The synthesis and pharmacology of some novel excitatory amino acid analogues
Certain amino acids, notably L-glutamate and L-aspartate, are believed to fulfil a role as excitatory neurotransmitters in the mammalian Central Nervous System (CNS). Investigation has revealed the presence of three, and possibly a fourth, type of receptor for such neurotransmitters. These receptors...
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| Format: | Thesis |
| Language: | English |
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1986
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| Online Access: | https://repository.londonmet.ac.uk/3278/1/372742.pdf |
| _version_ | 1804072079463546880 |
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| author | Badman, G. T. |
| author_facet | Badman, G. T. |
| author_sort | Badman, G. T. |
| collection | LMU |
| description | Certain amino acids, notably L-glutamate and L-aspartate, are believed to fulfil a role as excitatory neurotransmitters in the mammalian Central Nervous System (CNS). Investigation has revealed the presence of three, and possibly a fourth, type of receptor for such neurotransmitters. These receptors have been named after the most potent and selective agonist of each; thus they are usually referred to as N-methyl-D-aspartate (A1), quisqualate (A2), kainate (A3) and 2-amino, 4-phosphono butyric acid (A4); the designations in brackets being that of the nomenclature of Fagg and Foster. |
| first_indexed | 2024-07-09T03:53:27Z |
| format | Thesis |
| id | oai:repository.londonmet.ac.uk:3278 |
| institution | London Metropolitan University |
| language | English |
| last_indexed | 2024-07-09T03:53:27Z |
| publishDate | 1986 |
| record_format | eprints |
| spelling | oai:repository.londonmet.ac.uk:32782018-09-20T14:17:14Z http://repository.londonmet.ac.uk/3278/ The synthesis and pharmacology of some novel excitatory amino acid analogues Badman, G. T. 540 Chemistry & allied sciences 610 Medicine & health Certain amino acids, notably L-glutamate and L-aspartate, are believed to fulfil a role as excitatory neurotransmitters in the mammalian Central Nervous System (CNS). Investigation has revealed the presence of three, and possibly a fourth, type of receptor for such neurotransmitters. These receptors have been named after the most potent and selective agonist of each; thus they are usually referred to as N-methyl-D-aspartate (A1), quisqualate (A2), kainate (A3) and 2-amino, 4-phosphono butyric acid (A4); the designations in brackets being that of the nomenclature of Fagg and Foster. 1986-09 Thesis NonPeerReviewed text en https://repository.londonmet.ac.uk/3278/1/372742.pdf Badman, G. T. (1986) The synthesis and pharmacology of some novel excitatory amino acid analogues. Doctoral thesis, City of London Polytechnic. |
| spellingShingle | 540 Chemistry & allied sciences 610 Medicine & health Badman, G. T. The synthesis and pharmacology of some novel excitatory amino acid analogues |
| title | The synthesis and pharmacology of some novel excitatory amino acid analogues |
| title_full | The synthesis and pharmacology of some novel excitatory amino acid analogues |
| title_fullStr | The synthesis and pharmacology of some novel excitatory amino acid analogues |
| title_full_unstemmed | The synthesis and pharmacology of some novel excitatory amino acid analogues |
| title_short | The synthesis and pharmacology of some novel excitatory amino acid analogues |
| title_sort | synthesis and pharmacology of some novel excitatory amino acid analogues |
| topic | 540 Chemistry & allied sciences 610 Medicine & health |
| url | https://repository.londonmet.ac.uk/3278/1/372742.pdf |
| work_keys_str_mv | AT badmangt thesynthesisandpharmacologyofsomenovelexcitatoryaminoacidanalogues AT badmangt synthesisandpharmacologyofsomenovelexcitatoryaminoacidanalogues |