Preliminary toxicity test and phytochemical screening of Sargassum Polycystum crude extracts from marine macroalgae / Norhayati Daud ... [et al.]
Sargassum polycystum is a species of brown algae (Phaeophyta). Some recent studies have found many uses of this algae, one of them is for medicine. In this study, crude hexane, dichloromethane and methanol extracts of Sargassum polycystum were tested for toxicity activity and screened for its princi...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Universiti Teknologi MARA, Pulau Pinang
2015
|
| Subjects: | |
| Online Access: | https://ir.uitm.edu.my/id/eprint/11997/1/AJ_NORHAYATI%20DAUD%20EAJ%2015.pdf |
| _version_ | 1825733996219203584 |
|---|---|
| author | Daud, Norhayati Mohd Noor, Nor Nafizah Alimon, Hasimah Abdul Rashid, Nursuhaidah |
| author_facet | Daud, Norhayati Mohd Noor, Nor Nafizah Alimon, Hasimah Abdul Rashid, Nursuhaidah |
| author_sort | Daud, Norhayati |
| collection | UITM |
| description | Sargassum polycystum is a species of brown algae (Phaeophyta). Some recent studies have found many uses of this algae, one of them is for medicine. In this study, crude hexane, dichloromethane and methanol extracts of Sargassum polycystum were tested for toxicity activity and screened for its principal chemical substances. The toxicity test was done using Brine Shrimp Lethality (BSL) test against Artemia salina Leach. The results of this study showed the LC50 value of methanol extract was 295.12 mgml-1, while both hexane and dichloromethane extracts were 275.42 mgml-1. The BSL test exhibited no significant toxicity against A.salina. Phytochemical screening shows S.
polycystum contained non polar and polar components. As the conclusion, S. polycystum contained secondary metabolites that are not toxic to A. salina and they are not a potential source for toxicity. |
| first_indexed | 2024-03-06T01:25:14Z |
| format | Article |
| id | oai:ir.uitm.edu.my:11997 |
| institution | Universiti Teknologi MARA |
| language | English |
| last_indexed | 2024-03-06T01:25:14Z |
| publishDate | 2015 |
| publisher | Universiti Teknologi MARA, Pulau Pinang |
| record_format | dspace |
| spelling | oai:ir.uitm.edu.my:119972016-07-27T00:36:49Z https://ir.uitm.edu.my/id/eprint/11997/ Preliminary toxicity test and phytochemical screening of Sargassum Polycystum crude extracts from marine macroalgae / Norhayati Daud ... [et al.] Daud, Norhayati Mohd Noor, Nor Nafizah Alimon, Hasimah Abdul Rashid, Nursuhaidah Toxicity testing Sea. Marine ecology. Ocean ecology Sargassum polycystum is a species of brown algae (Phaeophyta). Some recent studies have found many uses of this algae, one of them is for medicine. In this study, crude hexane, dichloromethane and methanol extracts of Sargassum polycystum were tested for toxicity activity and screened for its principal chemical substances. The toxicity test was done using Brine Shrimp Lethality (BSL) test against Artemia salina Leach. The results of this study showed the LC50 value of methanol extract was 295.12 mgml-1, while both hexane and dichloromethane extracts were 275.42 mgml-1. The BSL test exhibited no significant toxicity against A.salina. Phytochemical screening shows S. polycystum contained non polar and polar components. As the conclusion, S. polycystum contained secondary metabolites that are not toxic to A. salina and they are not a potential source for toxicity. Universiti Teknologi MARA, Pulau Pinang 2015 Article PeerReviewed text en https://ir.uitm.edu.my/id/eprint/11997/1/AJ_NORHAYATI%20DAUD%20EAJ%2015.pdf Preliminary toxicity test and phytochemical screening of Sargassum Polycystum crude extracts from marine macroalgae / Norhayati Daud ... [et al.]. (2015) Esteem Academic Journal <https://ir.uitm.edu.my/view/publication/Esteem_Academic_Journal/>, 11 (1). pp. 109-116. ISSN 1675-7939 |
| spellingShingle | Toxicity testing Sea. Marine ecology. Ocean ecology Daud, Norhayati Mohd Noor, Nor Nafizah Alimon, Hasimah Abdul Rashid, Nursuhaidah Preliminary toxicity test and phytochemical screening of Sargassum Polycystum crude extracts from marine macroalgae / Norhayati Daud ... [et al.] |
| title | Preliminary toxicity test and phytochemical screening of Sargassum Polycystum crude extracts from marine macroalgae / Norhayati Daud ... [et al.] |
| title_full | Preliminary toxicity test and phytochemical screening of Sargassum Polycystum crude extracts from marine macroalgae / Norhayati Daud ... [et al.] |
| title_fullStr | Preliminary toxicity test and phytochemical screening of Sargassum Polycystum crude extracts from marine macroalgae / Norhayati Daud ... [et al.] |
| title_full_unstemmed | Preliminary toxicity test and phytochemical screening of Sargassum Polycystum crude extracts from marine macroalgae / Norhayati Daud ... [et al.] |
| title_short | Preliminary toxicity test and phytochemical screening of Sargassum Polycystum crude extracts from marine macroalgae / Norhayati Daud ... [et al.] |
| title_sort | preliminary toxicity test and phytochemical screening of sargassum polycystum crude extracts from marine macroalgae norhayati daud et al |
| topic | Toxicity testing Sea. Marine ecology. Ocean ecology |
| url | https://ir.uitm.edu.my/id/eprint/11997/1/AJ_NORHAYATI%20DAUD%20EAJ%2015.pdf |
| work_keys_str_mv | AT daudnorhayati preliminarytoxicitytestandphytochemicalscreeningofsargassumpolycystumcrudeextractsfrommarinemacroalgaenorhayatidaudetal AT mohdnoornornafizah preliminarytoxicitytestandphytochemicalscreeningofsargassumpolycystumcrudeextractsfrommarinemacroalgaenorhayatidaudetal AT alimonhasimah preliminarytoxicitytestandphytochemicalscreeningofsargassumpolycystumcrudeextractsfrommarinemacroalgaenorhayatidaudetal AT abdulrashidnursuhaidah preliminarytoxicitytestandphytochemicalscreeningofsargassumpolycystumcrudeextractsfrommarinemacroalgaenorhayatidaudetal |