocaine. Methods. A prospective, randomized double blind controlled trial study was performed in 101 patient (ASA I-II) undergoing general anesthesia with orotracheal intubation. Patient were randomly allocated into one of two groups to receive oropharyngeal lidocaine 2% 5 cc (group IO, n = 51) and intravenous lidocaine 2% 1,5 mg/bodyweight (Group IV, n = 50) 3 minute before orotracheal intubation. The incidence of increasing MAP, SBP, DBP, and HR > 20% was compared between the two groups. Results. The incidence of increasing MAP > 20% in IO group (29%) was significantly lower than IV group (56%) (p = 0,007), RR 0,52, CI 95% 0,32-0,85). The incidence of increasing SBP, DBP, and HR > 20% in IO group (27%, 29%, 9,8%) was significantly lower than IV group respectively (60%, 64%, 38%) (p = 0,007, p = 0,000, p = 0,001). Hemodynamic increase occur at 1 minute post orotracheal intubation and will return to basal at 3-10 minute post orotracheal intubation. Conclusion. Adminitration oropharyngeal lidocaine 2% 5 cc instillation was better in decreasing hemodynamic changes post orotracheal intubation compared with intravenous lidocaine 2% 1,5 mg/bodyweight.
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spelling oai:generic.eprints.org:995742016-03-04T08:45:44Z https://repository.ugm.ac.id/99574/ PERBANDINGAN PERUBAHAN HEMODINAMIK PASCAINTUBASI OROTRAKEA PADA PEMBERIAN LIDOKAIN 2% 5 cc INSTILASI OROFARINGEAL DENGAN LIDOKAIN 2% 1,5 mg/kgbb INTRAVENA , Asep Indah Wuddi Arief , dr. Pandit Sarosa, Sp.An-K ETD Background. Orotracheal intubation can cause increasing in hemodynamic responses which can increase morbidity and mortality. This study tested the hypothesis that oropharyngeal lidocaine instillation is better in decrease hemodynamic changes post orotracheal intubation compare with intravenous lidocaine. Methods. A prospective, randomized double blind controlled trial study was performed in 101 patient (ASA I-II) undergoing general anesthesia with orotracheal intubation. Patient were randomly allocated into one of two groups to receive oropharyngeal lidocaine 2% 5 cc (group IO, n = 51) and intravenous lidocaine 2% 1,5 mg/bodyweight (Group IV, n = 50) 3 minute before orotracheal intubation. The incidence of increasing MAP, SBP, DBP, and HR > 20% was compared between the two groups. Results. The incidence of increasing MAP > 20% in IO group (29%) was significantly lower than IV group (56%) (p = 0,007), RR 0,52, CI 95% 0,32-0,85). The incidence of increasing SBP, DBP, and HR > 20% in IO group (27%, 29%, 9,8%) was significantly lower than IV group respectively (60%, 64%, 38%) (p = 0,007, p = 0,000, p = 0,001). Hemodynamic increase occur at 1 minute post orotracheal intubation and will return to basal at 3-10 minute post orotracheal intubation. Conclusion. Adminitration oropharyngeal lidocaine 2% 5 cc instillation was better in decreasing hemodynamic changes post orotracheal intubation compared with intravenous lidocaine 2% 1,5 mg/bodyweight. [Yogyakarta] : Universitas Gadjah Mada 2012 Thesis NonPeerReviewed , Asep Indah Wuddi Arief and , dr. Pandit Sarosa, Sp.An-K (2012) PERBANDINGAN PERUBAHAN HEMODINAMIK PASCAINTUBASI OROTRAKEA PADA PEMBERIAN LIDOKAIN 2% 5 cc INSTILASI OROFARINGEAL DENGAN LIDOKAIN 2% 1,5 mg/kgbb INTRAVENA. UNSPECIFIED thesis, UNSPECIFIED. http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=56012
spellingShingle ETD
, Asep Indah Wuddi Arief
, dr. Pandit Sarosa, Sp.An-K
PERBANDINGAN PERUBAHAN HEMODINAMIK PASCAINTUBASI OROTRAKEA PADA PEMBERIAN LIDOKAIN 2% 5 cc INSTILASI OROFARINGEAL DENGAN LIDOKAIN 2% 1,5 mg/kgbb INTRAVENA
title PERBANDINGAN PERUBAHAN HEMODINAMIK PASCAINTUBASI OROTRAKEA PADA PEMBERIAN LIDOKAIN 2% 5 cc INSTILASI OROFARINGEAL DENGAN LIDOKAIN 2% 1,5 mg/kgbb INTRAVENA
title_full PERBANDINGAN PERUBAHAN HEMODINAMIK PASCAINTUBASI OROTRAKEA PADA PEMBERIAN LIDOKAIN 2% 5 cc INSTILASI OROFARINGEAL DENGAN LIDOKAIN 2% 1,5 mg/kgbb INTRAVENA
title_fullStr PERBANDINGAN PERUBAHAN HEMODINAMIK PASCAINTUBASI OROTRAKEA PADA PEMBERIAN LIDOKAIN 2% 5 cc INSTILASI OROFARINGEAL DENGAN LIDOKAIN 2% 1,5 mg/kgbb INTRAVENA
title_full_unstemmed PERBANDINGAN PERUBAHAN HEMODINAMIK PASCAINTUBASI OROTRAKEA PADA PEMBERIAN LIDOKAIN 2% 5 cc INSTILASI OROFARINGEAL DENGAN LIDOKAIN 2% 1,5 mg/kgbb INTRAVENA
title_short PERBANDINGAN PERUBAHAN HEMODINAMIK PASCAINTUBASI OROTRAKEA PADA PEMBERIAN LIDOKAIN 2% 5 cc INSTILASI OROFARINGEAL DENGAN LIDOKAIN 2% 1,5 mg/kgbb INTRAVENA
title_sort perbandingan perubahan hemodinamik pascaintubasi orotrakea pada pemberian lidokain 2 5 cc instilasi orofaringeal dengan lidokain 2 1 5 mg kgbb intravena
topic ETD
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