Antibacterial and toxicity properties of biosynthesized silver nanoparticles by lawsonia inermis extract / Nur Syazana Satteri
Biosynthesis of silver nanoparticles using plant extracts are currently being explored as an alternative approach in pharmaceutical and medical field. The aims of this study was synthesized and characterized silver nanoparticles (AgNPs) by using UV-Vis spectrophotometer, identified their antibacteri...
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| Format: | Thesis |
| Language: | English |
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2020
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| Online Access: | https://ir.uitm.edu.my/id/eprint/36474/1/36474.pdf |
| _version_ | 1825738310227591168 |
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| author | Satteri, Nur Syazana |
| author_facet | Satteri, Nur Syazana |
| author_sort | Satteri, Nur Syazana |
| collection | UITM |
| description | Biosynthesis of silver nanoparticles using plant extracts are currently being explored as an alternative approach in pharmaceutical and medical field. The aims of this study was synthesized and characterized silver nanoparticles (AgNPs) by using UV-Vis spectrophotometer, identified their antibacterial and toxicity activity. The biosynthesized of AgNPs were varies in the reaction time (1, 2, 3, 6 and 7) days, was characterized by UV-Vis spectrophotometer (200-600 nm). The determination of antibacterial and toxicity assays of Lawsonia inermis was done by Kirby–Bauer disc diffusion method (Gram-positive and Gram-negative bacterial strains) and Brine Shrimp Lethality Assay respectively. From the result, L. inermis leaf extract was reduced the silver ions and indicates the formation of silver nanoparticles by changing colour from dark brown to colloidal grey. The highest peak of biosynthesized silver nanoparticles from L. inermis extract in range from 420 nm to 471 nm. Zone inhibition for Gram-positive and Gram-negative bacterial strains at 1000 μg/ml was 12.00 mm and 12.33 mm respectively. The LC50 of biosynthesized AgNPs at 1000 μg/ml was observed 7367.233 which indicate non-toxic towards the brine shrimp. To conclude, AgNPs synthesized from L. inermis leaves extract would be very efficient to be an alternative for antibacterial. |
| first_indexed | 2024-03-06T02:31:36Z |
| format | Thesis |
| id | oai:ir.uitm.edu.my:36474 |
| institution | Universiti Teknologi MARA |
| language | English |
| last_indexed | 2024-03-06T02:31:36Z |
| publishDate | 2020 |
| record_format | dspace |
| spelling | oai:ir.uitm.edu.my:364742020-11-12T02:53:19Z https://ir.uitm.edu.my/id/eprint/36474/ Antibacterial and toxicity properties of biosynthesized silver nanoparticles by lawsonia inermis extract / Nur Syazana Satteri Satteri, Nur Syazana Extraction (Chemistry) Toxicity testing Bacteria Biosynthesis of silver nanoparticles using plant extracts are currently being explored as an alternative approach in pharmaceutical and medical field. The aims of this study was synthesized and characterized silver nanoparticles (AgNPs) by using UV-Vis spectrophotometer, identified their antibacterial and toxicity activity. The biosynthesized of AgNPs were varies in the reaction time (1, 2, 3, 6 and 7) days, was characterized by UV-Vis spectrophotometer (200-600 nm). The determination of antibacterial and toxicity assays of Lawsonia inermis was done by Kirby–Bauer disc diffusion method (Gram-positive and Gram-negative bacterial strains) and Brine Shrimp Lethality Assay respectively. From the result, L. inermis leaf extract was reduced the silver ions and indicates the formation of silver nanoparticles by changing colour from dark brown to colloidal grey. The highest peak of biosynthesized silver nanoparticles from L. inermis extract in range from 420 nm to 471 nm. Zone inhibition for Gram-positive and Gram-negative bacterial strains at 1000 μg/ml was 12.00 mm and 12.33 mm respectively. The LC50 of biosynthesized AgNPs at 1000 μg/ml was observed 7367.233 which indicate non-toxic towards the brine shrimp. To conclude, AgNPs synthesized from L. inermis leaves extract would be very efficient to be an alternative for antibacterial. 2020-11-09 Thesis NonPeerReviewed text en https://ir.uitm.edu.my/id/eprint/36474/1/36474.pdf Antibacterial and toxicity properties of biosynthesized silver nanoparticles by lawsonia inermis extract / Nur Syazana Satteri. (2020) Degree thesis, thesis, Universiti Teknologi Mara Perlis. |
| spellingShingle | Extraction (Chemistry) Toxicity testing Bacteria Satteri, Nur Syazana Antibacterial and toxicity properties of biosynthesized silver nanoparticles by lawsonia inermis extract / Nur Syazana Satteri |
| title | Antibacterial and toxicity properties of biosynthesized silver nanoparticles by lawsonia inermis extract / Nur Syazana Satteri |
| title_full | Antibacterial and toxicity properties of biosynthesized silver nanoparticles by lawsonia inermis extract / Nur Syazana Satteri |
| title_fullStr | Antibacterial and toxicity properties of biosynthesized silver nanoparticles by lawsonia inermis extract / Nur Syazana Satteri |
| title_full_unstemmed | Antibacterial and toxicity properties of biosynthesized silver nanoparticles by lawsonia inermis extract / Nur Syazana Satteri |
| title_short | Antibacterial and toxicity properties of biosynthesized silver nanoparticles by lawsonia inermis extract / Nur Syazana Satteri |
| title_sort | antibacterial and toxicity properties of biosynthesized silver nanoparticles by lawsonia inermis extract nur syazana satteri |
| topic | Extraction (Chemistry) Toxicity testing Bacteria |
| url | https://ir.uitm.edu.my/id/eprint/36474/1/36474.pdf |
| work_keys_str_mv | AT satterinursyazana antibacterialandtoxicitypropertiesofbiosynthesizedsilvernanoparticlesbylawsoniainermisextractnursyazanasatteri |