Structural lipid nanoparticles self-assembled from electrospun core-shell polymeric nanocomposites
Electrospun polymeric core–shell nanocomposites are exploited as templates to manipulate molecular self-assembly for preparing structural lipid nanoparticles, during which the confinement effect of fibers together with their core–shell structure, the aqueous environment and the secondary interaction...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Royal Society of Chemistry
2015
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| Subjects: | |
| Online Access: | https://repository.londonmet.ac.uk/1034/1/RSC%20Adv%20v5%20p9462%202015%20%5BKW057%5D.pdf |
| _version_ | 1804071619636756480 |
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| author | Yu, Deng-Guang White, Kenneth Chatterton, Nicholas Li, Ying Li, Lingling Wang, Xia |
| author_facet | Yu, Deng-Guang White, Kenneth Chatterton, Nicholas Li, Ying Li, Lingling Wang, Xia |
| author_sort | Yu, Deng-Guang |
| collection | LMU |
| description | Electrospun polymeric core–shell nanocomposites are exploited as templates to manipulate molecular self-assembly for preparing structural lipid nanoparticles, during which the confinement effect of fibers together with their core–shell structure, the aqueous environment and the secondary interactions, all contributed synergistically to facilitate molecular self-aggregation to produce lipid nanoparticles with a drug entrapment efficiency of 95.9% with a sustained drug release profile. |
| first_indexed | 2024-07-09T03:46:08Z |
| format | Article |
| id | oai:repository.londonmet.ac.uk:1034 |
| institution | London Metropolitan University |
| language | English |
| last_indexed | 2024-07-09T03:46:08Z |
| publishDate | 2015 |
| publisher | Royal Society of Chemistry |
| record_format | eprints |
| spelling | oai:repository.londonmet.ac.uk:10342020-06-04T11:56:48Z http://repository.londonmet.ac.uk/1034/ Structural lipid nanoparticles self-assembled from electrospun core-shell polymeric nanocomposites Yu, Deng-Guang White, Kenneth Chatterton, Nicholas Li, Ying Li, Lingling Wang, Xia 540 Chemistry & allied sciences Electrospun polymeric core–shell nanocomposites are exploited as templates to manipulate molecular self-assembly for preparing structural lipid nanoparticles, during which the confinement effect of fibers together with their core–shell structure, the aqueous environment and the secondary interactions, all contributed synergistically to facilitate molecular self-aggregation to produce lipid nanoparticles with a drug entrapment efficiency of 95.9% with a sustained drug release profile. Royal Society of Chemistry 2015 Article PeerReviewed text en https://repository.londonmet.ac.uk/1034/1/RSC%20Adv%20v5%20p9462%202015%20%5BKW057%5D.pdf Yu, Deng-Guang, White, Kenneth, Chatterton, Nicholas, Li, Ying, Li, Lingling and Wang, Xia (2015) Structural lipid nanoparticles self-assembled from electrospun core-shell polymeric nanocomposites. RSC Advances, 5. pp. 9462-9466. ISSN 2046-2069 http://www.rsc.org/advances 10.1039/c4ra14001j |
| spellingShingle | 540 Chemistry & allied sciences Yu, Deng-Guang White, Kenneth Chatterton, Nicholas Li, Ying Li, Lingling Wang, Xia Structural lipid nanoparticles self-assembled from electrospun core-shell polymeric nanocomposites |
| title | Structural lipid nanoparticles self-assembled from electrospun core-shell polymeric nanocomposites |
| title_full | Structural lipid nanoparticles self-assembled from electrospun core-shell polymeric nanocomposites |
| title_fullStr | Structural lipid nanoparticles self-assembled from electrospun core-shell polymeric nanocomposites |
| title_full_unstemmed | Structural lipid nanoparticles self-assembled from electrospun core-shell polymeric nanocomposites |
| title_short | Structural lipid nanoparticles self-assembled from electrospun core-shell polymeric nanocomposites |
| title_sort | structural lipid nanoparticles self assembled from electrospun core shell polymeric nanocomposites |
| topic | 540 Chemistry & allied sciences |
| url | https://repository.londonmet.ac.uk/1034/1/RSC%20Adv%20v5%20p9462%202015%20%5BKW057%5D.pdf |
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