Randomised open-label trial of docosahexaenoic acid-enriched fish oil and fish meal on cognitive and behavioural functioning in Omani children
Objective: Examine the effect of docosahexaenoic acid (DHA) enriched fish oil supplement and fish meal on cognitive and behavioural functioning manifested as attention-deficit/hyperactivity disorder in primary school students (9-10 years old) in Muscat, Oman. Methods: Randomised open-label trial...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2018
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| Online Access: | https://repository.londonmet.ac.uk/1434/1/Nutrition-2018-04-008.pdf |
| _version_ | 1804071675239596032 |
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| author | Al-Ghannami, Samia S. Al-Adawi, Samir Ghebremeskel, Kebreab Hussein, Izzeldin S. Min, Yoeju Jeyaseelan, Lakshmanan Al-Shammakhi, Saleh M. Mabry, Ruth M. Al-Oufi, Hamed S. |
| author_facet | Al-Ghannami, Samia S. Al-Adawi, Samir Ghebremeskel, Kebreab Hussein, Izzeldin S. Min, Yoeju Jeyaseelan, Lakshmanan Al-Shammakhi, Saleh M. Mabry, Ruth M. Al-Oufi, Hamed S. |
| author_sort | Al-Ghannami, Samia S. |
| collection | LMU |
| description | Objective: Examine the effect of docosahexaenoic acid (DHA) enriched fish oil supplement and fish meal on cognitive and behavioural functioning manifested as attention-deficit/hyperactivity disorder in primary school students (9-10 years old) in Muscat, Oman.
Methods: Randomised open-label trial involving two types of intervention: fish oil supplement or one serving (100 gram) of fish per weekday for 12 weeks. Red cell total lipid docosahexaenoic acid levels were assessed. Verbal Fluency Test, Buschke Selective Reminding Test, and Trail Making Test were used to measure cognitive functioning. Behavioural functioning was assessed using a standardised Arabic version of the National Initiative for Children’s Health Quality Vanderbilt Assessment Scales. All measurements were carried out before and after intervention.
Results: DHA levels increased by 72% and 64% in fish oil (Mean: 3.6% to 6.2%) and fish meal (Mean: 3.4% to 5.6%) group, respectively (p=0.000). The Trail Making Test was the only cognitive test that demonstrated marked differences between groups: median inter-quartile range difference between pre and post intervention in the Trail Making Part B score was 61.5 (SE: 19.3, 103.2) in the fish oil vs. Fish meal group, 24.5 (SE: -15.2, 74.7, p=0.005). The Vanderbilt Assessment Scales also showed significant differences between groups (p<0.001).
Conclusion: This study contributes to available evidence on the cognitive and behavioural benefits of DHA in healthy school children. Consideration should be made to expand the food fortification programme as part of broader policy to improve child health. |
| first_indexed | 2024-07-09T03:47:01Z |
| format | Article |
| id | oai:repository.londonmet.ac.uk:1434 |
| institution | London Metropolitan University |
| language | English |
| last_indexed | 2024-07-09T03:47:01Z |
| publishDate | 2018 |
| publisher | Elsevier |
| record_format | eprints |
| spelling | oai:repository.londonmet.ac.uk:14342020-04-07T13:45:47Z http://repository.londonmet.ac.uk/1434/ Randomised open-label trial of docosahexaenoic acid-enriched fish oil and fish meal on cognitive and behavioural functioning in Omani children Al-Ghannami, Samia S. Al-Adawi, Samir Ghebremeskel, Kebreab Hussein, Izzeldin S. Min, Yoeju Jeyaseelan, Lakshmanan Al-Shammakhi, Saleh M. Mabry, Ruth M. Al-Oufi, Hamed S. 150 Psychology 570 Life sciences; biology Objective: Examine the effect of docosahexaenoic acid (DHA) enriched fish oil supplement and fish meal on cognitive and behavioural functioning manifested as attention-deficit/hyperactivity disorder in primary school students (9-10 years old) in Muscat, Oman. Methods: Randomised open-label trial involving two types of intervention: fish oil supplement or one serving (100 gram) of fish per weekday for 12 weeks. Red cell total lipid docosahexaenoic acid levels were assessed. Verbal Fluency Test, Buschke Selective Reminding Test, and Trail Making Test were used to measure cognitive functioning. Behavioural functioning was assessed using a standardised Arabic version of the National Initiative for Children’s Health Quality Vanderbilt Assessment Scales. All measurements were carried out before and after intervention. Results: DHA levels increased by 72% and 64% in fish oil (Mean: 3.6% to 6.2%) and fish meal (Mean: 3.4% to 5.6%) group, respectively (p=0.000). The Trail Making Test was the only cognitive test that demonstrated marked differences between groups: median inter-quartile range difference between pre and post intervention in the Trail Making Part B score was 61.5 (SE: 19.3, 103.2) in the fish oil vs. Fish meal group, 24.5 (SE: -15.2, 74.7, p=0.005). The Vanderbilt Assessment Scales also showed significant differences between groups (p<0.001). Conclusion: This study contributes to available evidence on the cognitive and behavioural benefits of DHA in healthy school children. Consideration should be made to expand the food fortification programme as part of broader policy to improve child health. Elsevier 2018-05-17 Article PeerReviewed text en https://repository.londonmet.ac.uk/1434/1/Nutrition-2018-04-008.pdf Al-Ghannami, Samia S., Al-Adawi, Samir, Ghebremeskel, Kebreab, Hussein, Izzeldin S., Min, Yoeju, Jeyaseelan, Lakshmanan, Al-Shammakhi, Saleh M., Mabry, Ruth M. and Al-Oufi, Hamed S. (2018) Randomised open-label trial of docosahexaenoic acid-enriched fish oil and fish meal on cognitive and behavioural functioning in Omani children. Nutrition. ISSN 0899-9007 https://ees.elsevier.com/nut/default.asp?acw=&utt= NUT 10200 |
| spellingShingle | 150 Psychology 570 Life sciences; biology Al-Ghannami, Samia S. Al-Adawi, Samir Ghebremeskel, Kebreab Hussein, Izzeldin S. Min, Yoeju Jeyaseelan, Lakshmanan Al-Shammakhi, Saleh M. Mabry, Ruth M. Al-Oufi, Hamed S. Randomised open-label trial of docosahexaenoic acid-enriched fish oil and fish meal on cognitive and behavioural functioning in Omani children |
| title | Randomised open-label trial of docosahexaenoic acid-enriched fish oil and fish meal on cognitive and behavioural functioning in Omani children |
| title_full | Randomised open-label trial of docosahexaenoic acid-enriched fish oil and fish meal on cognitive and behavioural functioning in Omani children |
| title_fullStr | Randomised open-label trial of docosahexaenoic acid-enriched fish oil and fish meal on cognitive and behavioural functioning in Omani children |
| title_full_unstemmed | Randomised open-label trial of docosahexaenoic acid-enriched fish oil and fish meal on cognitive and behavioural functioning in Omani children |
| title_short | Randomised open-label trial of docosahexaenoic acid-enriched fish oil and fish meal on cognitive and behavioural functioning in Omani children |
| title_sort | randomised open label trial of docosahexaenoic acid enriched fish oil and fish meal on cognitive and behavioural functioning in omani children |
| topic | 150 Psychology 570 Life sciences; biology |
| url | https://repository.londonmet.ac.uk/1434/1/Nutrition-2018-04-008.pdf |
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