Prevalence of coronary artery disease in young sudden death cases and correlation with post-mortem computed tomography calcium score / Omar E. … [et al.]
Data on prevalence of coronary atherosclerosis and coronary artery disease (CAD) in young sudden death autopsy cases in Malaysia are still scarce. Calcium scoring (CS) on Computed Tomography (CT) was suggested to be predictive for CAD; however the reports have been conflicting. Objectives: to invest...
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| Format: | Article |
| Language: | English |
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Universiti Teknologi MARA Cawangan Selangor
2018
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| Online Access: | https://ir.uitm.edu.my/id/eprint/30104/1/AJ_OMAR%20E%20JCHS%20B%2018.pdf |
| _version_ | 1825737123222781952 |
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| author | Omar, Effat R., Faizuddin Chaincel Singh, Mansharan Kaur Rahimi, Razuin Mahmood, Mohd Shah Abdullah, Nurliza Abdul Manaf, Zaleha Nawawi, Hapizah |
| author_facet | Omar, Effat R., Faizuddin Chaincel Singh, Mansharan Kaur Rahimi, Razuin Mahmood, Mohd Shah Abdullah, Nurliza Abdul Manaf, Zaleha Nawawi, Hapizah |
| author_sort | Omar, Effat |
| collection | UITM |
| description | Data on prevalence of coronary atherosclerosis and coronary artery disease (CAD) in young sudden death autopsy cases in Malaysia are still scarce. Calcium scoring (CS) on Computed Tomography (CT) was suggested to be predictive for CAD; however the reports have been conflicting. Objectives: to investigate (i) the prevalence of young CAD in sudden death cases in a Malaysian population; (ii) the association between CT CS and CAD in such cases and correlation with age. Methods: Sudden death cases received at the National Institute of Forensic Medicine, Kuala Lumpur between September 2012 and December 2013 were recruited. The cases were divided into young [=40] and old [>40 years old] age groups. Presence of CAD was recorded during autopsy. Results: A total of 155 cases was included; 64.5% of the subjects were below 40 years old. CAD was the cause of death of 34 [21.9%] cases; of these, young individuals comprise 47.1% of cases [n=16; 10.3% of total cases, 16% of young sudden death cases]. Both young and old subjects with CAD had lower CS compared to those without CAD [p<0.000; p=0.003 respectively]. Multivariable regression analysis showed CS to be significantly correlated with CAD in both young and old subjects. In contrast, other factors such as gender, ethnicity, body-mass index and waist-hip ratio did not show any correlation with CAD in both groups. Conclusion: The revalence of CAD in young sudden death cases is relatively high. CS is useful in discriminating CAD in both young and old SD subjects. |
| first_indexed | 2024-03-06T02:13:17Z |
| format | Article |
| id | oai:ir.uitm.edu.my:30104 |
| institution | Universiti Teknologi MARA |
| language | English |
| last_indexed | 2024-03-06T02:13:17Z |
| publishDate | 2018 |
| publisher | Universiti Teknologi MARA Cawangan Selangor |
| record_format | dspace |
| spelling | oai:ir.uitm.edu.my:301042020-04-22T05:34:09Z https://ir.uitm.edu.my/id/eprint/30104/ Prevalence of coronary artery disease in young sudden death cases and correlation with post-mortem computed tomography calcium score / Omar E. … [et al.] jchs Omar, Effat R., Faizuddin Chaincel Singh, Mansharan Kaur Rahimi, Razuin Mahmood, Mohd Shah Abdullah, Nurliza Abdul Manaf, Zaleha Nawawi, Hapizah Specialties of internal medicine Diseases of the circulatory (Cardiovascular) system Data on prevalence of coronary atherosclerosis and coronary artery disease (CAD) in young sudden death autopsy cases in Malaysia are still scarce. Calcium scoring (CS) on Computed Tomography (CT) was suggested to be predictive for CAD; however the reports have been conflicting. Objectives: to investigate (i) the prevalence of young CAD in sudden death cases in a Malaysian population; (ii) the association between CT CS and CAD in such cases and correlation with age. Methods: Sudden death cases received at the National Institute of Forensic Medicine, Kuala Lumpur between September 2012 and December 2013 were recruited. The cases were divided into young [=40] and old [>40 years old] age groups. Presence of CAD was recorded during autopsy. Results: A total of 155 cases was included; 64.5% of the subjects were below 40 years old. CAD was the cause of death of 34 [21.9%] cases; of these, young individuals comprise 47.1% of cases [n=16; 10.3% of total cases, 16% of young sudden death cases]. Both young and old subjects with CAD had lower CS compared to those without CAD [p<0.000; p=0.003 respectively]. Multivariable regression analysis showed CS to be significantly correlated with CAD in both young and old subjects. In contrast, other factors such as gender, ethnicity, body-mass index and waist-hip ratio did not show any correlation with CAD in both groups. Conclusion: The revalence of CAD in young sudden death cases is relatively high. CS is useful in discriminating CAD in both young and old SD subjects. Universiti Teknologi MARA Cawangan Selangor 2018-06 Article PeerReviewed text en https://ir.uitm.edu.my/id/eprint/30104/1/AJ_OMAR%20E%20JCHS%20B%2018.pdf Prevalence of coronary artery disease in young sudden death cases and correlation with post-mortem computed tomography calcium score / Omar E. … [et al.]. (2018) Journal of Clinical and Health Sciences <https://ir.uitm.edu.my/view/publication/Journal_of_Clinical_and_Health_Sciences/>, 3 (1). pp. 1-6. ISSN 0127-984X https://jchs-medicine.uitm.edu.my/index.php |
| spellingShingle | Specialties of internal medicine Diseases of the circulatory (Cardiovascular) system Omar, Effat R., Faizuddin Chaincel Singh, Mansharan Kaur Rahimi, Razuin Mahmood, Mohd Shah Abdullah, Nurliza Abdul Manaf, Zaleha Nawawi, Hapizah Prevalence of coronary artery disease in young sudden death cases and correlation with post-mortem computed tomography calcium score / Omar E. … [et al.] |
| title | Prevalence of coronary artery disease in young sudden death cases and correlation with post-mortem computed tomography calcium score / Omar E. … [et al.] |
| title_full | Prevalence of coronary artery disease in young sudden death cases and correlation with post-mortem computed tomography calcium score / Omar E. … [et al.] |
| title_fullStr | Prevalence of coronary artery disease in young sudden death cases and correlation with post-mortem computed tomography calcium score / Omar E. … [et al.] |
| title_full_unstemmed | Prevalence of coronary artery disease in young sudden death cases and correlation with post-mortem computed tomography calcium score / Omar E. … [et al.] |
| title_short | Prevalence of coronary artery disease in young sudden death cases and correlation with post-mortem computed tomography calcium score / Omar E. … [et al.] |
| title_sort | prevalence of coronary artery disease in young sudden death cases and correlation with post mortem computed tomography calcium score omar e et al |
| topic | Specialties of internal medicine Diseases of the circulatory (Cardiovascular) system |
| url | https://ir.uitm.edu.my/id/eprint/30104/1/AJ_OMAR%20E%20JCHS%20B%2018.pdf |
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