PERBANDINGAN PERUBAHAN HEMODINAMIK PASCAINTUBASI OROTRAKEA PADA PEMBERIAN LIDOKAIN 2% 5 cc INSTILASI OROFARINGEAL DENGAN LIDOKAIN 2% 1,5 mg/kgbb INTRAVENA
Background. Orotracheal intubation can cause increasing in hemodynamic responses which can increase morbidity and mortality. This study tested the hypothesis that oropharyngeal lidocaine instillation is better in decrease hemodynamic changes post orotracheal intubation compare with intravenous lidoc...
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Format: | Thesis |
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[Yogyakarta] : Universitas Gadjah Mada
2012
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author | , Asep Indah Wuddi Arief , dr. Pandit Sarosa, Sp.An-K |
author_facet | , Asep Indah Wuddi Arief , dr. Pandit Sarosa, Sp.An-K |
author_sort | , Asep Indah Wuddi Arief |
collection | UGM |
description | Background. Orotracheal intubation can cause increasing in hemodynamic responses which can increase morbidity and mortality. This study tested the hypothesis that oropharyngeal lidocaine instillation is better in decrease hemodynamic changes post orotracheal intubation compare with intravenous lidocaine.
Methods. A prospective, randomized double blind controlled trial study was performed in 101 patient (ASA I-II) undergoing general anesthesia with orotracheal intubation. Patient were randomly allocated into one of two groups to receive oropharyngeal lidocaine 2% 5 cc (group IO, n = 51) and intravenous lidocaine 2% 1,5 mg/bodyweight (Group IV, n = 50) 3 minute before orotracheal intubation. The incidence of increasing MAP, SBP, DBP, and HR > 20% was compared between the two groups.
Results. The incidence of increasing MAP > 20% in IO group (29%) was significantly lower than IV group (56%) (p = 0,007), RR 0,52, CI 95% 0,32-0,85). The incidence of increasing SBP, DBP, and HR > 20% in IO group (27%, 29%, 9,8%) was significantly lower than IV group respectively (60%, 64%, 38%) (p = 0,007, p = 0,000, p = 0,001). Hemodynamic increase occur at 1 minute post orotracheal intubation and will return to basal at 3-10 minute post orotracheal intubation.
Conclusion. Adminitration oropharyngeal lidocaine 2% 5 cc instillation was better in decreasing hemodynamic changes post orotracheal intubation compared with intravenous lidocaine 2% 1,5 mg/bodyweight. |
first_indexed | 2024-03-13T22:39:34Z |
format | Thesis |
id | oai:generic.eprints.org:99574 |
institution | Universiti Gadjah Mada |
last_indexed | 2024-03-13T22:39:34Z |
publishDate | 2012 |
publisher | [Yogyakarta] : Universitas Gadjah Mada |
record_format | dspace |
spelling | oai:generic.eprints.org:995742016-03-04T08:45:44Z https://repository.ugm.ac.id/99574/ PERBANDINGAN PERUBAHAN HEMODINAMIK PASCAINTUBASI OROTRAKEA PADA PEMBERIAN LIDOKAIN 2% 5 cc INSTILASI OROFARINGEAL DENGAN LIDOKAIN 2% 1,5 mg/kgbb INTRAVENA , Asep Indah Wuddi Arief , dr. Pandit Sarosa, Sp.An-K ETD Background. Orotracheal intubation can cause increasing in hemodynamic responses which can increase morbidity and mortality. This study tested the hypothesis that oropharyngeal lidocaine instillation is better in decrease hemodynamic changes post orotracheal intubation compare with intravenous lidocaine. Methods. A prospective, randomized double blind controlled trial study was performed in 101 patient (ASA I-II) undergoing general anesthesia with orotracheal intubation. Patient were randomly allocated into one of two groups to receive oropharyngeal lidocaine 2% 5 cc (group IO, n = 51) and intravenous lidocaine 2% 1,5 mg/bodyweight (Group IV, n = 50) 3 minute before orotracheal intubation. The incidence of increasing MAP, SBP, DBP, and HR > 20% was compared between the two groups. Results. The incidence of increasing MAP > 20% in IO group (29%) was significantly lower than IV group (56%) (p = 0,007), RR 0,52, CI 95% 0,32-0,85). The incidence of increasing SBP, DBP, and HR > 20% in IO group (27%, 29%, 9,8%) was significantly lower than IV group respectively (60%, 64%, 38%) (p = 0,007, p = 0,000, p = 0,001). Hemodynamic increase occur at 1 minute post orotracheal intubation and will return to basal at 3-10 minute post orotracheal intubation. Conclusion. Adminitration oropharyngeal lidocaine 2% 5 cc instillation was better in decreasing hemodynamic changes post orotracheal intubation compared with intravenous lidocaine 2% 1,5 mg/bodyweight. [Yogyakarta] : Universitas Gadjah Mada 2012 Thesis NonPeerReviewed , Asep Indah Wuddi Arief and , dr. Pandit Sarosa, Sp.An-K (2012) PERBANDINGAN PERUBAHAN HEMODINAMIK PASCAINTUBASI OROTRAKEA PADA PEMBERIAN LIDOKAIN 2% 5 cc INSTILASI OROFARINGEAL DENGAN LIDOKAIN 2% 1,5 mg/kgbb INTRAVENA. UNSPECIFIED thesis, UNSPECIFIED. http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=56012 |
spellingShingle | ETD , Asep Indah Wuddi Arief , dr. Pandit Sarosa, Sp.An-K PERBANDINGAN PERUBAHAN HEMODINAMIK PASCAINTUBASI OROTRAKEA PADA PEMBERIAN LIDOKAIN 2% 5 cc INSTILASI OROFARINGEAL DENGAN LIDOKAIN 2% 1,5 mg/kgbb INTRAVENA |
title | PERBANDINGAN PERUBAHAN HEMODINAMIK
PASCAINTUBASI OROTRAKEA
PADA PEMBERIAN LIDOKAIN 2% 5 cc INSTILASI OROFARINGEAL DENGAN LIDOKAIN 2% 1,5 mg/kgbb INTRAVENA |
title_full | PERBANDINGAN PERUBAHAN HEMODINAMIK
PASCAINTUBASI OROTRAKEA
PADA PEMBERIAN LIDOKAIN 2% 5 cc INSTILASI OROFARINGEAL DENGAN LIDOKAIN 2% 1,5 mg/kgbb INTRAVENA |
title_fullStr | PERBANDINGAN PERUBAHAN HEMODINAMIK
PASCAINTUBASI OROTRAKEA
PADA PEMBERIAN LIDOKAIN 2% 5 cc INSTILASI OROFARINGEAL DENGAN LIDOKAIN 2% 1,5 mg/kgbb INTRAVENA |
title_full_unstemmed | PERBANDINGAN PERUBAHAN HEMODINAMIK
PASCAINTUBASI OROTRAKEA
PADA PEMBERIAN LIDOKAIN 2% 5 cc INSTILASI OROFARINGEAL DENGAN LIDOKAIN 2% 1,5 mg/kgbb INTRAVENA |
title_short | PERBANDINGAN PERUBAHAN HEMODINAMIK
PASCAINTUBASI OROTRAKEA
PADA PEMBERIAN LIDOKAIN 2% 5 cc INSTILASI OROFARINGEAL DENGAN LIDOKAIN 2% 1,5 mg/kgbb INTRAVENA |
title_sort | perbandingan perubahan hemodinamik pascaintubasi orotrakea pada pemberian lidokain 2 5 cc instilasi orofaringeal dengan lidokain 2 1 5 mg kgbb intravena |
topic | ETD |
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