Use of LC-MS analysis to elucidate by-products of niacinamide transformation following in vitro skin permeation studies
Pyridine-3-carboxamide, also known as niacinamide (NIA), is used in many pharmaceutical and personal care formulations for the improvement of skin barrier function, management of acne and amelioration of the symptoms of atopic dermatitis [1-3]. The widespread use of NIA (Table I) in skin care highli...
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| Format: | Article |
| Language: | English |
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Wiley
2018
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| Online Access: | https://repository.londonmet.ac.uk/2869/1/ics.12486.pdf |
| _version_ | 1825625031879688192 |
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| author | Sil dos Santos, Bruno Moore, David J. |
| author_facet | Sil dos Santos, Bruno Moore, David J. |
| author_sort | Sil dos Santos, Bruno |
| collection | LMU |
| description | Pyridine-3-carboxamide, also known as niacinamide (NIA), is used in many pharmaceutical and personal care formulations for the improvement of skin barrier function, management of acne and amelioration of the symptoms of atopic dermatitis [1-3]. The widespread use of NIA (Table I) in skin care highlights the importance of understanding the percutaneous penetration and skin distribution of this molecule [4]. Previously, we have conducted several studies that have evaluated a wide variety of NIA formulations [4, 5]. |
| first_indexed | 2024-07-09T03:52:00Z |
| format | Article |
| id | oai:repository.londonmet.ac.uk:2869 |
| institution | London Metropolitan University |
| language | English |
| last_indexed | 2024-07-09T03:52:00Z |
| publishDate | 2018 |
| publisher | Wiley |
| record_format | eprints |
| spelling | oai:repository.londonmet.ac.uk:28692020-04-06T10:57:11Z https://repository.londonmet.ac.uk/2869/ Use of LC-MS analysis to elucidate by-products of niacinamide transformation following in vitro skin permeation studies Sil dos Santos, Bruno Moore, David J. 610 Medicine & health Pyridine-3-carboxamide, also known as niacinamide (NIA), is used in many pharmaceutical and personal care formulations for the improvement of skin barrier function, management of acne and amelioration of the symptoms of atopic dermatitis [1-3]. The widespread use of NIA (Table I) in skin care highlights the importance of understanding the percutaneous penetration and skin distribution of this molecule [4]. Previously, we have conducted several studies that have evaluated a wide variety of NIA formulations [4, 5]. Wiley 2018-08-04 Article PeerReviewed text en https://repository.londonmet.ac.uk/2869/1/ics.12486.pdf Sil dos Santos, Bruno and Moore, David J. (2018) Use of LC-MS analysis to elucidate by-products of niacinamide transformation following in vitro skin permeation studies. International journal of cosmetic science, 40 (5). pp. 525-529. ISSN 1468-2494 10.1111/ics.12486 10.1111/ics.12486 |
| spellingShingle | 610 Medicine & health Sil dos Santos, Bruno Moore, David J. Use of LC-MS analysis to elucidate by-products of niacinamide transformation following in vitro skin permeation studies |
| title | Use of LC-MS analysis to elucidate by-products of niacinamide transformation following in vitro skin permeation studies |
| title_full | Use of LC-MS analysis to elucidate by-products of niacinamide transformation following in vitro skin permeation studies |
| title_fullStr | Use of LC-MS analysis to elucidate by-products of niacinamide transformation following in vitro skin permeation studies |
| title_full_unstemmed | Use of LC-MS analysis to elucidate by-products of niacinamide transformation following in vitro skin permeation studies |
| title_short | Use of LC-MS analysis to elucidate by-products of niacinamide transformation following in vitro skin permeation studies |
| title_sort | use of lc ms analysis to elucidate by products of niacinamide transformation following in vitro skin permeation studies |
| topic | 610 Medicine & health |
| url | https://repository.londonmet.ac.uk/2869/1/ics.12486.pdf |
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