NNT is a key regulator of adrenal redox homeostasis and steroidogenesis in male mice

NNT is a key regulator of adrenal redox homeostasis and steroidogenesis in male mice

Nicotinamide nucleotide transhydrogenase, NNT, is a ubiquitous protein of the inner mitochondrial membrane with a key role in mitochondrial redox balance. NNT produces high concentrations of NADPH for detoxification of reactive oxygen species by glutathione and thioredoxin pathways. In humans, NNT d...

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Bibliographic Details
Main Authors: Meimaridou, Eirini, Goldsworthy, Michelle, Chortis, Vasileios, Fragouli, Elpida, Foster, Paul A., Arlt, Wiebke, Cox, Roger D., Metherell, Louise A.
Format: Article
Language:English
Published: BioScientifica 2018
Subjects:
570 Life sciences; biology
Online Access:https://repository.londonmet.ac.uk/1409/1/JOE-16-0638-accepted%20pdf.full.pdf

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