| Summary: | Diabetes mellitus may lead to a macrovascular complication (eg.
aterosclerosis). Aterosclerosis causes thickenning of tunica intima and media of
common carotid artery due to hypertrophy. Measurement of tunica media of
carotid artery using ultrasonography (US) has been established for assessing
aterosclerosis and recommended by American Heart Association as a noninvasive
assessment for cardiovascular risk. We tried to evaluate and analyze the
correlation between type 2 diabetes mellitus and thickenning of tunica media and
intima of common carotid artery.
This was a crosss sectional analitic observational study. The study
population consisted of 31 patients with type 2 diabetes mellitus and 31 subjects
without diabetes mellitus who volunteered to be examined with high-resolution Bmode
US for common carotid artery thickness in Radiology Department of Dr.
Sardjito General Hospital between May and July 2011. Collected data were
proccessed and statistically analyzed using single t test. Correlation between risk
factors, other than diabetes mellitus, and thickenning of tunicas of common
carotid artery were analyzed using linear regresion analysis.
The results of this study showed that mean intimal medial thickness values
of the diabetic subjects (0,9342 ± 0,172 mm) were significantly higher than those
of the non-diabetic (0,6690 ± 0,083mm) subjects (p < 0.001). Multivariate linear
regression analysis showed that age, smoking and diabetes were the major risk
factors for intimal medial thickness. The Conclusion that diabetic subjects have
higher intimal medial thickness values than non-diabetic subjects. Diabetes are the
most important risk factors associated with increased intimal medial thickness in
this study.
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