Design and development of high performance swa cell design for local DNA sequence alignment / Syed Abdul Mutalib Al Junid Syed Abdul Rahman

DNA sequence alignment is expected to help in revealing important information related to the human body, disease, genetic and other biological upon discovery of the sequence alignment. Moreover, there have been intensive efforts in improving the performance of the sequence alignment process via hard...

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Main Author: Syed Abdul Rahman, Syed Abdul Mutalib Al Junid
Format: Book Section
Language:English
Published: Institute of Graduate Studies, UiTM 2017
Subjects:
Online Access:https://ir.uitm.edu.my/id/eprint/19938/1/ABS_SYED%20ABDUL%20MUTALIB%20AL%20JUNID%20TDRA%20VOL%2012%20IGS%2017.pdf
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author Syed Abdul Rahman, Syed Abdul Mutalib Al Junid
author_facet Syed Abdul Rahman, Syed Abdul Mutalib Al Junid
author_sort Syed Abdul Rahman, Syed Abdul Mutalib Al Junid
collection UITM
description DNA sequence alignment is expected to help in revealing important information related to the human body, disease, genetic and other biological upon discovery of the sequence alignment. Moreover, there have been intensive efforts in improving the performance of the sequence alignment process via hardware-based acceleration using the Field Programmable Gate Array (FPGA). This implementation is becoming popular due to the flexibility of the acceleration design, the ability to reduce the execution cycle, parallel computational solutions, and the ability to increase the performance of alignment at the same time. The performance of the DNA sequence alignment system strongly depends on the algorithm, design architecture and accelerator performance. This study proposed three new DNA sequence alignment accelerator system cell design and architecture based on the Smith-Waterman Algorithm (SWA) named as the new Optimized SWA Linear Gap Penalty (OSL), Optimized SWA Affine Gap Penalty (OSA), and Optimized Recursive Variable Expansion SWA Linear Gap Penalty (ORSL).
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spelling oai:ir.uitm.edu.my:199382018-06-11T03:14:22Z https://ir.uitm.edu.my/id/eprint/19938/ Design and development of high performance swa cell design for local DNA sequence alignment / Syed Abdul Mutalib Al Junid Syed Abdul Rahman Syed Abdul Rahman, Syed Abdul Mutalib Al Junid Malaysia RB Pathology DNA sequence alignment is expected to help in revealing important information related to the human body, disease, genetic and other biological upon discovery of the sequence alignment. Moreover, there have been intensive efforts in improving the performance of the sequence alignment process via hardware-based acceleration using the Field Programmable Gate Array (FPGA). This implementation is becoming popular due to the flexibility of the acceleration design, the ability to reduce the execution cycle, parallel computational solutions, and the ability to increase the performance of alignment at the same time. The performance of the DNA sequence alignment system strongly depends on the algorithm, design architecture and accelerator performance. This study proposed three new DNA sequence alignment accelerator system cell design and architecture based on the Smith-Waterman Algorithm (SWA) named as the new Optimized SWA Linear Gap Penalty (OSL), Optimized SWA Affine Gap Penalty (OSA), and Optimized Recursive Variable Expansion SWA Linear Gap Penalty (ORSL). Institute of Graduate Studies, UiTM 2017 Book Section PeerReviewed text en https://ir.uitm.edu.my/id/eprint/19938/1/ABS_SYED%20ABDUL%20MUTALIB%20AL%20JUNID%20TDRA%20VOL%2012%20IGS%2017.pdf Design and development of high performance swa cell design for local DNA sequence alignment / Syed Abdul Mutalib Al Junid Syed Abdul Rahman. (2017) In: The Doctoral Research Abstracts. IGS Biannual Publication, 12 (12). Institute of Graduate Studies, UiTM, Shah Alam.
spellingShingle Malaysia
RB Pathology
Syed Abdul Rahman, Syed Abdul Mutalib Al Junid
Design and development of high performance swa cell design for local DNA sequence alignment / Syed Abdul Mutalib Al Junid Syed Abdul Rahman
title Design and development of high performance swa cell design for local DNA sequence alignment / Syed Abdul Mutalib Al Junid Syed Abdul Rahman
title_full Design and development of high performance swa cell design for local DNA sequence alignment / Syed Abdul Mutalib Al Junid Syed Abdul Rahman
title_fullStr Design and development of high performance swa cell design for local DNA sequence alignment / Syed Abdul Mutalib Al Junid Syed Abdul Rahman
title_full_unstemmed Design and development of high performance swa cell design for local DNA sequence alignment / Syed Abdul Mutalib Al Junid Syed Abdul Rahman
title_short Design and development of high performance swa cell design for local DNA sequence alignment / Syed Abdul Mutalib Al Junid Syed Abdul Rahman
title_sort design and development of high performance swa cell design for local dna sequence alignment syed abdul mutalib al junid syed abdul rahman
topic Malaysia
RB Pathology
url https://ir.uitm.edu.my/id/eprint/19938/1/ABS_SYED%20ABDUL%20MUTALIB%20AL%20JUNID%20TDRA%20VOL%2012%20IGS%2017.pdf
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